Patents by Inventor Irina A. Afonina

Irina A. Afonina has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220338529
    Abstract: There is provided an aerosolizable formulation comprising: (i) one or more aerosol-forming agents selected from the group consisting of mono-propylene glycol, di-propylene glycol, 1,3-propanediol, and mixtures thereof; (ii) water; and (iii) menthol in an amount of at least about 3% by weight of the aerosolizable formulation, wherein the weight ratio of the one or more aerosol forming agents to water is at least about 2:1.
    Type: Application
    Filed: September 11, 2020
    Publication date: October 27, 2022
    Inventors: Klaus Mathie, Irina Afonina
  • Patent number: 10879474
    Abstract: The present invention relates to organic dielectric layers comprising a polycycloolefinic polymer with a pendent chromophoric group having an absorption maximum in the wavelength range from 230 to 290 nm, and to organic electronic devices comprising them.
    Type: Grant
    Filed: May 15, 2017
    Date of Patent: December 29, 2020
    Assignees: PROMERUS, LLC, MERCK PATENT GMBH
    Inventors: Irina Afonina, Tomas Backlund, Larry F Rhodes, Hugh A Burgoon
  • Patent number: 10693072
    Abstract: The present invention relates to organic electronic devices, and more specifically to organic field effect transistors, comprising a dielectric layer that comprises a polycycloolefinic polymer and a diazirine compound.
    Type: Grant
    Filed: January 25, 2019
    Date of Patent: June 23, 2020
    Assignees: PROMERUS, LLC, MERCK PATENT GMBH
    Inventors: Larry F Rhodes, Hugh Burgoon, Irina Afonina, Tomas Backlund, Aurelie Morley
  • Publication number: 20190157558
    Abstract: The present invention relates to organic electronic devices, and more specifically to organic field effect transistors, comprising a dielectric layer that comprises a polycycloolefinic polymer and a diazirine compound.
    Type: Application
    Filed: January 25, 2019
    Publication date: May 23, 2019
    Applicants: PROMERUS, LLC, MERCK PATENT GMBH
    Inventors: LARRY F RHODES, HUGH BURGOON, IRINA AFONINA, TOMAS BACKLUND, AURELIE MORLEY
  • Publication number: 20190148657
    Abstract: The present invention relates to organic dielectric layers comprising a polycycloolefinic polymer with a pendent chromophoric group having an absorption maximum in the wavelength range from 230 to 290 nm, and to organic electronic devices comprising them.
    Type: Application
    Filed: May 15, 2017
    Publication date: May 16, 2019
    Applicants: PROMERUS, LLC, MERCK PATENT GMBH
    Inventors: IRINA AFONINA, TOMAS BACKLUND, LARRY F RHODES, HUGH A BURGOON
  • Patent number: 10266903
    Abstract: Primers and probes specific to the genes encoding extended spectrum beta-lactamase that involves CTX-M groups 1 and 9 that cause extended beta-lactamase resistance in bacteria are described herein, with methods and kits for using these primers and probes to detect CTX-M groups 1 and 9 nucleic acids. In the methods described, nucleic acids present in a clinical or test sample obtained from a biological sample or tissue suspected of containing the CTX-M groups 1 and 9 gene are amplified and corresponding sequences for CTX-M groups 1 and 9 are detected. The amplified nucleic acid can be detected by a variety of state of the art methods, including fluorescence resonance energy transfer (FRET), radiolabels, enzyme labels, and the like.
    Type: Grant
    Filed: December 3, 2015
    Date of Patent: April 23, 2019
    Assignee: ELITECHGROUP, INC.
    Inventors: Irina A. Afonina, Yevgeniy S. Belousov
  • Patent number: 10256409
    Abstract: The present invention relates to organic electronic devices, and more specifically to organic field effect transistors, comprising a dielectric layer that comprises a polycycloolefinic polymer and a diazirine compound.
    Type: Grant
    Filed: March 22, 2017
    Date of Patent: April 9, 2019
    Assignees: PROMERUS, LLC, MERCK PATENT GMBH
    Inventors: Larry F Rhodes, Hugh Burgoon, Irina Afonina, Tomas Backlund, Aurelie Morley
  • Patent number: 9988670
    Abstract: Primers and probes specific to genes encoding carbapenem-resistant Enterobacteriaceae (CREs) that include KPC (Klebsiella pneumoniae carbapenemase), NDM-1 (New Delhi Metallo-beta-lactamase), VIM (Verona Integron-Mediated Metallo-?-lactamase), IMP-type carbapenemase and OXA 48 (oxacillinase), that cause resistance in Enterobacteriaceae bacteria, are described herein, with methods and kits for using these primers and probes to detect target nucleic acids. In the methods described, nucleic acids present in a clinical or test sample obtained from a biological sample or tissue suspected of containing the the NDM1, KPC, IMP, VIM and OXA genes are amplified and corresponding sequences for the NDM1, KPC, IMP, VIM and OXA genes are detected. The amplified nucleic acid can be detected by a variety of state of the art methods, including fluorescence resonance energy transfer (FRET), radiolabels, enzyme labels, and the like.
