Abstract: This invention refers to a method of withholding noxious compounds contained in cigarette smoke (NO, NOx, carcinogenic nitrosocompounds, free radicals, H.sub.2 O.sub.2, CO, aldehydes, and trace elements) which were up to today insufficiently retained by conventional cigarette filters. The method described specifically refers to the enrichment of common convention filters with biological substances of the metal ions (Fe.sup.2+, Cu.sup.2+, Mg.sup.2+) complexed with porphirin ring as well as Fe.sup.2+ ions stereospecifically bound to protein molecules, either separately or in combinations. The enrichment of these conventional filters with the abovementioned biological substances alters neither the physical properties of the cigarette smoke (odor, taste and appearance) nor the physical properties of the filter itself.