Patents by Inventor Irene Canton

Irene Canton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Media for stem cells
    Patent number: 10150946
    Abstract: The present invention relates to a medium for storing, preserving, culturing, and/or differentiating stem cells. The medium employs a synthetic thermo-responsive copolymer, dispersed in an aqueous vehicle, which allows the medium to be readily “switched” between a non-gelatinous (fluid) form and a gelatinous form by simply adjusting temperature across the gelling temperature of the medium. As such, stem cells can be easily captured within a 3D gel matrix by simply mixing the stem cells with the non-gelatinous/fluid form of the medium and then gelling the medium by adjusting the temperature across the gelling temperature of the medium. The stem cells encapsulated within the gelatinous form of the medium may then be preserved for a significant time period before either using the stem cells directly within the medium (e.g. in therapy, or in culturing, differentiation, and such like), or after their extraction from the medium.
    Type: Grant
    Filed: February 21, 2014
    Date of Patent: December 11, 2018
    Assignee: The University of Sheffield
    Inventors: Irene Canton, Steven Peter Armes, Nicholas John Warren, Harry Moore, Giuseppe Battaglia, Denis Cecchin
  • AMPHIPHILIC BLOCK COPOLYMERS FOR NUCLEIC ACID DELIVERY
    Publication number: 20160106673
    Abstract: The present invention provides a composition comprising vesicles and encapsulated within the vesicles, nucleic acid comprising less than 1000 nucleotides, wherein the vesicles comprise an amphiphilic block copolymer having a hydrophilic and a hydrophobic block. Methods of forming vesicles and methods of delivering nucleic acid, in particular, iRNA into cells, are also provided.
    Type: Application
    Filed: December 28, 2015
    Publication date: April 21, 2016
    Applicant: BIOCOMPATIBLES UK LIMITED
    Inventors: Andrew Lennard LEWIS, Giuseppe BATTAGLIA, Irene CANTON, Peter William STRATFORD
  • Amphiphilic block copolymers for nucleic acid delivery
    Patent number: 9254258
    Abstract: The present invention provides a composition comprising vesicles and encapsulated within the vesicles, nucleic acid comprising less than 1000 nucleotides, wherein the vesicles comprise an amphiphilic block copolymer having a hydrophilic and a hydrophobic block. Methods of forming vesicles and methods of delivering nucleic acid, in particular, iRNA into cells, are also provided.
    Type: Grant
    Filed: May 14, 2009
    Date of Patent: February 9, 2016
    Assignee: BIOCOMPATIBLES UK LIMITED
    Inventors: Andrew Lennard Lewis, Giuseppe Battaglia, Irene Canton, Peter William Stratford
  • MEDIA FOR STEM CELLS
    Publication number: 20150376567
    Abstract: The present invention relates to a medium for storing, preserving, culturing, and/or differentiating stem cells. The medium employs a synthetic thermo-responsive copolymer, dispersed in an aqueous vehicle, which allows the medium to be readily “switched” between a non-gelatinous (fluid) form and a gelatinous form by simply adjusting temperature across the gelling temperature of the medium. As such, stem cells can be easily captured within a 3D gel matrix by simply mixing the stem cells with the non-gelatinous/fluid form of the medium and then gelling the medium by adjusting the temperature across the gelling temperature of the medium. The stem cells encapsulated within the gelatinous form of the medium may then be preserved for a significant time period before either using the stem cells directly within the medium (e.g. in therapy, or in culturing, differentiation, and such like), or after their extraction from the medium.
    Type: Application
    Filed: February 21, 2014
    Publication date: December 31, 2015
    Applicant: The University of Sheffield
    Inventors: Irene Canton, Steven Peter Armes, Nicholas John Warren, Harry Moore, Guiseppe Battaglia, Denis Cecchin
  • AMPHIPHILIC BLOCK COPOLYMERS FOR NUCLEIC ACID DELIVERY
    Publication number: 20110151013
    Abstract: The present invention provides a composition comprising vesicles and encapsulated within the vesicles, nucleic acid comprising less than 1000 nucleotides, wherein the vesicles comprise an amphiphilic block copolymer having a hydrophilic and a hydrophobic block. Methods of forming vesicles and methods of delivering nucleic acid, in particular, iRNA into cells, are also provided.
    Type: Application
    Filed: May 14, 2009
    Publication date: June 23, 2011
    Applicant: BIOCOMPATIBLES UK LIMITED
    Inventors: Andrew Lennard Lewis, Giuseppe Battaglia, Irene Canton, Peter William Stratford