Patents by Inventor Irina Borisovna Altman

Irina Borisovna Altman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing an L-amino acid using a bacterium of the family Enterobacteriaceae having enhanced expression of the flagella formation and motility cascade genes
    Patent number: 9284584
    Abstract: The present invention provides a method for producing L-amino acid using a bacterium belonging to the family Enterobacteriaceae, particularly a motile bacterium belonging to the genus Escherichia, Enterobacter or Pantoea, wherein the bacterium has been modified so that expression of at least one gene of the flagella formation and motility cascade is enhanced.
    Type: Grant
    Filed: February 11, 2014
    Date of Patent: March 15, 2016
    Assignee: AJINOMOTO CO., INC.
    Inventors: Irina Borisovna Altman, Tatyana Abramovna Yampolskaya, Leonid Romanovich Ptitsyn
  • Method for Producing an L-Amino Acid Using a Bacterium of the Enterobacteriaceae Family
    Publication number: 20150203881
    Abstract: A method for producing an L-amino acid is described, for example L-threonine, L-lysine, L-histidine, L-phenylalanine, L-arginine, L-tryptophan, or L-glutamic acid, using a bacterium of the Enterobacteriaceae family, wherein the bacterium has been modified to enhance an activity of a wild-type alcohol dehydrogenase encoded by the adhE gene or a mutant alcohol dehydrogenase which is resistant to aerobic inactivation.
    Type: Application
    Filed: March 25, 2015
    Publication date: July 23, 2015
    Applicant: AJINOMOTO CO., INC.
    Inventors: Leonid Romanovich Ptitsyn, Irina Borisovna Altman, Veronika Aleksandrovna Kotliarova, Olga Nikolaevna Mokhova, Tatyana Abramovna Yampolskaya, Yury Ivanovich Kozlov, Masaru Terashita, Yoshihiro Usuda, Kazuhiko Matsui
  • Method for Producing an L-Amino Acid Using a Bacterium of the Family Enterobacteriaceae Having Enhanced Expression of the Flagella Formation and Motility Cascade Genes
    Publication number: 20140162325
    Abstract: The present invention provides a method for producing L-amino acid using a bacterium belonging to the family Enterobacteriaceae, particularly a motile bacterium belonging to the genus Escherichia, Enterobacter or Pantoea, wherein the bacterium has been modified so that expression of at least one gene of the flagella formation and motility cascade is enhanced.
    Type: Application
    Filed: February 11, 2014
    Publication date: June 12, 2014
    Applicant: AJINOMOTO CO., INC.
    Inventors: Irina Borisovna Altman, Tatyana Abramovna Yampolskaya, Leonid Romanovich Ptitsyn
  • Method for Producing an L-Amino Acid Using a Bacterium of the Enterobacteriaceae Family
    Publication number: 20140147909
    Abstract: The present invention provides a method for producing an L-amino acid from ethanol using a bacterium of the Enterobacteriaceae family, wherein the bacterium has been modified to enhance the expression of the ydbK gene.
    Type: Application
    Filed: February 6, 2014
    Publication date: May 29, 2014
    Applicant: AJINOMOTO CO., INC.
    Inventors: Tatyana Abramovna Yampolskaya, Natalia Viktorovna Stoynova, Natalia Sergeevna Eremina, Irina Borisovna Altman, Leonid Romanovich Ptitsyn
  • Method for producing an L-amino acid using a bacterium of the family
    Patent number: 8679798
    Abstract: The present invention provides a method for producing an L-amino acid from ethanol using a bacterium of the Enterobacteriaceae family, wherein the bacterium has been modified to enhance the expression of the ydbK gene.
    Type: Grant
    Filed: September 2, 2008
    Date of Patent: March 25, 2014
    Assignee: Ajinomoto Co., Inc.
