Patents by Inventor Irena Crnkovic-Mertens

Irena Crnkovic-Mertens has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptides for inducing apoptosis in tumor cells
    Patent number: 7544768
    Abstract: The present invention relates to peptides which interact with IAPs. IAPs are highly expressed in tumor cells which fail to undergo apoptosis. By binding to IAPs, the peptides of the present invention release tumor cells from the apoptosis block and thus provide a new tool for effective cancer therapy.
    Type: Grant
    Filed: July 1, 2003
    Date of Patent: June 9, 2009
    Assignee: Deutsches Krebsforschungszentrum Stiflung des Offentlichen Rechts
    Inventors: Karin Hoppe-Seyler, Felix Hoppe-Seyler, Irena Crnkovic-Mertens, Christian Rausch
  • Livin-specific sirnas for the treatment of therapy-resistant tumors
    Publication number: 20060264394
    Abstract: Provided is the use of siRNAs which are specific for the inhibitor of apoptosis protein (IAP) livin to sensitize tumor cells for apoptosis by down-regulating livin expression.
    Type: Application
    Filed: April 15, 2004
    Publication date: November 23, 2006
    Inventors: Karin Butz, Irena Crnkovic-Mertens, Felix Hoppe-Seyler
  • Peptides for inducing apoptosis in tumor cells
    Publication number: 20050203288
    Abstract: The present invention relates to peptides which interact with IAPs. IAPs are highly expressed in tumor cells which fail to undergo apoptosis. By binding to IAPs, the peptides of the present invention release tumor cells from the apoptosis block and thus provide a new tool for effective cancer therapy.
    Type: Application
    Filed: July 1, 2003
    Publication date: September 15, 2005
    Inventors: Karin Butz, Felix Hoppe-Seyler, Irena Crnkovic-Mertens, Christian Rausch