Patents by Inventor Iori Itagaki

Iori Itagaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-containing five-membered ring compounds and pharmaceutical agents comprising the same as active ingredient
    Patent number: 7390804
    Abstract: An N-containing five-membered ring compound of formula (I) wherein all symbols are the same as described in the specification, and a non-toxic salt thereof. The compound of formula (I) has an inhibitory activity against cysteine protease and therefore it is useful as an agent for the prophylaxis and/or treatment of inflammatory diseases, diseases induced by apoptosis, diseases induced by disorders of immune responses, autoimmune diseases, diseases induced by decomposition of proteins which compose organism, shock, circulatory system disorders, blood coagulation systems disorders, malignant tumors, acquired immune deficiency syndrome (AIDS) and AIDS-related complex (ARC), parasitic diseases, nerve degeneration diseases, pulmonary disorders, bone resorption diseases, endocrinesthenia, etc.
    Type: Grant
    Filed: December 22, 2004
    Date of Patent: June 24, 2008
    Assignee: Ono Pharmaceutical Co., Ltd.
    Inventors: Kazuyuki Ohmoto, Iori Itagaki
  • Oxadiazole derivatives and drugs containing these derivatives as the active ingredient
    Publication number: 20070004642
    Abstract: An oxadiazole derivative of formula (I) and a non-toxic salt thereof, wherein R is hydrogen, alkyl, CycA, etc.; AA1 is a single bond, amino acid residue, etc.; AA2 is a single bond, amino acid residue, etc.; R7 and R8 are hydrogen, alkyl, etc.; R9 is hydrogen, alkyl, etc.; R10 is hydrogen, alkyl, etc.). The compound of formula (I) has an inhibitory activity against cysteine protease and therefore it is useful as an agent for the prophylaxis and/or treatment of inflammatory diseases, diseases induced by apoptosis, diseases induced by disorders of immune responses, autoimmune diseases, diseases induced by decomposition of proteins which compose organism, shock, circulatory system disorders, blood coagulation system disorders, malignant tumors, acquired immune deficiency syndrome (AIDS) and AIDS-related complex (ARC), parasitic diseases, nerve degeneration diseases, pulmonary disorders, bone resorption diseases, endocrinesthenia, etc.
    Type: Application
    Filed: July 19, 2006
    Publication date: January 4, 2007
    Inventors: Kazuyuki Ohmoto, Iori Itagaki
  • Oxadiazole derivatives and drugs containing these derivatives as the active ingredient
    Patent number: 7144901
    Abstract: An oxadiazole derivative of formula (I) and a non-toxic salt thereof, wherein R is hydrogen, alkyl, CycA, etc.; AA1 is a single bond, amino acid residue, etc.; AA2 is a single bond, amino acid residue, etc.; R7 and R8 are hydrogen, alkyl, etc.; R9 is hydrogen, alkyl, etc. R10 is hydrogen, alkyl, etc.).
    Type: Grant
    Filed: December 1, 2000
    Date of Patent: December 5, 2006
    Assignee: ONO Pharmaceutical Co.,Ltd.
    Inventors: Kazuyuki Ohmoto, Iori Itagaki
  • Benzene-fused heteroring derivatives and pharmaceutical agents comprising the same as active ingredient
    Patent number: 7008938
    Abstract: A benzene-fused heteroring derivative of formula (I) wherein all symbols are the same as described in the specification, and a non-toxic salt thereof. The compound of formula (I) has an inhibitory activity against cysteine protease and therefore it is useful as an agent for the prophylaxis and/or treatment of immune diseases (autoimmune diseases, infectious diseases, etc.), inflammatory diseases (inflammatory bowel diseases, multiple cerebrosclerosis, arthritis, etc.), nerve degeneration diseases (Alzheimer's disease, muscular dystrophy, etc.), bone resorption diseases (osteoporosis, etc.), respiratory system diseases, diabetes, shock, etc.
    Type: Grant
    Filed: July 29, 2004
    Date of Patent: March 7, 2006
    Assignee: Nokia Corporation
    Inventors: Kazuyuki Ohmoto, Iori Itagaki
  • N-containing five-membered ring compounds and pharmaceutical agents comprising the same as active ingredient
    Publication number: 20050164954
    Abstract: An N-containing five-membered ring compound of formula (I) wherein all symbols are the same as described in the specification, and a non-toxic salt thereof. The compound of formula (I) has an inhibitory activity against cysteine protease and therefore it is useful as an agent for the prophylaxis and/or treatment of inflammatory diseases, diseases induced by apoptosis, diseases induced by disorders of immune responses, autoimmune diseases, diseases induced by decomposition of proteins which compose organism, shock, circulatory system disorders, blood coagulation systems disorders, malignant tumors, acquired immune deficiency syndrome (AIDS) and AIDS-related complex (ARC), parasitic diseases, nerve degeneration diseases, pulmonary disorders, bone resorption diseases, endocrinesthenia, etc.