    Inventors: Tatyana Abramovna Yampolskaya, Natalia Viktorovna Stoynova, Natalia Sergeevna Eremina, Irina Borisovna Altman, Leonid Romanovich Ptitsyn
  • METHOD FOR PRODUCING AN L-AMINO ACID USING A BACTERIUM OF THE ENTEROBACTERIACEAE FAMILY
    Publication number: 20090203090
    Abstract: A method for producing an L-amino acid is described, for example L-threonine, L-lysine, L-histidine, L-phenylalanine, L-arginine, L-tryptophan, or L-glutamic acid, using a bacterium of the Enterobacteriaceae family, wherein the bacterium has been modified to enhance an activity of a wild-type alcohol dehydrogenase encoded by the adhE gene or a mutant alcohol dehydrogenase which is resistant to aerobic inactivation.
    Type: Application
    Filed: January 15, 2009
    Publication date: August 13, 2009
    Inventors: LEONID ROMANOVICH PTITSYN, IRINA BORISOVNA ALTMAN, VERONIKA ALEKSANDROVNA KOTLIAROVA, OLGA NIKOLAEVNA MOKHOVA, TATYANA ABRAMOVNA YAMPOLSKAYA, Yury Ivanovich Kozlov, Vitaly Grigorievich Paraskevov, MASARU TERASHITA, YOSHIHIRO USUDA, KAZUHIKO MATSUI
  • METHOD FOR PRODUCING AN L-AMINO ACID USING A BACTERIUM OF THE ENTEROBACTERIACEAE FAMILY
    Publication number: 20090162908
    Abstract: The present invention provides a method for producing an L-amino acid from ethanol using a bacterium of the Enterobacteriaceae family, wherein the bacterium has been modified to enhance the expression of the ydbK gene.
    Type: Application
    Filed: September 2, 2008
    Publication date: June 25, 2009
    Inventors: Tatyana Abramovna Yampolskaya, Natalia Viktorovna Stoynova, Natalia Sergeevna Eremina, Irina Borisovna Altman, Leonid Romanovich Ptitsyn
  • Mutant carbamoylphosphate synthetase and method for producing compounds derived from carbamoylphosphate
    Patent number: 7211419
    Abstract: L-arginine, citrulline and pyrimidine derivatives including orotic acid, uridine, uridine 5?-monophosphate (UMP), cytidine and cytidine 5?-monophosphate (CMP) are produced using a bacterium belonging to the genus Escherichia harboring a mutant carbamoylphosphate synthetase in which the amino acid sequence corresponding to positions from 947 to 951 in a wild type carbamoylphosphate synthetase is replaced with any one of amino acid sequences of SEQ ID NOS: 1 to 9, and feedback inhibition by uridine 5?-monophosphate in the bacterium is desensitized.
    Type: Grant
    Filed: October 20, 2005
    Date of Patent: May 1, 2007
    Assignee: Ajinomoto Co., Inc.
    Inventors: Leonid Romanovich Ptitsyn, Sergey Vasil'evich Smirnov, Irina Borisovna Altman, Anna Eugenievna Novikova, Veronika Aleksandrovna Kotliarova, Mikhail Markovich Gusyatiner, Yulia Georgievna Rostova, Tatyana Abramovna Yampolskaya
  • Mutant -acetylglutamate synthase and method for L-arginine production
    Patent number: 7169586
    Abstract: L-arginine is produced using a bacterium belonging to the genus Escherichia harboring a mutant N-acetylglutamate synthase in which the amino acid sequence corresponding to positions from 15 to 19 in a wild type N-acetylglutamate synthase is replaced with any one of amino acid sequences of SEQ ID NOS: 1 to 4, and feedback inhibition by L-arginine is desensitized.
    Type: Grant
    Filed: July 15, 2004
    Date of Patent: January 30, 2007
    Assignee: Ajinomoto Co., Inc.
