Abstract: A method includes determining the presence or concentration of an analyte in a sample. Determining the presence or concentration of an analyte in a sample includes receiving a first image containing an image of the sample, the first image obtained using an image sensor having two or more colour channels. Determining the presence or concentration of an analyte in a sample includes extracting first and second mono-colour arrays from the first image, the first and second mono-colour arrays corresponding to different colour channels of the image sensor, wherein each mono-colour array comprises one or more entries and each entry is determined by aggregating one or more pixels of the first image.

Abstract: A lateral flow device is disclosed. The device comprises a test layer comprising a test region between opposite first and second end regions of the test layer, a first permeable layer having a first contact area in contact with the first end region, and a second permeable layer having a second contact area in contact with the first end region. The device further comprises a first non-permeable layer between the first and second permeable layers and having a third contact area with the first end region. The first contact area and the second contact area are separated by the third contact area. The device further comprises a sample pad in fluid contact with the first and second permeable layers for delivery of a sample fluid to the first and second contact regions. The second contact area is further from the second end region than the first contact area is from the second end region.

Abstract: A sensor for detection of a biological analyte comprises: a bottom gate thin film transistor comprising a gate electrode (103); source and drain electrodes (107, 109); a dielectric layer (105) between the gate electrode and the source and drain electrodes; and a semiconductor layer (111) comprising an organic semiconducting material extending between the source and drain electrodes; a binding layer comprising an amphiphilic polymer comprising a binding group (115) adjacent to and in direct contact with the semiconductor layer; and a receptor (220) bound to the binding group.

Abstract: A method includes determining the presence or concentration of an analyte in a sample. Determining the presence or concentration of an analyte in a sample includes receiving a first image containing an image of the sample, the first image obtained using an image sensor having two or more colour channels. Determining the presence or concentration of an analyte in a sample includes extracting first and second mono-colour arrays from the first image, the first and second mono-colour arrays corresponding to different colour channels of the image sensor, wherein each mono-colour array comprises one or more entries and each entry is determined by aggregating one or more pixels of the first image.

Abstract: A device for performing Raman spectroscopy is disclosed. The device comprises a sensor device comprising a transparent substrate having first and second opposite faces. The sensor device comprises a light source, a first grating, a first reflective element, and a light detector carried by the first face of the substrate. The light source is arranged to emit light towards the second face of the substrate and the light detector is directed at the second face of the substrate. The first grating is interposed between the light source and the light detector. The first reflective element is interposed between the light source and the first grating. The sensor device comprises a second grating and a second reflective element carried by the second face of the substrate, the second grating arranged to receive light from the light source and the second reflective element arranged to receive light from the first grating.