Patents by Inventor Iraj GHAZI

Iraj GHAZI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for the purification of adeno-associated virus
    Patent number: 12781197
    Abstract: Provided herein are methods and compositions for the separation of an adeno-associated virus (AAV) particle from a mixture of the AAV and at least one contaminant using anion exchange chromatography. These methods and compositions allow for improved purification of complete AAV particles from contaminants such as AAV particles that lack a complete genome (e.g., empty capsids) and AAV degradation products.
    Type: Grant
    Filed: October 28, 2022
    Date of Patent: November 3, 2026
    Assignee: Oxford Biomedica (US) LLC
    Inventors: Michael Mercaldi, Ashish Sharma, Thomas Thiers, Luke Mustich, Shanshan Zhou, Zaid Junaid, Iraj Ghazi, Achyuta Teella, Alex Meola
  • METHODS AND COMPOSITIONS FOR THE PURIFICATION OF ADENO-ASSOCIATED VIRUS
    Publication number: 20230183658
    Abstract: Provided herein are methods and compositions for the separation of an adeno-associated virus (AAV) particle from a mixture of the AAV and at least one contaminant using anion exchange chromatography. These methods and compositions allow for improved purification of complete AAV particles from contaminants such as AAV particles that lack a complete genome (e.g., empty capsids) and AAV degradation products.
    Type: Application
    Filed: October 28, 2022
    Publication date: June 15, 2023
    Inventors: Michael MERCALDI, Ashish SHARMA, Thomas THIERS, Luke MUSTICH, Shanshan ZHOU, Zaid JUNAID, Iraj GHAZI, Achyuta TEELLA, Alex MEOLA
  • METHODS AND COMPOSITIONS FOR THE PURIFICATION OF ADENO-ASSOCIATED VIRUS
    Publication number: 20230183659
    Abstract: Provided herein are methods and compositions for the separation of an adeno-associated virus (AAV) particle from a mixture of the AAV and at least one contaminant using anion exchange chromatography. These methods and compositions allow for improved purification of complete AAV particles from contaminants such as AAV particles that lack a complete genome (e.g., empty capsids) and AAV degradation products.
    Type: Application
    Filed: October 28, 2022
    Publication date: June 15, 2023
    Inventors: Michael MERCALDI, Ashish Sharma, Thomas Thiers, Luke Mustich, Shanshan Zhou, Zaid Junaid, Iraj Ghazi, Achyuta Teella, Alex Meola