Abstract: A method and system for facilitating direct trading by generating a transferable tranche are provided. A method includes receiving at least one electronic transaction request from a user; computing a risk score of the at least one electronic transaction; responsive to the at least one electronic transaction being allowed based on the risk score, placing the at least one electronic transaction into a transferable transactions queue; and generating a transferable tranche for allocation of the queued electronic transactions.

Abstract: A method and system for facilitating direct trading of electronic transactions are provided. The method includes receiving a request to approve an electronic transaction; determining if the received electronic transaction is approved based in part on a risk score set for the received electronic transactions; tranching the received electronic transaction in a transferable tranche, wherein the transferable tranche includes a plurality of plurality of approved electronic transactions issued by at least two different users; and providing the transferable tranche to a trading platform to perform at least one action on each of the approved electronic transactions.

Abstract: The present invention relates to methods for elevating high density lipoprotein (HDL) plasma levels, decreasing the absorption of dietary cholesterol in the intestine, decreasing the plasma level of low density lipoprotein (LDL), and increasing the conversion of cholesterol to bile acids, utilizing LXR? selective agonists, usually without elevating the plasma levels of triglycerides. Also provided are methods of using such agonists to treat metabolic diseases alone or in combination with other active agents. Further provided are methods for treating obesity and methods for treating the complications of obesity including type II diabetes, cardiovascular disease, hyperlipidemia, and hypertension, administering an LXR?-selective antagonist.