Patents by Inventor Ingrid E. Akerblom
Ingrid E. Akerblom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20020064792Abstract: The present invention is a computerized storage and retrieval system for genetic information and related annotated information. The data of the system is stored in a relational database which interfaces with public databases to allow analysis both within the database of the invention and between information within that database and external public databases. The sequence data is edited before entry into the system, and is stored in a curated, functional clustering organization. The information associated with the data is stored in an expression database that is linked to the storage of the sequence data.Type: ApplicationFiled: September 19, 2001Publication date: May 30, 2002Inventors: Stephen E. Lincoln, Tod M. Klingler, Janice Au-Young, Y. Tom Tang, Richard D. Goold, Ingrid E. Akerblom, Jeffrey J. Seilhamer, Phillip R. Hawkins, Lynn E. Murry, Angelo M. Delegeane, Wendy B. Levine, Jennifer L. Hillman, Surya K. Goli, Christina M. Altus, Olga Bandman, Samuel T. LaBrie, Purvi Shah
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Patent number: 6363399Abstract: Disclosed is a relational database system for storing biomolecular sequence information in a manner that allows sequences to be catalogued and searched according to association with one or more projects for obtaining full-length biomolecular sequences from shorter sequences. The relational database has sequence records containing information identifying one or more projects to which each of the sequence records belong. Each project groups together one or more biomolecular sequences generated during work to obtain a full-length gene sequence from a shorter sequence. The computer system has a user interface allowing a user to selectively view information regarding one or more projects. The relational database also provides interfaces and methods for accessing and manipulating and analyzing project-based information.Type: GrantFiled: January 3, 2001Date of Patent: March 26, 2002Assignee: Incyte Genomics, Inc.Inventors: Timothy J. Maslyn, Janice Au-Young, Jennifer L. Hillman, Harold Hibbert, Ingrid E. Akerblom, Rachel J. Cheng, Yuanhua T. Tang
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Patent number: 6303297Abstract: The present invention is a computerized storage and retrieval system for genetic information and related annotated information. The data of the system is stored in a relational database which interfaces with public databases to allow analysis both within the database of the invention and between information within that database and external public databases. The sequence data is edited before entry into the system, and is stored in a curated, functional clustering organization. The information associated with the data is stored in an expression database that is linked to the storage of the sequence data.Type: GrantFiled: November 13, 1997Date of Patent: October 16, 2001Assignee: Incyte Pharmaceuticals, Inc.Inventors: Steve E. Lincoln, Tod M. Klingler, Janice Au-Young, Y. Tom Tang, Richard D. Goold, Ingrid E. Akerblom, Jeffrey J. Seilhamer, Phillip R. Hawkins, Lynn E. Murry, Angelo M. Delegeane, Wendy B. Levine, Jennifer L. Hillman, Surya K. Goli, Christina M. Altus, Olga Bandman, Samuel T. LaBrie, Purvi Shah
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Patent number: 6189013Abstract: Disclosed is a relational database system for storing biomolecular sequence information in a manner that allows sequences to be catalogued and searched according to association with one or more projects for obtaining full-length biomolecular sequences from shorter sequences. The relational database has sequence records containing information identifying one or more projects to which each of the sequence records belong. Each project groups together one or more biomolecular sequences generated during work to obtain a full-length gene sequence from a shorter sequence. The computer system has a user interface allowing a user to selectively view information regarding one or more projects. The relational database also provides interfaces and methods for accessing and manipulating and analyzing project-based information.Type: GrantFiled: June 24, 1999Date of Patent: February 13, 2001Assignee: Incyte Genomics, Inc.Inventors: Timothy J. Maslyn, Janice Au-Young, Jennifer L. Hillman, Harold Hibbert, Ingrid E. Akerblom, Rachel J. Cheng, Yuanhua T. Tang
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Patent number: 6143867Abstract: The present invention provides a human eosinophil-derived basic protein (EBPH) and polynucleotides which identify and encode EBPH. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding EBPH and a method for producing EBPH. The invention also provides for use of EBPH and agonists, antibodies or antagonists specifically binding EBPH, in the prevention and treatment of diseases associated with expression of EBPH. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding EBPH for the treatment of diseases associated with the expression of EBPH. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding EBPH.Type: GrantFiled: March 17, 1998Date of Patent: November 7, 2000Assignee: Incyte Pharmaceuticals, Inc.Inventor: Ingrid E. Akerblom
