Patents by Inventor Irina Mazo

Irina Mazo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for the treatment of multiple myeloma
    Patent number: 8569280
    Abstract: Methods for treating multiple myeloma with inhibitors of CXCR4, such as AMD3100 and anti-CXCR4 antibodies, are described. The decreased expression of CXCR4 on multiple myeloma cells according to the invention results in decreased homing of the cells to the bone marrow and a reduction in the development of the disease. Also disclosed are pharmaceutical compositions incorporating such inhibitors for use in the therapeutic treatment of multiple myeloma. The treatment methods described herein can be used independently, or in conjunction with, other therapies for the treatment of multiple myeloma.
    Type: Grant
    Filed: September 22, 2010
    Date of Patent: October 29, 2013
    Assignee: Immune Disease Institute
    Inventors: Ulrich H. von Andrian, Irina Mazo, Jean-Marc Gauguet
  • METHODS FOR THE TREATMENT OF MULTIPLE MYELOMA
    Publication number: 20110070244
    Abstract: Methods for treating multiple myeloma with inhibitors of CXCR4, such as AMD3100 and anti-CXCR4 antibodies, are described. The decreased expression of CXCR4 on multiple myeloma cells according to the invention results in decreased homing of the cells to the bone marrow and a reduction in the development of the disease. Also disclosed are pharmaceutical compositions incorporating such inhibitors for use in the therapeutic treatment of multiple myeloma. The treatment methods described herein can be used independently, or in conjunction with, other therapies for the treatment of multiple myeloma.
    Type: Application
    Filed: September 22, 2010
    Publication date: March 24, 2011
    Applicant: THE CBR INSTITUTE FOR BIOMEDICAL RESEARCH, INC.
    Inventors: Ulrich H. von Andrian, Irina Mazo, Jean-Marc Gauguet
  • Methods for the treatment of multiple myeloma
    Patent number: 7825088
    Abstract: Methods for treating multiple myeloma with inhibitors of CXCR4 are described. The decreased expression of CXCR4 on multiple myeloma cells according to the invention results in decreased homing of the cells to the bone marrow and a reduction in the development of the disease. Also disclosed are pharmaceutical compositions incorporating such inhibitors for use in the therapeutic treatment of multiple myeloma. The treatment methods described herein can be used independently, or in conjunction with, other therapies for the treatment of multiple myeloma.
    Type: Grant
    Filed: April 24, 2006
    Date of Patent: November 2, 2010
    Assignee: The CBR Institute for Biomedical Research, Inc.
    Inventors: Ulrich H. von Andrian, Irina Mazo, Jean-Marc Gauguet
  • Methods for the treatment of multiple myeloma
    Publication number: 20070003558
    Abstract: Methods for treating multiple myeloma with inhibitors of CXCR4 are described. The decreased expression of CXCR4 on multiple myeloma cells according to the invention results in decreased homing of the cells to the bone marrow and a reduction in the development of the disease. Also disclosed are pharmaceutical compositions incorporating such inhibitors for use in the therapeutic treatment of multiple myeloma. The treatment methods described herein can be used independently, or in conjunction with, other therapies for the treatment of multiple myeloma.
    Type: Application
    Filed: April 24, 2006
    Publication date: January 4, 2007
    Inventors: Ulrich von Andrian, Irina Mazo, Jean-Marc Gauguet