Abstract: A system comprises an image capture device, an augmented reality (AR) display to display, and a processing device. The processing deice receives image data of a dental arch from the image capture device and processes the image data using a plurality of detection rules, where each detection rule detects one or more dental conditions. The processing device determines a dental condition for the dental arch based on the processing, determines a position of an area of interest on the dental arch, wherein the area of interest is associated with the dental condition, generates a visual overlay comprising an indication of the dental condition at the position of the area of interest, and outputs the visual overlay to the AR display, wherein the visual overlay is superimposed over a view of the dental arch on the AR display at the position of the area of interest.

Abstract: An image of a dental arch comprising a preparation tooth is generated by an image capture device associated with an augmented reality (AR) display. The image of the dental arch is registered to previous image data associated with the dental arch. A visual overlay associated with a dental prosthetic to be placed on the preparation tooth is generated based on the registering of the image of the dental arch to the previous image data associated with the dental arch. The visual overlay is output to the AR display, wherein the visual overlay is superimposed over a view of the preparation tooth on the AR display.

Abstract: A processing device receives, from an image capture device associated with an augmented reality (AR) display, a plurality of images of a face of a patient. The processing device selects a subset of the plurality of images that meet one or more image selection criteria. The selection comprises determining, from the plurality of images, a first image that represents a first position extreme for the face; determining, from the plurality of images, a second image that represents a second position extreme of the face; selecting the first image; and selecting the second image. The processing device further generates a model of a jaw of the patient based at least in part on the subset of the plurality of images that have been selected.

Abstract: A method of generating a 3D model includes: determining a 3D surface comprising a preparation tooth using a first plurality of intraoral scans generated by an intraoral scanner at a first time; receiving one or more additional intraoral scans of the preparation tooth that were generated by the intraoral scanner at a second time; determining a change to one or more portions of the preparation tooth between the three-dimensional surface and the one or more additional intraoral scans; determining, based at least in part on the change to the preparation tooth, whether to use a) the 3D surface, b) data from the one or more additional intraoral scans or c) a combination of the 3D surface and the data from the one or more additional intraoral scans to depict one or more portions of the preparation tooth; and generating the 3D model comprising the preparation tooth.

Abstract: A processing device may receive a plurality of intraoral scans of the patient that were generated by an intraoral scanner, determine a three-dimensional surface of at least a portion of one or more dental arch of the patient using the plurality of intraoral scans, automatically determine whether a restorative dental object is represented in at least one of the three-dimensional surface or one or more intraoral scans of the plurality of intraoral scans, and automatically generate a prescription for treating the one or more teeth based at least in part on at least one of a) a presence or absence of a restorative dental object in at least one of the three-dimensional surface or the one or more intraoral scans or b) a location of the restorative dental object in the one or more dental arch of the patient.

Abstract: A processing device receives a plurality of intraoral scans of a dental arch. The processing device determines, from the plurality of intraoral scans, a first set of intraoral scans that depict a restorative object and a second set of intraoral scans that fail to depict any restorative object. The processing device generates a multi-resolution three-dimensional model of the dental arch, wherein a first portion of the multi-resolution three-dimensional model is generated from the first set of intraoral scans, has a first resolution and represents the restorative object, and wherein a second portion of the multi-resolution three-dimensional model is generated from the second set of intraoral scans, has a second resolution and represents a remainder of the dental arch, wherein the first resolution is greater than the second resolution.

Abstract: A method of intraoral scanning includes receiving a first one or more intraoral scans of a patient's oral cavity; automatically determining, based on processing of the first one or more intraoral scans, a first scanning role associated with the first one or more intraoral scans, wherein the first scanning role is a first one of an upper dental arch role, a lower dental arch role or a bite role; and determining a first three-dimensional surface associated with the first scanning role.

Abstract: An image of a dental arch comprising a preparation tooth is generated by an image capture device associated with an augmented reality (AR) display. The image of the dental arch is registered to previous image data associated with the dental arch. A visual overlay associated with a dental prosthetic to be placed on the preparation tooth is generated based on the registering of the image of the dental arch to the previous image data associated with the dental arch. The visual overlay is output to the AR display, wherein the visual overlay is superimposed over a view of the preparation tooth on the AR display.

Abstract: A method of using AR for dentistry and orthodontics is provided. An image of a dental arch is received, the image having been generated by an image capture device associated with an augmented reality (AR) display. A processing device registers the image to previous image data associated with the dental arch, compares one or more areas of the dental arch from the image to one or more corresponding areas of the dental arch from the previous image data, determines a position of an area of interest on the dental arch based on the comparing, generates a visual overlay comprising an indication of the area of interest, and outputs the visual overlay to the AR display, wherein the visual overlay is superimposed over a view of the dental arch on the AR display at the position of the area of interest.

Abstract: A processing device receives, from an image capture device associated with an augmented reality (AR) display, a plurality of images of a face of a patient. The processing device selects a subset of the plurality of images that meet one or more image selection criteria. The selection comprises determining, from the plurality of images, a first image that represents a first position extreme for the face; determining, from the plurality of images, a second image that represents a second position extreme of the face; selecting the first image; and selecting the second image. The processing device further generates a model of a jaw of the patient based at least in part on the subset of the plurality of images that have been selected.

Abstract: A method of using AR for dentistry and orthodontics is provided. An image of a dental arch is received, the image having been generated by an image capture device associated with an augmented reality (AR) display. A processing device registers the image to previous image data associated with the dental arch, compares one or more areas of the dental arch from the image to one or more corresponding areas of the dental arch from the previous image data, determines a position of an area of interest on the dental arch based on the comparing, generates a visual overlay comprising an indication of the area of interest, and outputs the visual overlay to the AR display, wherein the visual overlay is superimposed over a view of the dental arch on the AR display at the position of the area of interest.

Abstract: Disclosed herein is a new route of synthesis and a new stable amorphous form of ibrutinib. Also disclosed are pharmaceutical compositions, oral dosage forms and the use of the amorphous ibrutinib in the treatment of mantle cell lymphoma or chronic lymphocytic leukemia.