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Patent number: 6023659Abstract: Disclosed is a relational database system for storing biomolecular sequence information in a manner that allows sequences to be catalogued and searched according to one or more protein function hierarchies. The hierarchies allow searches for sequences based upon a protein's biological function or molecular function. Also disclosed is a mechanism for automatically grouping new sequences into protein function hierarchies. This mechanism uses descriptive information obtained from "external hits" which are matches of stored sequences against gene sequences stored in an external database such as GenBank. The descriptive information provided with the external database is evaluated according to a specific algorithm and used to automatically group the external hits (or the sequences associated with the hits) in the categories.Type: GrantFiled: March 6, 1997Date of Patent: February 8, 2000Assignee: Incyte Pharmaceuticals, Inc.Inventors: Jeffrey J. Seilhamer, Ingrid E. Akerblom, Christina M. Altus, Tod M. Klingler, Frank Russo, Janice Au-Young, Jennifer L. Hillman, Timothy J. Maslyn
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Patent number: 5998165Abstract: The present invention provides polynucleotides and related reagents which are associated with pancreatic and other cancers. These polynucleotides are designated PANC1A.Type: GrantFiled: March 15, 1996Date of Patent: December 7, 1999Assignee: Incyte Pharmaceuticals, Inc.Inventors: Richard D. Goold, Ingrid E. Akerblom, Jeffrey J. Seilhamer, Roger Coleman
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Patent number: 5962232Abstract: The invention provides human protein kinase molecules (HPKM) and polynucleotides which identify and encode HPKM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HPKM.Type: GrantFiled: January 30, 1998Date of Patent: October 5, 1999Assignee: Incyte Pharmaceuticals, Inc.Inventors: Olga Bandman, Jennifer L. Hillman, Preeti Lal, Ingrid E. Akerblom, Purvi Shah, Neil C. Corley, Karl J. Guegler
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Patent number: 5953727Abstract: Disclosed is a relational database system for storing biomolecular sequence information in a manner that allows sequences to be catalogued and searched according to association with one or more projects for obtaining full-length biomolecular sequences from shorter sequences. The relational database has sequence records containing information identifying one or more projects to which each of the sequence records belong. Each project groups together one or more biomolecular sequences generated during work to obtain a full-length gene sequence from a shorter sequence. The computer system has a user interface allowing a user to selectively view information regarding one or more projects. The relational database also provides interfaces and methods for accessing and manipulating and analyzing project-based information.Type: GrantFiled: March 6, 1997Date of Patent: September 14, 1999Assignee: Incyte Pharmaceuticals, Inc.Inventors: Timothy J. Maslyn, Janice Au-Young, Jennifer L. Hillman, Harold Hibbert, Ingrid E. Akerblom, Rachel J. Cheng, Yuanhua T. Tang
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Patent number: 5874535Abstract: The present invention provides a polynucleotide which identifies and encodes a novel human leptin receptor gene-related protein (LRGRP). The invention also provides expression vectors, host cells, agonists, and antagonists. The invention also provides methods for treating metabolic, reproductive, connective tissue and reproductive disorders.Type: GrantFiled: April 15, 1997Date of Patent: February 23, 1999Assignee: Incyte Pharmaceuticals, Inc.Inventors: Bernard Bailleul, A. Donny Strosberg, Ingrid E. Akerblom
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Patent number: 5840870Abstract: The present invention provides polynucleotide sequences designated PANC1A and PANC1B which are associated with a genomic sequence related to pancreatic cancer as well as other cancers. The present invention also provides for PANC1A and PANC1B antisense molecules. The invention further provides genetically engineered expression vectors and host cells for the production of purified PANC1A and PANC1B polypeptide; antibodies, antagonists and inhibitors of PANC1A and PANC1B polypeptide; and pharmaceutical compositions and methods of treatment based on the polypeptide, its antibodies, antagonists and inhibitors. The invention specifically provides for use of the polypeptide as a diagnostic composition for the detection of pancreatic cancer in individuals at risk for and subject to pancreatic cancer. The invention also relates to therapeutic methods and compositions based upon the nucleotide sequences for PANC1A and PANC1B.Type: GrantFiled: December 29, 1995Date of Patent: November 24, 1998Assignee: Incyte Pharmaceuticals, Inc.Inventors: Richard D. Goold, Ingrid E. Akerblom, Jeffrey J. Seilhamer
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Patent number: 5789198Abstract: The present invention provides a polynucleotide which identifies and encodes a novel human leptin receptor-related protein (LRRP). The invention provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequence encoding LRRP.Type: GrantFiled: August 1, 1996Date of Patent: August 4, 1998Assignee: Incyte Pharmaceuticals, Inc.Inventor: Ingrid E. Akerblom
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Patent number: 5728820Abstract: The present invention provides a human eosinophil-derived basic protein (EBPH) and polynucleotides which identify and encode EBPH. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding EBPH and a method for producing EBPH. The invention also provides for use of EBPH and agonists, antibodies or antagonists specifically binding EBPH, in the prevention and treatment of diseases associated with expression of EBPH. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding EBPH for the treatment of diseases associated with the expression of EBPH. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding EBPH.Type: GrantFiled: October 23, 1996Date of Patent: March 17, 1998Assignee: Incyte Pharmaceuticals, Inc.Inventor: Ingrid E. Akerblom