Patents by Inventor Insoo Bae

Insoo Bae has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Boronic acid derivatives of resveratrol for activating deacetylase enzymes
    Patent number: 10478445
    Abstract: Disclosed herein are compounds, compositions and methods for the treatment of a disease or disorder related to activation of deacetylase enzymes. The compounds and methods are related to boronic acid derivatives of resveratrol. In some forms, the compound, compositions and methods relate to treatment of prostate cancer, colon cancer, or breast cancer, a cardiovascular disease, inflammation, obesity, diabetes, or a neurodegenerative disease.
    Type: Grant
    Filed: July 3, 2014
    Date of Patent: November 19, 2019
    Assignee: Georgetown University
    Inventors: Insoo Bae, Yong Weon Yi, Hyo Jin Kang, Hee Jeong Kim
  • BORONIC ACID DERIVATIVES OF RESVERATROL FOR ACTIVATING DEACETYLASE ENZYMES
    Publication number: 20160166592
    Abstract: Disclosed herein are compounds, compositions and methods for the treatment of a disease or disorder related to activation of deacetylase enzymes. The compounds and methods are related to boronic acid derivatives of resveratrol. In some forms, the compound, compositions and methods relate to treatment of prostate cancer, colon cancer, or breast cancer, a cardiovascular disease, inflammation, obesity, diabetes, or a neurodegenerative disease.
    Type: Application
    Filed: July 3, 2014
    Publication date: June 16, 2016
    Inventors: Insoo Bae, Yong Weon Yi, Hyo Jin Kang, Hee Jeong Kim
  • Method for treating rheumatoid arthritis with composition containing histone
    Publication number: 20030007964
    Abstract: The present invention relates to a novel use of histone and an active fragment thereof and provides a pharmaceutical composition containing histone as an active ingredient to improve the symptoms of progressive, inflammatory and autoimmune arthritis. The pharmaceutical composition of the present invention includes histone, especially histone H1, histone H2A, histone H2B, histone H3, histone H4, an active fragment thereof, and a mixture thereof as an active ingredient, and could include pharmacologically approved carriers if necessary. Histone or its active fragment lowered induction of arthritis and reduced arthritis index more effectively than steroidal dexamethasone and also had a significant preventive effect.
    Type: Application
    Filed: June 12, 2002
    Publication date: January 9, 2003
    Applicant: SAMYANG GENEX CORPORATION
    Inventors: Insoo Bae, Dong-soo Kim, Heajoon Yim, Neon-Cheol Jung, Yong-Weon Yi, Seung-Suh Hong, Hyun-Soo Lee
  • Method for treating rheumatoid arthritis with composition containing histone
    Patent number: 6204242
    Abstract: The present invention relates to a novel use of histone and provides a pharmaceutical composition containing histone as an active ingredient to improve the symptoms of progressive, inflammatory and autoimmune arthritis. The pharmaceutical composition of the present invention includes histone, especially histone H1 as an active ingredient, and could include pharmacologically approved carriers if necessary. Histone H1 lowered induction of arthritis and reduced arthritis index more effectively than steroidal dexamethasone and also had a significant preventive effect.
    Type: Grant
    Filed: January 19, 2000
    Date of Patent: March 20, 2001
    Assignee: Samyang Genex Corporation
    Inventors: Insoo Bae, Dong-soo Kim, Heajoon Yim, Neon-Cheol Jung, Yong-Weon Yi, Seung-Suh Hong, Hyun-Soo Lee