Patents by Inventor Ingo Kai Mellinghoff

Ingo Kai Mellinghoff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PLATELET-DERIVED GROWTH FACTOR RECEPTOR MUTATIONS AND COMPOSITIONS AND METHODS RELATING THERETO
    Publication number: 20210008073
    Abstract: In certain embodiments the present invention involves methods of killing tumor cells that comprise an oncogenic PDGFR mutation, and methods of treating subjects having tumors that comprise such tumor cells. In some embodiments such methods involve using PI3K inhibitors, or a combination of a PI3K inhibitor and an mTOR inhibitor, or a dual PI3K/mTOR inhibitor. The present invention also provides methods for determining whether a subject is a candidate for treatment, methods for evaluating the efficacy of treatment, and other methods, compositions, model systems, and assays.
    Type: Application
    Filed: April 27, 2020
    Publication date: January 14, 2021
    Inventors: Ingo Kai Mellinghoff, Sara Kubek
  • Platelet-derived growth factor receptor mutations and compositions and methods relating thereto
    Patent number: 10632121
    Abstract: In certain embodiments the present invention involves methods of killing tumor cells that comprise an oncogenic PDGFR mutation, and methods of treating subjects having tumors that comprise such tumor cells. In some embodiments such methods involve using PI3K inhibitors, or a combination of a PI3K inhibitor and an mTOR inhibitor, or a dual PI3K/mTOR inhibitor. The present invention also provides methods for determining whether a subject is a candidate for treatment, methods for evaluating the efficacy of treatment, and other methods, compositions, model systems, and assays.
    Type: Grant
    Filed: May 15, 2015
    Date of Patent: April 28, 2020
    Inventors: Ingo Kai Mellinghoff, Sara Kubek
  • PLATELET-DERIVED GROWTH FACTOR RECEPTOR MUTATIONS AND COMPOSITIONS AND METHODS RELATING THERETO
    Publication number: 20170087159
    Abstract: In certain embodiments the present invention involves methods of killing tumor cells that comprise an oncogenic PDGFR mutation, and methods of treating subjects having tumors that comprise such tumor cells. In some embodiments such methods involve using PI3K inhibitors, or a combination of a PI3K inhibitor and an mTOR inhibitor, or a dual PI3K/mTOR inhibitor. The present invention also provides methods for determining whether a subject is a candidate for treatment, methods for evaluating the efficacy of treatment, and other methods, compositions, model systems, and assays.
    Type: Application
    Filed: May 15, 2015
    Publication date: March 30, 2017
    Inventors: Ingo Kai Mellinghoff, Sara Kubek