Patents by Inventor Iossif A. Strehin

Iossif A. Strehin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COACERVATE HYALURONAN HYDROGELS FOR DERMAL FILLER APPLICATIONS
    Publication number: 20240316246
    Abstract: The present disclosure provides dermal fillers comprising hyaluronic acid-based hydrogels. The hydrogels are coacervates formed through ionic interactions between anionic polysaccharides, such as hyaluronic acid, and cationic polysaccharides, such as chitosan. The dermal fillers are useful for augmenting soft tissues, reducing soft tissue defects and improving skin quality.
    Type: Application
    Filed: December 27, 2023
    Publication date: September 26, 2024
    Inventors: Futian Liu, Xiaojie Yu, Dennis E. Van Epps, Iossif A. Strehin
  • COACERVATE HYALURONAN HYDROGELS FOR DERMAL FILLER APPLICATIONS
    Publication number: 20230277725
    Abstract: The present disclosure provides dermal fillers comprising hyaluronic acid-based hydrogels. The hydrogels are coacervates formed through ionic interactions between anionic polysaccharides, such as hyaluronic acid, and cationic polysaccharides, such as chitosan. The dermal fillers are useful for augmenting soft tissues, reducing soft tissue defects and improving skin quality.
    Type: Application
    Filed: October 11, 2022
    Publication date: September 7, 2023
    Inventors: Futian Liu, Xiaojie Yu, Dennis E. Van Epps, Iossif A. Strehin
  • Epimorphic regeneration and related hydrogel delivery systems
    Patent number: 11033541
    Abstract: Methods and compositions are described for enhancing tissue regeneration or wound repair in a mammalian subject comprising a composition comprising (a) a proline hydroxylase inhibitor component or molecule that increases or upregulates HIF1a and (b) a carrier component comprising a hydrogel.
    Type: Grant
    Filed: June 3, 2019
    Date of Patent: June 15, 2021
    Assignees: Northwestern University, The Wistar Institute of Anatomy and Biology
    Inventors: Phillip B. Messersmith, Iossif A. Strehin, Ellen Heber-Katz
  • COACERVATE HYALURONAN HYDROGELS FOR DERMAL FILLER APPLICATIONS
    Publication number: 20200054786
    Abstract: The present disclosure provides dermal fillers comprising hyaluronic acid-based hydrogels. The hydrogels are coacervates formed through ionic interactions between anionic polysaccharides, such as hyaluronic acid, and cationic polysaccharides, such as chitosan. The dermal fillers are useful for augmenting soft tissues, reducing soft tissue defects and improving skin quality.
    Type: Application
    Filed: October 13, 2016
    Publication date: February 20, 2020
    Inventors: Futian Liu, Xiaojie Yu, Dennis E. VanEpps, Iossif A. Strehin
  • Epimorphic Regeneration and Related Hydrogel Delivery Systems
    Publication number: 20190381031
    Abstract: Methods and compositions are described for enhancing tissue regeneration or wound repair in a mammalian subject comprising a composition comprising (a) a proline hydroxylase inhibitor component or molecule that increases or upregulates HIF1a and (b) a carrier component comprising a hydrogel.
    Type: Application
    Filed: June 3, 2019
    Publication date: December 19, 2019
    Inventors: Phillip B. Messersmith, Iossif A. Strehin, Ellen Heber-Katz
  • Epimorphic regeneration and related hydrogel delivery systems
    Patent number: 10307415
    Abstract: Methods and compositions are described for enhancing tissue regeneration or wound repair in a mammalian subject comprising a composition comprising (a) a proline hydroxylase inhibitor component or molecule that increases or upregulates HIF1a and (b) a carrier component comprising a hydrogel.
    Type: Grant
    Filed: June 9, 2017
    Date of Patent: June 4, 2019
    Assignees: Northwestern University, The Wistar Institute of Anatomy and Biology
    Inventors: Phillip B. Messersmith, Iossif A. Strehin, Ellen Heber-Katz
  • Epimorphic regeneration and related hydrogel delivery systems
    Patent number: 9675607
    Abstract: Methods and compositions are described for enhancing tissue regeneration or wound repair in a mammalian subject comprising a composition comprising (a) a proline hydroxylase inhibitor component or molecule that increases or upregulates HIF1a and (b) a carrier component comprising a hydrogel.
    Type: Grant
    Filed: November 13, 2014
    Date of Patent: June 13, 2017
    Assignees: Northwestern University, The Wistar Institute of Anatomy and Biology
    Inventors: Phillip B. Messersmith, Iossif A. Strehin, Ellen Heber-Katz
  • POLYMER HYDROGEL ADHESIVES FORMED WITH MULTIPLE CROSSLINKING MECHANISMS AT PHYSIOLOGIC PH
    Publication number: 20160243275
    Abstract: The present invention encompasses biocompatible reactants, biocompatible product hydrogels, methods of use thereof, and methods of synthesis thereof using a novel crosslinking mechanism between a first reactant compound including an N-Hydroxysuccinimide (NHS) ester group and a second reactant compound including a N-terminal cysteine amine group. In certain embodiments, one or more of the reactant compounds may be a macromonomer.
