Patents by Inventor Irene Petrov
Irene Petrov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240130709Abstract: Apparatus and methods are described for ultrasound guided optoacoustic monitoring to provide diagnostic information for many clinical applications of blood oxygenation in blood vessels and in tissues including for early diagnosis and management of circulatory shock (including that induced by hemorrhage). In certain embodiments provided herein, methods and apparatus for optoacoustics for measurement of blood oxygenation in the innominate vein are provided. In certain embodiments provided herein, are methods and apparatus for articulating an angle between an ultrasound probe and subject body to identify an optimum position for an optoacoustic probe to measure blood oxygenation in a target blood vessel or tissue.Type: ApplicationFiled: December 13, 2023Publication date: April 25, 2024Inventors: DONALD S. PROUGH, III, YURIY PETROV, CHARLES HOUSSIERE, IRENE PETROV, TRIS MILLER
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Publication number: 20230233088Abstract: The systems, devices, and methods herein make optoacoustic measurements and correct or normalize them for variations in optical energy level of the different light pulses used. An optical source directs optical pulses to tissue, an optical energy meter measures the optical energy of the different optical pulses, an acoustic detector measures an acoustic response generated by the tissue in response to the optical pulses, and a processor calculates a concentration of an analyte based on the measured acoustic response and as corrected or normalized for the different energy levels among the optical pulses.Type: ApplicationFiled: March 21, 2023Publication date: July 27, 2023Inventors: Rinat ESENALIEV, Irene Petrov, Yuriy Petrov
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Patent number: 11638611Abstract: In one embodiment, a system for locating a tip of a catheter that has been inserted into a patient includes an implantable catheter having a distal tip, a pulsed light source that is co-located with the distal tip of the implantable catheter, the pulsed light source being configured to emit pulses of light into surrounding patient tissue, an optoacoustic sensor configured to be applied so a skin surface of the patient at a position proximate to the pulsed light source and to sense optoacoustic waves generated when the pulses of light are absorbed by the surrounding patient tissue, and an optoacoustic console configured to receive optoacoustic wave signals from the optoacoustic sensor and to display an indication of the optoacoustic wave signals to a medical professional to provide an indication of the location of the pulsed light source and, therefore, the distal tip of the implantable catheter.Type: GrantFiled: May 3, 2019Date of Patent: May 2, 2023Assignee: Board of Regents, The University of Texas SystemInventors: Rovnat Babazade, Yuriy Petrov, Irene Petrov, Rinat O. Esenaliev
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Patent number: 11045121Abstract: Optoacoustic diagnostic systems, devices, and methods are described. A system may comprise a console unit and a handheld probe. The console unit comprises a controller, a processor, a photodiode array, an acoustic processing subsystem, and a cooling subsystem. The probe directs light signals from the photodiode array to patient tissue. The light signals each have different wavelengths selected based on the physiological parameter of interest. The probe further comprises an acoustic transducer that receives acoustic signals generated in response to the directed light signals. The probe may comprise a finger-held working end that can be directed to the skull of a fetus within the uterus during labor. The probe can then accurately determine blood oxygenation of the fetus to determine if a caesarian section is necessary.Type: GrantFiled: January 22, 2019Date of Patent: June 29, 2021Assignee: Noninvasix, Inc.Inventors: Rinat Esenaliev, Donald S. Prough, Yuriy Petrov, Irene Petrov, George Saade, Gayle L. Olson, Tommy G. Cooper
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Publication number: 20200345985Abstract: In one embodiment, a system for locating a tip of a catheter that has been inserted into a patient includes an implantable catheter having a distal tip, a pulsed light source that is co-located with the distal tip of the implantable catheter, the pulsed light source being configured to emit pulses of light into surrounding patient tissue, an optoacoustic sensor configured to be applied so a skin surface of the patient at a position proximate to the pulsed light source and to sense optoacoustic waves generated when the pulses of light are absorbed by the surrounding patient tissue, and an optoacoustic console configured to receive optoacoustic wave signals from the optoacoustic sensor and to display an indication of the optoacoustic wave signals to a medical professional to provide an indication of the location of the pulsed light source and, therefore, the distal tip of the implantable catheter.Type: ApplicationFiled: May 3, 2019Publication date: November 5, 2020Applicant: Board of Regents, The University of Texas SystemInventors: Rovnat Babazade, Yuriy Petrov, Irene Petrov, Rinat O. Esenaliev