    Type: Grant
    Filed: December 10, 2015
    Date of Patent: June 5, 2018
    Assignee: ELITECHGROUP B.V.
    Inventors: Irina A. Afonina, Yevgeniy S. Belousov
  • Patent number: 9978944
    Abstract: The present invention relates to organic electronic devices, and more specifically to organic field effect transistors, comprising a dielectric layer that comprises a polycycloolefinic polymer with an olefinic side chain.
    Type: Grant
    Filed: February 13, 2015
    Date of Patent: May 22, 2018
    Assignees: PROMERUS, LLC, MERCK PATENT GMBH
    Inventors: Larry F Rhodes, Crystal D Cyrus, Hugh A Burgoon, Irina Afonina, Toby Cull
  • Patent number: 9932643
    Abstract: The present methods pertain to amplifying and/or detecting Staphylococcus aureus (“SA”) and methicillin-resistant Staphylococcus aureus (“MRSA”) nucleic acids based on a combined detection of ldh1 as a SA marker and mecA as a MRSA marker. In certain embodiments the methods also pertain to amplifying and/or detecting one or more SCCmec integration sites or bridge regions. Primers and probes are suitable to be used in the present methods to detect SA and MRSA simultaneously in a single reaction or in separate reactions. The amplified nucleic acid can be detected by a variety of state of the art methods, including fluorescence resonance energy transfer (“FRET”), radiolabels, enzyme labels, and the like.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: April 3, 2018
    Assignee: ELITECHGROUP B.V.
    Inventors: Irina A. Afonina, Yevgeniy S. Belousov, Walt Mahoney
  • Publication number: 20170279048
    Abstract: The present invention relates to organic electronic devices, and more specifically to organic field effect transistors, comprising a dielectric layer that comprises a polycycloolefinic polymer and a diazirine compound.
    Type: Application
    Filed: March 22, 2017
    Publication date: September 28, 2017
    Applicants: PROMERUS, LLC, MERCK PATENT GMBH
    Inventors: LARRY F RHODES, HUGH BURGOON, IRINA AFONINA, TOMAS BACKLUND, AURELIE MORLEY
  • Publication number: 20170183717
    Abstract: The present methods pertain to amplifying and/or detecting Staphylococcus aureus (“SA”) and methicillin-resistant Staphylococcus aureus (“MRSA”) nucleic acids based on a combined detection of ldh1 as a SA marker and mecA as a MRSA marker. In certain embodiments the methods also pertain to amplifying and/or detecting one or more SCCmec integration sites or bridge regions. Primers and probes are suitable to be used in the present methods to detect SA and MRSA simultaneously in a single reaction or in separate reactions. The amplified nucleic acid can be detected by a variety of state of the art methods, including fluorescence resonance energy transfer (“FRET”), radiolabels, enzyme labels, and the like.
    Type: Application
    Filed: March 9, 2017
    Publication date: June 29, 2017
    Inventors: Irina A. Afonina, Yevgeniy S. Belousov, Walt Mahoney
  • Patent number: 9691985
    Abstract: The invention generally relates to passivation layers for use in organic electronic devices, and more specifically in organic field effect transistors, to processes for preparing such passivation layers, and to organic electronic devices and organic field effect transistors encompassing such passivation layers.
    Type: Grant
    Filed: August 22, 2013
    Date of Patent: June 27, 2017
    Assignee: Merck Patent GmbH
    Inventors: Stephen Bain, Irina Afonina, Tomas Backlund, Paul Craig Brookes
  • Patent number: 9677142
    Abstract: The present methods pertain to amplifying and/or detecting Staphylococcus aureus (“SA”) and methicillin-resistant Staphylococcus aureus (“MRSA”) nucleic acids based on a combined detection of ldh1 as a SA marker and mecA as a MRSA marker. In certain embodiments the methods also pertain to amplifying and/or detecting one or more SCCmec integration sites or bridge regions. Primers and probes are suitable to be used in the present methods to detect SA and MRSA simultaneously in a single reaction or in separate reactions. The amplified nucleic acid can be detected by a variety of state of the art methods, including fluorescence resonance energy transfer (“FRET”), radiolabels, enzyme labels, and the like.
    Type: Grant
    Filed: May 24, 2012
    Date of Patent: June 13, 2017
    Assignee: ELITECHGROUP B.V.
