Abstract: A biomaterial, particularly for tissue regeneration, includes an open, porous bioresorbable first material portion and a second material portion that is stiffer than the first material portion, wherein the volume fraction of the stiffer material is less than 30% of the total volume of the biomaterial, and the structural stiffness of the second material portion is at least 10 times greater than that of the first material portion.

Abstract: A biomaterial, particularly for tissue regeneration, includes an open, porous bioresorbable first material portion and a second material portion that is stiffer than the first material portion, wherein the volume fraction of the stiffer material is less than 30% of the total volume of the biomaterial, and the structural stiffness of the second material portion is at least 10 times greater than that of the first material portion.

Abstract: In order to achieve a reproducible treatment for materials of biological origin such as membranes, skins, vessels, heart valves, tendons and ligaments and, in particular, collagen materials, hydrophobic accompanying substances are, first of all, chemically removed without the accompanying substances being chemically altered. Non-hydrophobic accompanying substances are subsequently removed. The materials treated in this manner are used to form membranes, heart valves or vessels or are further processed to form solutions, fibers, fiber weaves, fibrous tissues or sponges and are optionally populated with cells and/or used for carrying out controlled tissue regeneration.

Abstract: A method for producing porous structures in which a liquid or pasty mixture of substances is brought at least partially to solidification and subsequently freeze-dried.

Abstract: To improve the thermal transmission during freezing processes it is proposed that the goods to be cooled and a pre-cooled body of high thermal capacity be pressed against each other. Improved thermal transmission is also attained with a device comprising a holding device which during the cooling process holds the goods to be cooled essentially in a non-deformable way, allowing direct contact between the coolant and the goods to be cooled. Preferably, vertically aligned channels are arranged between the holding device and the goods to be cooled, with coolant flowing in said channels.