    Type: Application
    Filed: December 22, 2004
    Publication date: July 28, 2005
    Inventors: Kazuyuki Ohmoto, Iori Itagaki
  • N-containing five-membered ring compounds and pharmaceutical agents comprising the same as active ingredient
    Patent number: 6900207
    Abstract: An N-containing five-membered ring compound of formula (I) wherein all symbols are the same as described in the specification, and a non-toxic salt thereof. The compound of formula (I) has an inhibitory activity against cysteine protease and therefore it is useful as an agent for the prophylaxis and/or treatment of inflammatory diseases, diseases induced by apoptosis, diseases induced by disorders of immune responses, autoimmune diseases, diseases induced by decomposition of proteins which compose organism, shock, circulatory system disorders, blood coagulation systems disorders, malignant tumors, acquired immune deficiency syndrome (AIDS) and AIDS-related complex (ARC), parasitic diseases, nerve degeneration diseases, pulmonary disorders, bone resorption diseases, endocrinesthenia, etc.
    Type: Grant
    Filed: January 25, 2001
    Date of Patent: May 31, 2005
    Assignee: Ono Pharmaceutical Co., Ltd.
    Inventors: Kazuyuki Ohmoto, Iori Itagaki
  • Benzene-fused heteroring derivatives and pharmaceutical agents comprising the same as active ingredient
    Publication number: 20050009755
    Abstract: A benzene-fused heteroring derivative of formula (I) wherein all symbols are the same as described in the specification, and a non-toxic salt thereof. The compound of formula (I) has an inhibitory activity against cysteine protease and therefore it is useful as an agent for the prophylaxis and/or treatment of immune diseases (autoimmune diseases, infectious diseases, etc.), inflammatory diseases (inflammatory bowel diseases, multiple cerebrosclerosis, arthritis, etc.), nerve degeneration diseases (Alzheimer's disease, muscular dystrophy, etc.), bone resorption diseases (osteoporosis, etc.), respiratory system diseases, diabetes, shock, etc.
    Type: Application
    Filed: July 29, 2004
    Publication date: January 13, 2005
    Inventors: Kazuyuki Ohmoto, Iori Itagaki
  • Benezene-fused heteroring derivatives and pharmaceutical agents comprising the same as active ingredient
    Patent number: 6809092
    Abstract: A benzene-fused heteroring derivative of formula (I) wherein all symbols are the same as described in the specification, and a non-toxic salt thereof. The compound of formula (I) has an inhibitory activity against cysteine protease and therefore it is useful as an agent for the prophylaxis and/or treatment of immune diseases (autoimmune diseases, infectious diseases, etc.), inflammatory diseases (inflammatory bowel diseases, multiple cerebrosclerosis, arthritis, etc.), nerve degeneration diseases (Alzheimer's disease, muscular dystrophy, etc.), bone resorption diseases (osteoporosis, etc.), respiratory system diseases, diabetes, shock, etc.
    Type: Grant
    Filed: July 22, 2002
    Date of Patent: October 26, 2004
    Assignee: Ono Pharmaceutical Co., Ltd.
    Inventors: Kazuyuki Ohmoto, Iori Itagaki
  • 1,3,4-oxadiazoline derivative and an agent comprising its derivative as active ingredient
    Patent number: 6797720
    Abstract: A 1,3,4-oxadiazoline derivative of formula (I) wherein W is oxygen, sulfer; R is hydrogen, alkyl, CycA, etc.; AA1 is a single bond, amino acid residue, etc.; AA2 is a single bond, amino acid residue, etc.; R7 and R8 are hydrogen, alkyl, etc.; R9 is hydrogen, alkyl, etc., and a non-toxic salt thereof. The compound of formula (I) has an inhibitory activity against cysteine protease and therefore it is useful as an agent for the prophylaxis and/or treatment of inflammatory diseases, diseases induced by apoptosis, diseases induced by disorders of immune responses, autoimmune diseases, diseases induced by decomposition of proteins which compose organism, shock, circulatory system disorders, blood coagulation systems disorders, malignant tumors, acquired immune deficiency syndrome (AIDS) and AIDS-related complex (ARC), parasitic diseases, nerve degeneration diseases, pulmonary disorders, bone resorption diseases, endocrinesthenia, etc.
    Type: Grant
    Filed: August 28, 2002
    Date of Patent: September 28, 2004
    Assignee: ONO Pharmaceutical Co., Ltd.
    Inventors: Kazuyuki Ohmoto, Iori Itagaki
  • 1,3,4-Oxadiazoline derivatives and drugs containing these derivatives as active ingredient
    Publication number: 20030166574
    Abstract: A 1,3,4-oxadiazoline derivative of formula (I) 1
    Type: Application
    Filed: August 28, 2002
    Publication date: September 4, 2003
    Inventors: Kazuyuki Ohmoto, Iori Itagaki
  • Oxadiazole derivatives and drugs containing these derivatives as the active ingredient
    Publication number: 20030166573
    Abstract: An oxadiazole derivative of formula (I) and a non-toxic salt thereof, 1
    Type: Application
    Filed: August 21, 2002
    Publication date: September 4, 2003
    Inventors: Kazuyuki Ohmoto, Iori Itagaki
  • Benzene-fused heterocycle derivatives and drugs containing the same as the active ingredient
    Publication number: 20030162964
    Abstract: A benzene-fused heteroring derivative of formula (I) 1
    Type: Application
    Filed: July 22, 2002
    Publication date: August 28, 2003
    Inventors: Kazuyuki Ohmoto, Iori Itagaki
  • Nitrogen-containing 5-membered cyclic compounds and drugs containing these compounds as the active ingredient
    Publication number: 20030153508
    Abstract: An N-containing five-membered ring compound of formula (I) 1
    Type: Application
    Filed: July 23, 2002
    Publication date: August 14, 2003
    Inventors: Kazuyuki Ohmoto, Iori Itagaki