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Publication number: 20200337781Abstract: In one embodiment, a system for locating a tip of a catheter that has been inserted into a patient includes an implantable catheter having a distal tip, a pulsed light source that is co-located with the distal tip of the implantable catheter, the pulsed light source being configured to emit pulses of light into surrounding patient tissue, an optoacoustic sensor configured to be applied so a skin surface of the patient at a position proximate to the pulsed light source and to sense optoacoustic waves generated when the pulses of light are absorbed by the surrounding patient tissue, and an optoacoustic console configured to receive optoacoustic wave signals from the optoacoustic sensor and to display an indication of the optoacoustic wave signals to a medical professional to provide an indication of the location of the pulsed light source and, therefore, the distal tip of the implantable catheter.Type: ApplicationFiled: April 24, 2019Publication date: October 29, 2020Applicant: Board of Regents, The University of Texas SystemInventors: Rovnat Babazade, Yuriy Petrov, Irene Petrov, Rinat O. Esenaliev
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Publication number: 20190216376Abstract: Optoacoustic diagnostic systems, devices, and methods are described. A system may comprise a console unit and a handheld probe. The console unit comprises a controller, a processor, a photodiode array, an acoustic processing subsystem, and a cooling subsystem. The probe directs light signals from the photodiode array to patient tissue. The light signals each have different wavelengths selected based on the physiological parameter of interest. The probe further comprises an acoustic transducer that receives acoustic signals generated in response to the directed light signals. The probe may comprise a finger-held working end that can be directed to the skull of a fetus within the uterus during labor. The probe can then accurately determine blood oxygenation of the fetus to determine if a caesarian section is necessary.Type: ApplicationFiled: January 22, 2019Publication date: July 18, 2019Inventors: Rinat ESENALIEV, Donald S. PROUGH, Yuriy PETROV, Irene PETROV, George SAADE, Gayle L. OLSON, Tommy G. COOPER
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Patent number: 10307088Abstract: Optoacoustic diagnostic systems, devices, and methods are described. A system may comprise a console unit and a handheld probe. The console unit comprises a controller, a processor, a photodiode array, an acoustic processing subsystem, and a cooling subsystem. The probe directs light signals from the photodiode array to patient tissue. The light signals each have different wavelengths selected based on the physiological parameter of interest. The probe further comprises an acoustic transducer that receives acoustic signals generated in response to the directed light signals. The probe may comprise a finger-held working end that can be directed to the skull of a fetus within the uterus during labor. The probe can then accurately determine blood oxygenation of the fetus to determine if a caesarian section is necessary.Type: GrantFiled: July 8, 2015Date of Patent: June 4, 2019Assignee: The Board of Regents of the University of TexasInventors: Rinat Esenaliev, Donald S. Prough, Yuriy Petrov, Irene Petrov, George Saade, Gayle L. Olson
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Patent number: 10231656Abstract: Optoacoustic diagnostic systems, devices, and methods are described. A system may comprise a console unit and a handheld probe. The console unit comprises a controller, a processor, a photodiode array, an acoustic processing subsystem, and a cooling subsystem. The probe directs light signals from the photodiode array to patient tissue. The light signals each have different wavelengths selected based on the physiological parameter of interest. The probe further comprises an acoustic transducer that receives acoustic signals generated in response to the directed light signals. The probe may comprise a finger-held working end that can be directed to the skull of a fetus within the uterus during labor. The probe can then accurately determine blood oxygenation of the fetus to determine if a caesarian section is necessary.Type: GrantFiled: July 8, 2015Date of Patent: March 19, 2019Assignees: Noninvasix, Inc., The Board of Regents of The University of TexasInventors: Rinat Esenaliev, Donald S. Prough, Yuriy Petrov, Irene Petrov, George Saade, Gayle L. Olson, Tommy G. Cooper
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Patent number: 10206607Abstract: Medical apparatus are disclosed for optoacoustic monitoring of an indwelling unit of the apparatus, where the indwelling unit includes one or more optical components capable of directing pulsed light into an overlying tissue. The apparatus also include one or more acoustic components in contact with an exterior surface of the tissue to detect induced pressure waves producing an acoustic output analyzed with an optoacoustic unit to monitor and confirm proper placement of the indwelling unit. Methods for using the apparatus are also disclosed.Type: GrantFiled: April 30, 2012Date of Patent: February 19, 2019Assignee: The Board of Regents of the University of Texas SystemInventors: Donald S. Prough, Rinat O. Esenaliev, Yuriy Petrov, Irene Petrov
