Patents by Inventor Inze Lin

Inze Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline form of ivacaftor and a process for preparing the same
    Patent number: 11384054
    Abstract: In certain aspects, the invention provides crystalline forms of ivacaftor N-(2,4-di-tert-butyl-phenyl-5-hydroxy-phenyl)-1,4-dihydro-4-oxoquinoline-3-carboxamide. In related aspects, the invention provides a process for preparing any one of crystalline forms S2, S3, S4 and S5 of ivacaftor. The process includes: forming a solution including crude ivacaftor and a solvent; adding an anti-solvent to the solution to form slurry including a precipitate; isolating the precipitate; and drying the precipitate to provide crystalline form S2, S3, S4, or S5 of ivacaftor.
    Type: Grant
    Filed: March 12, 2021
    Date of Patent: July 12, 2022
    Assignee: ScinoPharm Taiwan, Ltd.
    Inventors: Kuan-Hsun Huang, Li-Ting Wang, Inze Lin, Tsung-Cheng Hu
  • NOVEL CRYSTALLINE FORM OF IVACAFTOR AND A PROCESS FOR PREPARING THE SAME
    Publication number: 20220127234
    Abstract: In certain aspects, the invention provides crystalline forms of ivacaftor N-(2,4-di-tert-butyl-phenyl-5-hydroxy-phenyl)-1,4-dihydro-4-oxoquinoline-3-carboxamide. In related aspects, the invention provides a process for preparing any one of crystalline forms S2, S3, S4 and S5 of ivacaftor. The process includes: forming a solution including crude ivacaftor and a solvent; adding an anti-solvent to the solution to form slurry including a precipitate; isolating the precipitate; and drying the precipitate to provide crystalline form S2, S3, S4, or S5 of ivacaftor.
    Type: Application
    Filed: March 12, 2021
    Publication date: April 28, 2022
    Inventors: Kuan-Hsun HUANG, Li-Ting WANG, Inze LIN, Tsung-Cheng HU
  • Solid forms of 3-(4-amino-1-oxo-1,3-dihydro-isoindo1-2-yl)-piperidine-2,6-dione and methods of making the same
    Patent number: 8420672
    Abstract: The present invention provides for new crystalline and amorphous forms of 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione, and methods of making the same.
    Type: Grant
    Filed: September 17, 2010
    Date of Patent: April 16, 2013
    Assignee: ScinoPharm Taiwan Ltd.
    Inventors: Chen-Tung Chen, Inze Lin
  • Solid Forms of 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione and Methods of Making the Same
    Publication number: 20110065750
    Abstract: The present invention provides for new crystalline and amorphous forms of 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione, and methods of making the same.
    Type: Application
    Filed: September 17, 2010
    Publication date: March 17, 2011
    Applicant: ScinoPharm Taiwan Ltd.
    Inventors: Chen-Tung CHEN, Inze Lin