Patents by Inventor Iqbal Sayeed

Iqbal Sayeed has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROGESTERONE PHOSPHATE ANALOGS AND USES RELATED THERETO
    Publication number: 20230357309
    Abstract: This disclosure relates to progesterone phosphate derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation such as those resulting from traumatic brain injury or stroke.
    Type: Application
    Filed: June 20, 2023
    Publication date: November 9, 2023
    Inventors: DAVID BRIAN GUTHRIE, MARK ANDREW LOOKWOOD, MICHAEL G. NATCHUS, DENNIS C. LIOTTA, DONALD G. STEIN, IQBAL SAYEED
  • Progesterone phosphate analogs and uses related thereto
    Patent number: 11725025
    Abstract: This disclosure relates to progesterone phophate derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation such as those resulting from traumatic brain injury or stroke.
    Type: Grant
    Filed: June 28, 2021
    Date of Patent: August 15, 2023
    Assignee: Emory University
    Inventors: David Brian Guthrie, Mark Andrew Lockwood, Michael G. Natchus, Dennis C. Liotta, Donald G. Stein, Iqbal Sayeed
  • Blood biomarkers for severe traumatic brain injuries
    Patent number: 11609236
    Abstract: Disclosed herein is the use of plasma osteopontin (OPN) levels for diagnosing and predicting the severity and outcomes in traumatic brain injury (TBI), such as adult and pediatric TBI. The disclosed method can be used to diagnose TBI in any subject, such as pediatric, adult, and geriatric subjects. However, the method is particularly useful in pediatric subjects where current methods are insufficient. A particularly useful advantage of the disclosed methods is the ability to diagnose Abusive Head Trauma (AHT) in a pediatric subject.
    Type: Grant
    Filed: October 4, 2019
    Date of Patent: March 21, 2023
    Assignee: Children's Healthcare of Atlanta, Inc.
    Inventors: Andrew Reisner, Laura Blackwell, Iqbal Sayeed
  • PROGESTERONE ANALOGS AND USES RELATED THERETO
    Publication number: 20220235092
    Abstract: This disclosure relates to progesterone derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation resulting from traumatic brain injury or stroke.
    Type: Application
    Filed: February 4, 2022
    Publication date: July 28, 2022
    Applicant: EMORY UNIVERSITY
    Inventors: David B. Guthrie, Mark A. Lockwood, Dennis C. Liotta, Michael G. Natchus, Donald G. Stein, Iqbal Sayeed
  • Progesterone analogs and uses related thereto
    Patent number: 11274118
    Abstract: This disclosure relates to progesterone derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation resulting from traumatic brain injury or stroke.
    Type: Grant
    Filed: May 23, 2019
    Date of Patent: March 15, 2022
    Assignee: EMORY UNIVERSITY
    Inventors: David B Guthrie, Mark A Lockwood, Dennis C. Liotta, Michael G Natchus, Donald G. Stein, Iqbal Sayeed
  • PROGESTERONE PHOSPHATE ANALOGS AND USES RELATED THERETO
    Publication number: 20210395294
    Abstract: This disclosure relates to progesterone phophate derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation such as those resulting from traumatic brain injury or stroke.
    Type: Application
    Filed: June 28, 2021
    Publication date: December 23, 2021
    Inventors: David Brian Guthrie, Mark Andrew Lockwood, Michael G. Natchus, Dennis C. Liotta, Donald G. Stein, Iqbal Sayeed
  • Progesterone phosphate analogs and uses related thereto
    Patent number: 11053276
    Abstract: This disclosure relates to progesterone phophate derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation such as those resulting from traumatic brain injury or stroke.
    Type: Grant
    Filed: October 11, 2019
    Date of Patent: July 6, 2021
    Assignee: EMORY UNIVERSITY
    Inventors: David Brian Guthrie, Mark Andrew Lockwood, Michael G. Natchus, Dennis C. Liotta, Donald G. Stein, Iqbal Sayeed
  • PROGESTERONE PHOSPHATE ANALOGS AND USES RELATED THERETO
    Publication number: 20200255470
    Abstract: This disclosure relates to progesterone phophate derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation such as those resulting from traumatic brain injury or stroke.
    Type: Application
    Filed: October 11, 2019
    Publication date: August 13, 2020
    Inventors: David Brian Guthrie, Mark Andrew Lockwood, Michael G. Natchus, Dennis C. Liotta, Donald G. Stein, Iqbal Sayeed
  • Steroid analogues for neuroprotection
    Patent number: 10716795
    Abstract: Provided are steroid analogues functionalized with polar substituents at the C3 and/or C20 positions of the steroid ring system that exhibit improved water solubility. Also provided are pharmaceutical compositions comprising the steroid analogues and methods using the novel steroid analogues for the treatment and prevention of neurodegeneration in a patient following injury to the central nervous system.
    Type: Grant
    Filed: April 4, 2018
    Date of Patent: July 21, 2020
    Assignee: Emory University
    Inventors: Christopher MacNevin, Donald G. Stein, Dennis C. Liotta, Iqbal Sayeed, David B. Guthrie, Mark A. Lockwood, Michael G. Natchus
  • BLOOD BIOMARKERS FOR SEVERE TRAUMATIC BRAIN INJURIES
    Publication number: 20200110098
    Abstract: Disclosed herein is the use of plasma osteopontin (OPN) levels for diagnosing and predicting the severity and outcomes in traumatic brain injury (TBI), such as adult and pediatric TBI. The disclosed method can be used to diagnose TBI in any subject, such as pediatric, adult, and geriatric subjects. However, the method is particularly useful in pediatric subjects where current methods are insufficient. A particularly useful advantage of the disclosed methods is the ability to diagnose Abusive Head Trauma (AHT) in a pediatric subject.
