Patents by Inventor Irene Agerkvist

Irene Agerkvist has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROTECTING COMPOSITIONS FOR RECOMBINANTLY PRODUCED FACTOR VIII
    Publication number: 20190358301
    Abstract: A histidine-free composition comprising: a high purity factor VIII (r-factor VIII); arginine and/or sucrose; a surface-active agent to prevent or at least inhibit surface adsorption of factor VIII; an amount of calcium chloride for specific stabilization of factor VIII.
    Type: Application
    Filed: December 20, 2018
    Publication date: November 28, 2019
    Applicant: OCTAPHARMA AG
    Inventors: Brita Rippner, Josefin Knutsson, Ulrika Nilsson, Elsa Ivarsson, Irène Agerkvist
  • STABILIZING AGENT FOR PHARMACEUTICAL PROTEINS
    Publication number: 20190030169
    Abstract: A method for stabilising a human blood protein or human blood plasma protein with a molecular weight of >10 KDa by adding melezitose to a solution comprising the human blood protein or human blood plasma protein with a molecular weight of >10 KDa.
    Type: Application
    Filed: September 27, 2018
    Publication date: January 31, 2019
    Applicant: OCTAPHARMA AG
    Inventors: Elsa Ivarsson, Josefin Knutsson, Brita Rippner, Ulrika Nilsson, Irène Agerkvist
  • Stabilizing agent for pharmaceutical proteins
    Patent number: 10098956
    Abstract: A method for stabilizing a human blood protein or human blood plasma protein with a molecular weight of >10 KDa by adding melezitose to a solution comprising the human blood protein or human blood plasma protein with a molecular weight of >10 KDa.
    Type: Grant
    Filed: May 17, 2016
    Date of Patent: October 16, 2018
    Assignee: OCTAPHARMA AG
    Inventors: Elsa Ivarsson, Josefin Knutsson, Brita Rippner, Ulrika Nilsson, Irène Agerkvist
  • Stabilizing agent for pharmaceutical proteins
    Patent number: 9943600
    Abstract: A method for stabilising a human blood protein or human blood plasma protein with a molecular weight of >10 KDa by adding melezitose to a solution comprising the human blood protein or human blood plasma protein with a molecular weight of >10 KDa.
    Type: Grant
    Filed: April 4, 2014
    Date of Patent: April 17, 2018
    Assignee: OCTAPHARMA AG
    Inventors: Elsa Ivarsson, Josefin Knutsson, Brita Rippner, Ulrika Nilsson, Irene Agerkvist
  • STABILIZING AGENT FOR PHARMACEUTICAL PROTEINS
    Publication number: 20160256555
    Abstract: A method for stabilising a human blood protein or human blood plasma protein with a molecular weight of >10 KDa by adding melezitose to a solution comprising the human blood protein or human blood plasma protein with a molecular weight of >10 KDa.
    Type: Application
    Filed: May 17, 2016
    Publication date: September 8, 2016
    Applicant: OCTAPHARMA AG
    Inventors: Elsa Ivarsson, Josefin Knutsson, Brita Rippner, Ulrika Nilsson, Irène Agerkvist
  • Method of increasing the productivity of eucaryotic cells in the production of recombinant FVIII
    Patent number: 9115381
    Abstract: A method of increasing productivity, in particularly cell-specific productivity, of recombinant factor VIII (rFVIII) produced in a eukaryotic cell suspension during culturing of the eucaryotic cell suspension in a culturing medium containing not more than 500 ?M CaCl2, at least a non-ionic detergent and other nutrient components needed for the cells to grow and produce rFVIII, the cell suspension is cultured under conditions inducing a shear stress mechanically to the eucaryotic cell suspension by adding a power density of at least 3 W/m3.
    Type: Grant
    Filed: May 14, 2012
    Date of Patent: August 25, 2015
    Assignee: Octapharma AG
    Inventors: Peter Aizawa, Irene Agerkvist
  • NEW PROTECTING COMPOSITIONS FOR RECOMBINANTLY PRODUCED FACTOR VII
    Publication number: 20150190478
    Abstract: A histidine-free composition comprising: a high purity factor VIII (r-factor VIII); arginine and/or sucrose; a surface-active agent to prevent or at least inhibit surface adsorption of factor VIII; an amount of calcium chloride for specific stabilization of factor VIII.
    Type: Application
    Filed: December 11, 2014
    Publication date: July 9, 2015
    Inventors: Brita RIPPNER, JOSEFIN ÖSTERBERG, ULRIKA NILSSON, ELSA IVARSSON, IRENE AGERKVIST
  • STABILIZING AGENT FOR PHARMACEUTICAL PROTEINS
    Publication number: 20140221290
    Abstract: A method for stabilising a human blood protein or human blood plasma protein with a molecular weight of >10 KDa by adding melezitose to a solution comprising the human blood protein or human blood plasma protein with a molecular weight of >10 KDa.
    Type: Application
    Filed: April 4, 2014
    Publication date: August 7, 2014
    Applicant: OCTAPHARMA AG
    Inventors: Elsa Ivarsson, Josefin Knutsson, Brita Rippner, Ulrika Nilsson, Irene Agerkvist
  • METHOD OF INCREASING THE PRODUCTIVITY OF EUCARYOTIC CELLS IN THE PRODUCTION OF RECOMBINANT FVIII
    Publication number: 20140051123
    Abstract: A method of increasing productivity, in particularly cell-specific productivity, of recombinant factor VIII (rFVIII) produced in a eukaryotic cell suspension during culturing of the eucaryotic cell suspension in a culturing medium containing not more than 500 ?M CaCl2, at least a non-ionic detergent and other nutrient components needed for the cells to grow and produce rFVIII, the cell suspension is cultured under conditions inducing a shear stress mechanically to the eucaryotic cell suspension by adding a power density of at least 3 W/m3.
    Type: Application
    Filed: May 14, 2012
    Publication date: February 20, 2014
    Applicant: OCTAPHARMA AG
    Inventors: Peter Aizawa, Irene Agerkvist
  • NEW STABILIZING AGENT FOR PHARMACEUTICAL PROTEINS
    Publication number: 20130116410
    Abstract: A method for stabilising a human blood protein or human blood plasma protein with a molecular weight of >10 KDa by adding melezitose to a solution comprising the human blood protein or human blood plasma protein with a molecular weight of >10 KDa.
    Type: Application
    Filed: April 20, 2011
    Publication date: May 9, 2013
    Applicant: OCTAPH ARMA AG
    Inventors: Elsa Ivarsson, Josefin Knutsson, Brita Rippner, Ulrika Nilsson, Irene Agerkvist
  • NEW PROTECTING COMPOSITIONS FOR RECOMBINANTLY PRODUCED FACTOR VIII
    Publication number: 20110178019
    Abstract: A histidine-free composition comprising: a high purity factor VIII (r-factor VIII); arginine and/or sucrose; a surface-active agent to prevent or at least inhibit surface adsorption of factor VIII; an amount of calcium chloride for specific stabilization of factor VIII.
    Type: Application
    Filed: September 3, 2009
    Publication date: July 21, 2011
    Inventors: Brita Rippner, Josefin Österberg, Ulrika Nilsson, Elsa Ivarsson, Irene Agerkvist