    Type: Application
    Filed: December 29, 2015
    Publication date: August 25, 2016
    Inventors: Phillip B. Messersmith, Devin G. Barrett, Iossif A. Strehin
  • IMIDATED BIOPOLYMER ADHESIVE AND HYDROGEL
    Publication number: 20160129149
    Abstract: Biologically compatible polymers carry an imide and can be used as an adhesive, a hydrogel or both. A second biologically compatible polymer reactive with the imidated polymer can be used therewith to seal openings.
    Type: Application
    Filed: January 5, 2016
    Publication date: May 12, 2016
    Inventors: Jennifer H. Elisseeff, Iossif A. Strehin, Xiaokun Wang
  • Imidated biopolymer adhesive and hydrogel
    Patent number: 9259505
    Abstract: Biologically compatible polymers carry an imide and can be used as an adhesive, a hydrogel or both. A second biologically compatible polymer reactive with the imidated polymer can be used therewith to seal openings.
    Type: Grant
    Filed: December 17, 2014
    Date of Patent: February 16, 2016
    Assignee: The Johns Hopkins University
    Inventors: Jennifer H. Elisseeff, Iossif A. Strehin
  • Polymer hydrogel adhesives formed with multiple crosslinking mechanisms at physiologic pH
    Patent number: 9259473
    Abstract: The present invention encompasses biocompatible reactants, biocompatible product hydrogels, methods of use thereof, and methods of synthesis thereof using a novel crosslinking mechanism between a first reactant compound including an N-Hydroxysuccinimide (NHS) ester group and a second reactant compound including a N-terminal cysteine amine group. In certain embodiments, one or more of the reactant compounds may be a macromonomer.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: February 16, 2016
    Assignee: Northwestern University
    Inventors: Phillip B. Messersmith, Devin G. Barrett, Iossif A. Strehin
  • Epimorphic Regeneration and Related Hidrogel Delivery Systems
    Publication number: 20150320877
    Abstract: Methods and compositions are described for enhancing tissue regeneration or wound repair in a mammalian subject comprising a composition comprising (a) a proline hydroxylase inhibitor component or molecule that increases or upregulates HIF1a and (b) a carrier component comprising a hydrogel.
    Type: Application
    Filed: November 13, 2014
    Publication date: November 12, 2015
    Inventors: Phillip B. Messersmith, Iossif A. Strehin, Ellen Heber-Katz
  • IMIDATED BIOPOLYMER ADHESIVE AND HYDROGEL
    Publication number: 20150297784
    Abstract: Biologically compatible polymers carry an imide and can be used as an adhesive, a hydrogel or both. A second biologically compatible polymer reactive with the imidated polymer can be used therewith to seal openings.
    Type: Application
    Filed: December 17, 2014
    Publication date: October 22, 2015
    Inventors: Jennifer H. Elisseeff, Iossif A. Strehin
  • Imidated biopolymer adhesive and hydrogel
    Patent number: 8946191
    Abstract: Biologically compatible polymers carry an imide and can be used as an adhesive, a hydrogel or both. A second biologically compatible polymer reactive with the imidated polymer can be used therewith to seal openings.
    Type: Grant
    Filed: December 4, 2007
    Date of Patent: February 3, 2015
    Assignee: The Johns Hopkins University
    Inventors: Jennifer H. Elisseeff, Iossif A. Strehin
  • POLYMER HYDROGEL ADHESIVES FORMED WITH MULTIPLE CROSSLINKING MECHANISMS AT PHYSIOLOGIC PH
    Publication number: 20130345319
    Abstract: The present invention encompasses biocompatible reactants, biocompatible product hydrogels, methods of use thereof, and methods of synthesis thereof using a novel crosslinking mechanism between a first reactant compound including an N-Hydroxysuccinimide (NHS) ester group and a second reactant compound including a N-terminal cysteine amine group. In certain embodiments, one or more of the reactant compounds may be a macromonomer.
    Type: Application
    Filed: March 13, 2013
    Publication date: December 26, 2013
    Inventors: Phillip B. Messersmith, Devin G. Barrett, Iossif A. Strehin
  • IMIDATED BIOPOLYMER ADHESIVE AND HYDROGEL
    Publication number: 20100137241
    Abstract: Biologically compatible polymers carry an imide and can be used as an adhesive, a hydrogel or both. A second biologically compatible polymer reactive with the imidated polymer can be used therewith to seal openings.
    Type: Application
    Filed: December 4, 2007
    Publication date: June 3, 2010
    Applicant: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Jennifer H. Elisseeff, Iossif A. Strehin