Patents by Inventor Inmin Wu

Inmin Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antiangiogenic peptides and compositions thereof
    Patent number: 6737507
    Abstract: The present invention provides an antiangiogenic polypeptide having the amino acid sequence set forth in SEQ ID NO: 1 or a portion thereof which is effective to inhibit endothelial cell proliferation as determined by the capillary EC proliferation assay. Preferably, the portion has at least 50% inhibition of bFGF-stimulated EC proliferation at 5 Tg/ml, more preferably 75% inhibition, most preferably 95% inhibition.
    Type: Grant
    Filed: September 18, 2001
    Date of Patent: May 18, 2004
    Assignee: Children's Medical Center Corporation
    Inventors: Marsha Moses, Inmin Wu, Cecilia Fernandez
  • Pharmaceutical compositions comprising troponin subunits, fragments and analogs thereof and methods of their use to inhibit angiogenesis
    Patent number: 6653283
    Abstract: Pharmaceutical compositions and methods of treatment of diseases or disorders involving angiogenesis with therapeutically effective amounts of troponin C, I, or T, subunits, fragments, or analogs thereof.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: November 25, 2003
    Assignee: Children's Medical Center Corporation
    Inventors: Marsha A. Moses, Robert S. Langer, Dimitri G. Wiederschain, Inmin Wu, Arthur Sytkowski
  • Novel antiangiogenic peptides
    Publication number: 20020086420
    Abstract: The present invention provides an antiangiogenic polypeptide having the amino acid sequence set forth in SEQ ID NO: 1 or a portion thereof which is effective to inhibit endothelial cell proliferation as determined by the capillary EC proliferation assay. Preferably, the portion has at least 50% inhibition of bFGF-stimulated EC proliferation at 5 Tg/ml, more preferably 75% inhibition, most preferably 95% inhibition.
    Type: Application
    Filed: September 18, 2001
    Publication date: July 4, 2002
    Applicant: Children's Medical Center Corporation
    Inventors: Marsha Moses, Inmin Wu, Cecilia Fernandez
  • Pharmaceutical compositions comprising troponin subunits, fragments and analogs thereof and methods of their use to inhibit angiogenesis
    Patent number: 6403558
    Abstract: Pharmaceutical compositions and methods of treatment of diseases or disorders involving angiogenesis with therapeutically effective amounts of troponin C, I, or T, subunits, fragments, or analogs thereof.
    Type: Grant
    Filed: August 4, 1999
    Date of Patent: June 11, 2002
    Assignee: Children's Medical Center Corporation
    Inventors: Marsha A. Moses, Robert S. Langer, Dimitri G. Wiederschain, Inmin Wu, Arthur Sytkowski
  • Pharmaceutical compositions comprising troponin subunits, fragments and analogs thereof and methods of their use to inhibit angiogenesis
    Patent number: 6025331
    Abstract: Pharmaceutical compositions containing therapeutically effective amounts of troponin C, I, or T, subunits, fragments, or analogs for the treatment of diseases or disorders involving abnormal angrogenesis.
    Type: Grant
    Filed: October 30, 1997
    Date of Patent: February 15, 2000
    Assignee: Children's Medical Center Corporation
    Inventors: Marsha A. Moses, Robert S. Langer, Dimitri G. Wiederschain, Inmin Wu, Arthur Sytkowski
  • Pharmaceutical compositions comprising troponin subunits, fragments and analogs thereof and methods of their use to inhibit angiogenesis
    Patent number: 5837680
    Abstract: The present invention relates to pharmaceutical compositions containing troponin subunits C, I, or T, or fragments thereof, in therapeutically effective amounts that are capable of inhibiting endothelial cell proliferation. The invention also relates to pharmaceutical compositions containing analogs of troponin subunits C, I, or T and analogs of their fragments, in therapeutically effective amounts that are capable of inhibiting endothelial cell proliferation. The invention further relates to treatment of neovascular disorders by administration of a therapeutic compound of the invention.
    Type: Grant
    Filed: February 16, 1996
    Date of Patent: November 17, 1998
    Assignee: Children's Medical Center Corporation
    Inventors: Marsha A. Moses, Robert S. Langer, Dimitri G. Wiederschain, Inmin Wu, Arthur Sytkowski