Abstract: Disclosed is a holder, attachable to a receptacle, with a hollow spike for piercing the membrane of the receptacle and with a connection piece arranged coaxially to the hollow spike for the releasable attachment of an injection syringe. For the quick and secure withdrawal of a liquid medicament from the receptacle whilst maintaining sterility demands the holder is formed as a closed-walled protective housing which accommodates the receptacle and which comprises a first housing part carrying the receptacle secured in position and a second housing part provided in its inside with the hollow spike and on the outside comprising the connection piece. The second housing part is coaxially movable relative to the first housing part between a position-secured initial position in which the hollow spike is distanced from the membrane and a working position in which the membrane is pierced through the hollow spike.