    Type: Application
    Filed: October 4, 2019
    Publication date: April 9, 2020
    Inventors: Andrew Reisner, Laura Blackwell, Iqbal Sayeed
  • Progesterone phosphate analogs and uses related thereto
    Patent number: 10487109
    Abstract: This disclosure relates to progesterone phophate derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation such as those resulting from traumatic brain injury or stroke.
    Type: Grant
    Filed: October 9, 2017
    Date of Patent: November 26, 2019
    Assignee: Emory University
    Inventors: David Brian Guthrie, Mark Andrew Lockwood, Michael G. Natchus, Dennis C. Liotta, Donald G. Stein, Iqbal Sayeed
  • PROGESTERONE ANALOGS AND USES RELATED THERETO
    Publication number: 20190276489
    Abstract: This disclosure relates to progesterone derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation resulting from traumatic brain injury or stroke.
    Type: Application
    Filed: May 23, 2019
    Publication date: September 12, 2019
    Inventors: David B. Guthrie, Mark A. Lockwood, Dennis C. Liotta, Michael G. Natchus, Donald G. Stein, Iqbal Sayeed
  • Progesterone analogs and uses related thereto
    Patent number: 10336787
    Abstract: This disclosure relates to progesterone derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation resulting from traumatic brain injury or stroke.
    Type: Grant
    Filed: November 4, 2015
    Date of Patent: July 2, 2019
    Assignee: Emory University
    Inventors: David B Guthrie, Mark A Lockwood, Dennis C. Liotta, Michael G Natchus, Donald G. Stein, Iqbal Sayeed
  • Steroid Analogues for Neuroprotection
    Publication number: 20180221390
    Abstract: Provided are steroid analogues functionalized with polar substituents at the C3 and/or C20 positions of the steroid ring system that exhibit improved water solubility. Also provided are pharmaceutical compositions comprising the steroid analogues and methods using the novel steroid analogues for the treatment and prevention of neurodegeneration in a patient following injury to the central nervous system.
    Type: Application
    Filed: April 4, 2018
    Publication date: August 9, 2018
    Inventors: Christopher MacNevin, Donald G. Stein, Dennis C. Liotta, Iqbal Sayeed, David B. Guthrie, Mark A. Lockwood, Michael G. Natchus
  • Progesterone Phosphate Analogs and Uses Related Thereto
    Publication number: 20180094018
    Abstract: This disclosure relates to progesterone phophate derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation such as those resulting from traumatic brain injury or stroke.
    Type: Application
    Filed: October 9, 2017
    Publication date: April 5, 2018
    Inventors: David Brian Guthrie, Mark Andrew Lockwood, Michael G. Natchus, Dennis C. Liotta, Donald G. Stein, Iqbal Sayeed
  • Progesterone phosphate analogs and uses related thereto
    Patent number: 9802978
    Abstract: This disclosure relates to progesterone phophate derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation such as those resulting from traumatic brain injury or stroke.
    Type: Grant
    Filed: August 11, 2014
    Date of Patent: October 31, 2017
    Assignee: Emory University
    Inventors: David Brian Guthrie, Mark Andrew Lockwood, Michael G. Natchus, Dennis C. Liotta, Donald G. Stein, Iqbal Sayeed
  • Steroid Analogues for Neuroprotection
    Publication number: 20170065615
    Abstract: Provided are steroid analogues functionalized with polar substituents at the C3 and/or C20 positions of the steroid ring system that exhibit improved water solubility. Also provided are pharmaceutical compositions comprising the steroid analogues and methods using the novel steroid analogues for the treatment and prevention of neurodegeneration in a patient following injury to the central nervous system.
    Type: Application
    Filed: November 18, 2016
    Publication date: March 9, 2017
    Inventors: Christopher MacNevin, Donald G. Stein, Dennis C. Liotta, Iqbal Sayeed, David B. Guthrie, Mark A. Lockwood, Michael G. Natchus
  • Steroid analogues for neuroprotection
    Patent number: 9527881
    Abstract: Provided are steroid analogues functionalized with polar substituents at the C3 and/or C20 positions of the steroid ring system that exhibit improved water solubility. Also provided are pharmaceutical compositions comprising the steroid analogues and methods using the novel steroid analogues for the treatment and prevention of neurodegeneration in a patient following injury to the central nervous system.
    Type: Grant
    Filed: February 26, 2009
    Date of Patent: December 27, 2016
    Assignee: Emory University
    Inventors: Christopher Macnevin, Donald G. Stein, Dennis C. Liotta, Iqbal Sayeed, David B. Guthrie, Mark A. Lockwood, Michael G. Natchus
  • Progesterone Phosphate Analogs and Uses Related Thereto
    Publication number: 20160194351
    Abstract: This disclosure relates to progesterone phophate derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation such as those resulting from traumatic brain injury or stroke.
    Type: Application
    Filed: August 11, 2014
    Publication date: July 7, 2016
    Applicant: Emory University
    Inventors: David Brian Guthrie, Mark Andrew Lockwood, Michael G. Natchus, Dennis C. Liotta, Donald G. Stein, Iqbal Sayeed
  • PROGESTERONE ANALOGS AND USES RELATED THERETO
    Publication number: 20160052957
    Abstract: This disclosure relates to progesterone derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation resulting from traumatic brain injury or stroke.
    Type: Application
    Filed: November 4, 2015
    Publication date: February 25, 2016
    Inventors: David B Guthrie, Mark A Lockwood, Dennis C. Liotta, Michael G Natchus, Donald G. Stein, Iqbal Sayeed