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Patent number: 9380967Abstract: Optoacoustic diagnostic systems, devices, and methods are described. A system may comprise a console unit and a handheld probe. The console unit comprises a controller, a processor, a photodiode array, an acoustic processing subsystem, and a cooling subsystem. The probe directs light signals from the photodiode array to patient tissue. The light signals each have different wavelengths selected based on the physiological parameter of interest. The probe further comprises an acoustic transducer that receives acoustic signals generated in response to the directed light signals. The probe may comprise a finger-held working end that can be directed to the skull of a fetus within the uterus during labor. The probe can then accurately determine blood oxygenation of the fetus to determine if a caesarian section is necessary.Type: GrantFiled: July 8, 2015Date of Patent: July 5, 2016Assignee: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEMInventors: Rinat Esenaliev, Donald S. Prough, Yuriy Petrov, Irene Petrov, George Saade, Gayle L. Olson
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Publication number: 20160015304Abstract: Optoacoustic diagnostic systems, devices, and methods are described. A system may comprise a console unit and a handheld probe. The console unit comprises a controller, a processor, a photodiode array, an acoustic processing subsystem, and a cooling subsystem. The probe directs light signals from the photodiode array to patient tissue. The light signals each have different wavelengths selected based on the physiological parameter of interest. The probe further comprises an acoustic transducer that receives acoustic signals generated in response to the directed light signals. The probe may comprise a finger-held working end that can be directed to the skull of a fetus within the uterus during labor. The probe can then accurately determine blood oxygenation of the fetus to determine if a caesarian section is necessary.Type: ApplicationFiled: July 8, 2015Publication date: January 21, 2016Inventors: Rinat ESENALIEV, Donald S. PROUGH, Yuriy PETROV, Irene PETROV, George SAADE, Gayle L. OLSON, Tommy G. COOPER
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Publication number: 20160007895Abstract: Optoacoustic diagnostic systems, devices, and methods are described. A system may comprise a console unit and a handheld probe. The console unit comprises a controller, a processor, a photodiode array, an acoustic processing subsystem, and a cooling subsystem. The probe directs light signals from the photodiode array to patient tissue. The light signals each have different wavelengths selected based on the physiological parameter of interest. The probe further comprises an acoustic transducer that receives acoustic signals generated in response to the directed light signals. The probe may comprise a finger-held working end that can be directed to the skull of a fetus within the uterus during labor. The probe can then accurately determine blood oxygenation of the fetus to determine if a caesarian section is necessary.Type: ApplicationFiled: July 8, 2015Publication date: January 14, 2016Inventors: Rinat ESENALIEV, Donald S. PROUGH, Yuriy PETROV, Irene PETROV, George SAADE, Gayle L. OLSON
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Publication number: 20160007892Abstract: Optoacoustic diagnostic systems, devices, and methods are described. A system may comprise a console unit and a handheld probe. The console unit comprises a controller, a processor, a photodiode array, an acoustic processing subsystem, and a cooling subsystem. The probe directs light signals from the photodiode array to patient tissue. The light signals each have different wavelengths selected based on the physiological parameter of interest. The probe further comprises an acoustic transducer that receives acoustic signals generated in response to the directed light signals. The probe may comprise a finger-held working end that can be directed to the skull of a fetus within the uterus during labor. The probe can then accurately determine blood oxygenation of the fetus to determine if a caesarian section is necessary.Type: ApplicationFiled: July 8, 2015Publication date: January 14, 2016Inventors: Rinat ESENALIEV, Donald S. PROUGH, Yuriy PETROV, Irene PETROV, George SAADE, Gayle L. OLSON
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Publication number: 20140058253Abstract: Medical apparatus are disclosed for optoacoustic monitoring of an indwelling unit of the apparatus, where the indwelling unit includes one or more optical components capable of directing pulsed light into an overlying tissue. The apparatus also include one or more acoustic components in contact with an exterior surface of the tissue to detect induced pressure waves producing an acoustic output analyzed with an optoacoustic unit to monitor and confirm proper placement of the indwelling unit. Methods for using the apparatus are also disclosed.Type: ApplicationFiled: April 30, 2012Publication date: February 27, 2014Applicant: BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEMInventors: Donald S. Prough, Rinat O. Esenaliev, Yuriy Petrov, Irene Petrov
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Publication number: 20120203101Abstract: Indwelling medical apparatus including one optoacoustic discernible member or a plurality of optoacoustic discernible members and methods for optoacoustic guidance and confirmation of placement of optoacoustically discernible indwelling medical apparatus.Type: ApplicationFiled: July 9, 2011Publication date: August 9, 2012Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMInventors: Donald S. Prough, Rinat O. Esenaliev, Daneshvari R. Solanki, Michael Kinsky, Yuriy Petrov, Irene Petrov