    Inventors: Leonid Romanovich Ptitsyn, Irina Borisovna Altman, Sergey Vasil'evich Smirnov, Yulia Georgievna Rostova, Tatyana Abramovna Yampolskaya, Tatyana Viktorovna Leonova, Mikhail Markovich Gusyatiner
  • Mutant carbamoylphosphate synthetase and method for producing compounds derived from carbamoylphosphate
    Patent number: 6991924
    Abstract: L-arginine, citrulline and pyrimidine derivatives including orotic acid, uridine, uridine 5?-monophosphate (UMP), cytidine and cytidine 5?-monophosphate (CMP) are produced using a bacterium belonging to the genus Escherichia harboring a mutant carbamoylphosphate synthetase in which the amino acid sequence corresponding to positions from 947 to 951 in a wild type carbamoylphosphate synthetase is replaced with any one of amino acid sequences of SEQ ID NOS: 1 to 9, and feedback inhibition by uridine 5?-monophosphate in the bacterium is desensitized.
    Type: Grant
    Filed: August 2, 2002
    Date of Patent: January 31, 2006
    Assignee: Ajinomoto Co., Inc.
    Inventors: Leonid Romanovich Ptitsyn, Sergey Vasil'evich Smirnov, Irina Borisovna Altman, Anna Eugenievna Novikova, Veronika Aleksandrovna Kotliarova, Mikhail Markovich Gusyatiner, Yulia Georgievna Rostova, Tatyana Abramovna Yampolskaya
  • Mutant N-acetylglutamate synthase and method for L-arginine production
    Patent number: 6790647
    Abstract: L-arginine is produced using a bacterium belonging to the genus Escherichia harboring a mutant N-acetylglutamate synthase in which the amino acid sequence corresponding to positions from 15 to 19 in a wild type N-acetylglutamate synthase is replaced with any one of amino acid sequences of SEQ ID NOS: 1 to 4, and feedback inhibition by L-arginine is desensitized.
    Type: Grant
    Filed: June 22, 2001
    Date of Patent: September 14, 2004
    Assignee: Ajinomoto Co., Inc.
    Inventors: Leonid Romanovich Ptitsyn, Irina Borisovna Altman, Sergey Vasil'evich Smirnov, Yulia Georgievna Rostova, Tatyana Abramovna Yampolskaya, Tatyana Viktorovna Leonova, Mikhail Markovich Gusyatiner
  • Mutant N-acetylglutamate synthase and method for L-arginine production
    Publication number: 20030148475
    Abstract: L-arginine is produced using a bacterium belonging to the genus Escherichia harboring a mutant N-acetylglutamate synthase in which the amino acid sequence corresponding to positions from 15 to 19 in a wild type N-acetylglutamate synthase is replaced with any one of amino acid sequences of SEQ ID NOS: 1 to 4, and feedback inhibition by L-arginine is desensitized.
    Type: Application
    Filed: June 22, 2001
    Publication date: August 7, 2003
    Applicant: AJINOMOTO CO., INC.
    Inventors: Leonid Romanovich Ptitsyn, Irina Borisovna Altman, Sergey Vasil?apos;evich Smirnov, Yulia Georgievna Rostova, Tatyana Abramovna Yampolskaya, Tatyana Viktorovna Leonova, Mikhail Markovich Gusyatiner
  • Mutant carbamoylphosphate synthetase and method for producing compounds derived from carbamoylphosphate
    Publication number: 20030129708
    Abstract: L-arginine, citrulline and pyrimidine derivatives including orotic acid, uridine, uridine 5′-monophosphate (UMP), cytidine and cytidine 5′-monophosphate (CMP) are produced using a bacterium belonging to the genus Escherichia harboring a mutant carbamoylphosphate synthetase in which the amino acid sequence corresponding to positions from 947 to 951 in a wild type carbamoylphosphate synthetase is replaced with any one of amino acid sequences of SEQ ID NOS: 1 to 9, and feedback inhibition by uridine 5′-monophosphate in the bacterium is desensitized.
    Type: Application
    Filed: November 12, 2002
    Publication date: July 10, 2003
    Applicant: AJINOMOTO CO., INC
    Inventors: Leonid Romanovich Ptitsyn, Sergey Vasil?apos;evich Smirnov, Irina Borisovna Altman, Anna Eugenievna Novikova, Veronika Aleksandrovna Kotliarova, Mikhail Markovich Gusyatiner, Yulia Georgievna Rostova, Tatyana Abramovna Yampolskaya