    Inventors: Irina A. Afonina, Yevgeniy S. Belousov, Walt Mahoney
  • Publication number: 20170025612
    Abstract: The present invention relates to organic electronic devices, and more specifically to organic field effect transistors, comprising a dielectric layer that comprises a polycycloolefinic polymer with an olefinic side chain.
    Type: Application
    Filed: February 13, 2015
    Publication date: January 26, 2017
    Applicants: PROMERUS, LLC, MERCK PATENT GMBH
    Inventors: LARRY F RHODES, CRYSTAL D CYRUS, HUGH A BURGOON, IRINA AFONINA, TOBY CULL
  • Patent number: 9490439
    Abstract: The invention relates to organic electronic devices containing polycycloolefin planarization layers between the substrate and a functional layer such as a semiconducting layer, dielectric layer, or electrode; to the use of polycycloolefins as a planarization layer on the substrate of an organic electronic device; and to processes for preparing such polycycloolefin planarization layers and organic electronic devices.
    Type: Grant
    Filed: November 10, 2015
    Date of Patent: November 8, 2016
    Assignees: Merck Patent GmbH, Promerus, LLC
    Inventors: Piotr Wierzchowiec, Tomas Backlund, Li W. Tan, Irina Afonina, Pawel Miskiewicz, Paul C. Brookes, Larry F. Rhodes, Andrew Bell
  • Publication number: 20160168628
    Abstract: Primers and probes specific to the genes encoding extended spectrum beta-lactamase that involves CTX-M groups 1 and 9 that cause extended beta-lactamase resistance in bacteria are described herein, with methods and kits for using these primers and probes to detect CTX-M groups 1 and 9 nucleic acids. In the methods described, nucleic acids present in a clinical or test sample obtained from a biological sample or tissue suspected of containing the CTX-M groups 1 and 9 gene are amplified and corresponding sequences for CTX-M groups 1 and 9 are detected. The amplified nucleic acid can be detected by a variety of state of the art methods, including fluorescence resonance energy transfer (FRET), radiolabels, enzyme labels, and the like.
    Type: Application
    Filed: December 3, 2015
    Publication date: June 16, 2016
    Inventors: Irina A. Afonina, Yevgeniy S. Belousov
  • Publication number: 20160168625
    Abstract: Primers and probes specific to genes encoding carbapenem-resistant Enterobacteriaceae (CREs) that include KPC (Klebsiella pneumoniae carbapenemase), NDM-1 (New Delhi Metallo-beta-lactamase), VIM (Verona Integron-Mediated Metallo-?-lactamase), IMP-type carbapenemase and OXA 48 (oxacillinase), that cause resistance in Enterobacteriaceae bacteria, are described herein, with methods and kits for using these primers and probes to detect target nucleic acids. In the methods described, nucleic acids present in a clinical or test sample obtained from a biological sample or tissue suspected of containing the the NDM1, KPC, IMP, VIM and OXA genes are amplified and corresponding sequences for the NDM1, KPC, IMP, VIM and OXA genes are detected. The amplified nucleic acid can be detected by a variety of state of the art methods, including fluorescence resonance energy transfer (FRET), radiolabels, enzyme labels, and the like.
    Type: Application
    Filed: December 10, 2015
    Publication date: June 16, 2016
    Inventors: Irina A. Afonina, Yevgeniy S. Belousov
  • Publication number: 20160079551
    Abstract: The invention relates to organic electronic devices containing polycycloolefin planarization layers between the substrate and a functional layer such as a semiconducting layer, dielectric layer, or electrode; to the use of polycycloolefins as a planarization layer on the substrate of an organic electronic device; and to processes for preparing such polycycloolefin planarization layers and organic electronic devices.
    Type: Application
    Filed: November 10, 2015
    Publication date: March 17, 2016
    Inventors: Piotr Wierzchowiec, Tomas Backlund, Li W. Tan, Irina Afonina, Pawel Miskiewick, Paul C. Brookes, Larry F. Rhodes, Andrew Bell
  • Publication number: 20150275274
    Abstract: The present methods pertain to amplifying and/or detecting Staphylococcus aureus (“SA”) and methicillin-resistant Staphylococcus aureus (“MRSA”) nucleic acids based on a combined detection of ldh1 as a SA marker and mecA as a MRSA marker. In certain embodiments the methods also pertain to amplifying and/or detecting one or more SCCmec integration sites or bridge regions. Primers and probes are suitable to be used in the present methods to detect SA and MRSA simultaneously in a single reaction or in separate reactions. The amplified nucleic acid can be detected by a variety of state of the art methods, including fluorescence resonance energy transfer (“FRET”), radiolabels, enzyme labels, and the like.
    Type: Application
    Filed: May 24, 2012
    Publication date: October 1, 2015
    Inventors: Irina A. Afonina, Yevgeniy S. Belousov, Walt Mahoney