Patents by Inventor Insung Na

Insung Na has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Composition comprising compound inhibiting interactions of MBD2 and P66? for anti-metastasis and prevention and treatment of cancer disease
    Patent number: 10610514
    Abstract: The present invention relates to a composition including an inhibitor against the function of an Mi-2/NuRD chromatin remodeling complex for inhibiting metastasis and preventing and treating cancer diseases, and more particularly, the composition may inhibit the MBD2-p66? (GATAD2A) interaction by means of the Mi-2/NuRD CRC function inhibitor, and thus is expected to be effectively used as a composition capable of inhibiting metastasis and preventing and treating cancer diseases.
    Type: Grant
    Filed: November 24, 2017
    Date of Patent: April 7, 2020
    Assignees: Industry-University Cooperation Foundation Hanyang University, University of South Florida
    Inventors: Chul Geun Kim, Min Young Kim, Young Su Lim, Dae Hyun Ha, Young Yiul Lee, Buom Yong Ryu, Vladimir Uversky, Insung Na, Yu Chen, Arjan van der Vaart
  • METHOD OF DISCOVERING NEW DRUG CANDIDATE TARGETING DISORDER-TO-ORDER TRANSITION REGION AND APPARATUS FOR DISCOVERING NEW DRUG CANDIDATE
    Publication number: 20190279737
    Abstract: A method of discovering a drug candidate, comprising: a step in which a computer device uses bioinformatics to determine a disorder-to-order transition region of a target protein; a step in which the computer device performs molecular docking on the disorder-to-order transition region in conjunction with a library of specific compounds to select first candidate compounds capable of binding to the disorder-to-order transition region from among the compound library; and a step in which the computer device performs a molecular dynamics simulation for the first candidate compounds and the disorder-to-order transition region to select a second candidate compound from among the first candidate compounds.
    Type: Application
    Filed: November 24, 2017
    Publication date: September 12, 2019
    Applicant: INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY
    Inventors: Insung NA, Min Young KIM, Vladimir UVERSKY, Chul Geun KIM
  • COMPOSITION COMPRISING COMPOUND INHIBITING INTERACTIONS OF MBD2 AND P66A FOR ANTI-METASTASIS AND PREVENTION AND TREATMENT OF CANCER DISEASE
    Publication number: 20180250266
    Abstract: The present invention relates to a composition including an inhibitor against the function of an Mi-2/NuRD chromatin remodeling complex for inhibiting metastasis and preventing and treating cancer diseases, and more particularly, the composition may inhibit the MBD2-p66? (GATAD2A) interaction by means of the Mi-2/NuRD CRC function inhibitor, and thus is expected to be effectively used as a composition capable of inhibiting metastasis and preventing and treating cancer diseases.
    Type: Application
    Filed: November 24, 2017
    Publication date: September 6, 2018
    Applicant: Industry-University Cooperation Foundation Hanyang University
    Inventors: Chul Geun KIM, MINYOUNG KIM, Youngsu LIM, DAEHYUN HA, Young Yiul LEE, Buom Yong RYU, Vladimir Uversky, Insung Na, Yu Chen, Arjan van der Vaart