Patents by Inventor Iraj Lalezari

Iraj Lalezari has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of synthesis and novel compounds for pharmaceutical uses
    Patent number: 5093367
    Abstract: The present invention is concerned with a process for the synthesis of substituted arylureidophenexymethyl propionic acids and an analogous benzamides series of compounds which have activity in the dissociation of oxygen from hemoglobin. In addition the process may be utilized to prepare compounds which are known.
    Type: Grant
    Filed: February 7, 1990
    Date of Patent: March 3, 1992
    Assignee: Montefiore Medical Center
    Inventors: Iraj Lalezari, Parviz Lalezari
  • Method of synthesis and novel compounds for pharmaceutical uses
    Patent number: 4921997
    Abstract: The present invention is concerned with a process for the synthesis of substituted arylureidophenexymethyl propionic acids and an analogous benzamides series of compounds which have activity in the dissociation of oxygen from hemoglobin. In addition, the process may be utilized to prepare compounds which are known.
    Type: Grant
    Filed: June 15, 1988
    Date of Patent: May 1, 1990
    Assignee: Montefiore Medical Center
    Inventors: Iraj Lalezari, Parviz Lalezari
  • Process for the synthesis of esters and amides of carboxylic acids
    Patent number: 4780542
    Abstract: The invention relates to the preparation of an ester or an amide from an anhydride with an alcohol or an amine, wherein the anhydride is first prepared by reacting an acid and an alkyl chloroformate in a 100% aqueous medium, that is, 100% water.
    Type: Grant
    Filed: September 26, 1983
    Date of Patent: October 25, 1988
    Assignee: Montefiore Medical Center
    Inventor: Iraj Lalezari
  • Anti-curare agents
    Patent number: 4734275
    Abstract: This invention relates to a method for antagonizing induced the neuromuscular blocking effects of certain therapeutic agents and pathological disorders in mammals, which comprises administering to said mammal an antagonizing-effective amount of a compound of the formula: ##STR1## wherein R.sub.1 and R.sub.2 are each hydrogen, alkyl, alkenyl, alkynyl, aryl, aralkyl, cycloalkyl, cycloalkyl-lower alkyl or hydroxyalkyl, or, when taken together, form a heterocyclic ring with the nitrogen to which they are attached, with the proviso that both are not hydrogen;R.sub.3 is hydrogen or alkyl; andR.sub.4 is hydrogen, alkyl, alkenyl, alkynyl, halogen or acyl; or a salt thereof with acids.
    Type: Grant
    Filed: April 22, 1986
    Date of Patent: March 29, 1988
    Assignee: Research Corporation
    Inventors: Iraj Lalezari, Francis F. Foldes
  • Mixed anhydrides and processes thereof
    Patent number: 4499020
    Abstract: Mixed anhydrides products are described. These mixed anhydrides are produced by reaction of a carboxylic acid-containing steroid with a material having the formula: ##STR1## wherein: X is a halogenZ is an oxygen or sulfurR is a hydrocarbonin an inert organic solvent containing a Lewis base. These mixed anhydrides may in turn be reacted with, for example, an alcohol ammonia or amine to produce the corresponding ester or amide steroid.
    Type: Grant
    Filed: February 22, 1983
    Date of Patent: February 12, 1985
    Assignee: Montefiore Hospital and Medical Center, Inc.
    Inventor: Iraj Lalezari
  • Nucleoside ester compositions
    Patent number: 4418059
    Abstract: A composition comprising a nucleosidic anti-tumor agent esterified with a carboxylic acid-containing steroid is described. These steroid ester derivatives of, for example, a deoxyuridine compound provide enhanced anti-tumor effects in chemotherapy as compared to the corresponding nucleosides alone.
    Type: Grant
    Filed: July 20, 1981
    Date of Patent: November 29, 1983
    Assignees: Montefiore Medical Center, The Albert Einstein College of Medicine at Yeshiva University
    Inventor: Iraj Lalezari
  • Process for the production of thebaine
    Patent number: 4114314
    Abstract: Tissue cultures of cells from seed heads of Papaver bracteatum Lindl, Population Arya II, are grown in artificial nutrient media to produce thebaine which is then extracted therefrom. An example of an artificial nutrient medium used for the tissue culture is revised tobacco medium supplemented with 1% agar and 1ppm 2,4-dichlorophenoxyacetic acid.
    Type: Grant
    Filed: February 22, 1977
    Date of Patent: September 19, 1978
    Assignee: The Ministry of Science & Higher Education
    Inventors: Ali Shafiee, Iraj Lalezari, Narges Yassa