Abstract: The present invention relates to biocompatible non-woven fibrous materials having a nano-micro topography and methods for producing such materials. The materials may be used to cover implantable medical devices and to fabricate a three-dimensional drug-eluting fibrous matrix featuring accurate spatial positioning of the drug particles within the matrix.

Abstract: This invention relates to a method to produce reproducible and homogeneous coatings and to fine-tune the coating morphology. More particularly, the invention relates to a method and apparatus for controlling the particle formation and deposition process to form a biocompatible coating on a medical implant or a tissue.

Abstract: A holding device and method is provided for efficiently applying a coating on the exterior surface of a tubular hollow body, while preventing coating application on the interior surface and coating defects. The holding device of the present invention comprises at least two structures contacting the inner surface of the tubular hollow body and extending to a portion where the structures are connected and rotary motion is induced to rotate the tubular hollow body. The structures are arranged and shaped so that an inner hollow section is formed in which excess coating material can accumulate.

Abstract: This invention relates to a multi-purpose holding device to handle, support and rotate one or more hollow cylindrical objects. The holding device consists of a rigid frame and support members for precise alignment and rotation of one or more objects within the frame structure. A method is also provided to reproducibly support, rotate and inspect the hollow cylindrical objects.

Abstract: A holding device and method is provided for efficiently applying a coating on the exterior surface of a tubular hollow body, while preventing coating application on the interior surface and coating defects. The holding device of the present invention comprises at least two structures contacting the inner surface of the tubular hollow body and extending to a portion where the structures are connected and rotary motion is induced to rotate the tubular hollow body. The structures are arranged and shaped so that an inner hollow section is formed in which excess coating material can accumulate.

Abstract: This invention relates to a multi-purpose holding device to handle, support and rotate one or more hollow cylindrical objects. The holding device consists of a rigid frame and support members for precise alignment and rotation of one or more objects within the frame structure. A method is also provided to reproducibly support, rotate and inspect the hollow cylindrical objects.

Abstract: The invention provides a precision spraying device having an improved atomizing end for reproducibly forming droplets from small amounts of liquid with improved operational stability and spray pattern quality as well as a method of manufacturing. The invention further provides a method for reproducibly coating substrates using the spraying device of the present invention.

Abstract: The purpose of the invention is to provide a method to characterize a spray pattern by detecting and quantifying asymmetries resulting in detailed information on location, size, and type of asymmetries within the spray pattern, which are important for spray characterization comparability and classification. A system is provided for in-situ monitoring of the spray characteristics.