Abstract: Provided herein are ionic liquids that can be used as antifungal agents alone or in combination with Amphotericin B. Also disclosed are methods of synthesis of the ionic liquids and inhibiting fungal growth and methods of treating fungal infections using the disclosed compounds. The disclosure provides antifungal agents that potentiate the antifungal activity of Amphotericin B, a commonly used antifungal drug that could be used alone or in combination. This combination will help control and combat the infections caused by drug resistant Candida. auris in immunocompromised patients.

Abstract: Provided herein are homoleptic metal coordination complexes that induce cellular apoptosis and cell cycle arrest in G0/G1 phase in fungus, such as Candida spp. Also disclosed are methods of inhibiting fungal growth and methods of treating fungal infections using the disclosed compounds. The disclosed compounds exhibit anti-Candida activity against fluconazole resistant and sensitive strains of C. albicans at low concentrations.

Abstract: The present invention relates to a peptide having a fungicidal activity, isolated from Lactobacillus plantarum YML007, and provides a fungicidal peptide comprising the amino acid sequence of SEQ ID NO: 1. In addition, the present invention provides a fungicidal composition or a composition for food preservation, containing the peptide as an active ingredient. The peptide of the present invention has a wide range of fungicidal activities, and thus can be applied, by using the same, to various fields such as a microbial preparation related to fungicidal activity, an agent for controlling pathogenic fungi, a preservative for food including feed, and the future development of medical supplies related to fungi.