Abstract: Double chamber container for holding and combining, e.g., a lyophilizate and a liquid reconstitution medium, comprising an integral cylindrical body (15) with a closure (20, 60) at each of the two ends (5, 70), an upper movable closure (60) to the side of the reconstitution medium and a lower closure (20) to the side of the lyophilizate, a separating stopper (40) that can be moved in the cylindrical body (15) as a seal between the upper chamber (50) and the lower chamber (30), a bypass (35), arranged below the separating stopper (40), having a length L greater than the height H of the separating stopper (40), wherein at the lower end (5) in the wall of the cylindrical body (15) or in the lower stopper (20) there are provided means (21, 25, 28) that allow connection of the interior of the cylindrical body (15) to the environment during the lyophilization.

Abstract: A double chamber container for holding and combining a solid lyophilizate and a liquid reconstituting medium, comprising a cylindrical body with a closure at each of the two ends, an upper displaceable closure at the reconstituting medium end, and a lower closure at the lyophilizate end, a separating stopper that can be pushed in the cylindrical body and act as a seal between the upper chamber and the lower chamber, and a bypass arranged underneath the separating stopper, with a length L that is preferably greater than the height H of the separating stopper, wherein at the upper end in the wall of the cylindrical body or in the separating stopper means are provided that allow partial connection of the interior of the cylindrical body to the environment during the lyophilization.

Abstract: The invention relates to a double chamber container for holding and combining two separate components, at least one of which is liquid, comprising a cylindrical body (15) with a closure (20, 60) at each of the two ends (5, 70) of the body (15), an upper closure (60) at the liquid component end and a lower closure (20) at the solid component end, and a separating stopper (40) in the cylindrical body (15) as a seal between the two chambers (30, 50), the separating stopper (40) having a height H and the upper closure (60) at the liquid component end being movable by the application of pressure, and comprising on its underside a hollow needle (45) with a length L having at least one opening (42) which is provided at the end opposite the tip, where H <L.

Abstract: A double chamber container for holding and combining a solid lyophilizate and a liquid reconstituting medium, comprising a cylindrical body (15) with a closure (20, 60) at each of the two ends (5, 70), an upper displaceable closure at the reconstituting medium end, and a lower closure (20) at the lyophilizate end, a separating stopper (40) that can be pushed in the cylindrical body (15) and act as a seal between the upper chamber (50) and the lower chamber 30), and a bypass (35) arranged underneath the separating stopper (40), with a length L that is preferably greater than the height H of the separating stopper (40), wherein at the upper end (70) in the wall of the cylindrical body (15) or in the separating stopper (40) means (75, 45) are provided that allow partial connection of the interior of the cylindrical body (15) to the environment during the lyophilization.

Abstract: The invention relates to a double chamber container for holding and combining two separate components, at least one of which is liquid, comprising a cylindrical body (15) with a closure (20, 60) at each end (5, 70), of which the closure (60) at the end of a chamber containing the liquid component (50) can be pushed, and a separating stopper (40) which can only be pushed by increased pressure, which is mounted in the cylindrical body (15), which defines the volume of the chamber (30, 50) mounted above and below, as a seal between the two chambers (30, 50), with an opening (42) running therethrough along its longitudinal axis, said opening having an upper part (42a) to the side of the chamber containing the liquid component (50) that is closed off in fluid-tight manner by a shaped member that is movable by gentle to moderate pressure (45).

Abstract: The invention relates to a double chamber container for holding and combining two separate components, at least one of which is liquid, comprising a cylindrical body (15) with a closure (20, 60) at each of the two ends (5, 70) of the body (15), an upper closure (60) at the liquid component end and a lower closure (20) at the solid component end, and a separating stopper (40) in the cylindrical body (15) as a seal between the two chambers (30, 50), the separating stopper (40) having a height H and the upper closure (60) at the liquid component end being movable by the application of pressure, and comprising on its underside a hollow needle (45) with a length L having at least one opening (42) which is provided at the end opposite the tip, where H<L.

Abstract: Double chamber container for holding and combining, e.g., a lyophilizate and a liquid reconstitution medium, comprising an integral cylindrical body (15) with a closure (20, 60) at each of the two ends (5, 70), an upper movable closure (60) to the side of the reconstitution medium and a lower closure (20) to the side of the lyophilizate, a separating stopper (40) that can be moved in the cylindrical body (15) as a seal between the upper chamber (50) and the lower chamber (30), a bypass (35), arranged below the separating stopper (40), having a length L greater than the height H of the separating stopper (40), wherein at the lower end (5) in the wall of the cylindrical body (15) or in the lower stopper (20) there are provided means (21, 25, 28) that allow connection of the interior of the cylindrical body (15) to the environment during the lyophilization.