Patents by Inventor Ion A. Hobai

Ion A. Hobai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for treating heart failure by inhibiting the sarcolemmal sodium/calcium exchange
    Publication number: 20100184691
    Abstract: The present invention discloses a method of enhancing cardiac contractility in a subject with heart failure. The method consists of administering a compound that inhibits the sarcolemmal sodium/calcium exchanger, whose activity is elevated in heart failure. This method results in correction of cellular calcium handling and enhancement of cardiac contractility to healthy levels. This method can be used for treatment of acute heart failure, cardiogenic shock and congestive heart failure.
    Type: Application
    Filed: August 18, 2006
    Publication date: July 22, 2010
    Inventors: Ion A. Hobai, Brian O'Rourke
  • Method for treating heart failure by inhibiting the sarcolemmal sodium/calcium exchange
    Patent number: 7109169
    Abstract: The present invention discloses a method of enhancing cardiac contractility in a subject with heart failure. The method consists of administering a compound that inhibits the sarcolemmal sodium/calcium exchanger, whose activity is elevated in heart failure. This method results in correction of cellular calcium handling and enhancement of cardiac contractility to healthy levels. This method can be used for treatment of acute heart failure, cardiogenic shock and congestive heart failure.
    Type: Grant
    Filed: June 30, 2003
    Date of Patent: September 19, 2006
    Inventors: Ion A. Hobai, Brian O'Rourke
  • Method for treating heart failure by inhibiting the sarcolemmal sodium/calcium exchange
    Publication number: 20040009894
    Abstract: The present invention discloses a method of enhancing cardiac contractility in a subject with heart failure. The method consists of administering a compound that inhibits the sarcolemmal sodium/calcium exchanger, whose activity is elevated in heart failure. This method results in correction of cellular calcium handling and enhancement of cardiac contractility to healthy levels. This method can be used for treatment of acute heart failure, cardiogenic shock and congestive heart failure.
    Type: Application
    Filed: June 30, 2003
    Publication date: January 15, 2004
    Inventors: Ion A. Hobai, Brian O'Rouke