Patents by Inventor Irina Sokolova

Irina Sokolova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD AND PROBES FOR THE DETECTION OF CANCER
    Publication number: 20120141987
    Abstract: Probe sets and methods of using probes and probe sets for the detection of cancer are described. Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if cancer cells are present the sample. Also included are methods of selecting a combination of probes for the detection of cancer.
    Type: Application
    Filed: July 14, 2011
    Publication date: June 7, 2012
    Inventors: Larry E. Morrison, Irina A. Sokolova, Steven A. Seelig, Kevin C. Halling
  • Detection of high grade dysplasia in cervical cells
    Patent number: 8043805
    Abstract: Methods of using probes and probe sets for the detection of high grade dysplasia and carcinoma in cervical cells are described. Methods of the invention include hybridizing one or more chromosomal probes to a biological sample obtained from a subject and detecting the hybridization pattern of the chromosomal probes to the sample to determine whether the subject has high grade dysplasia or carcinoma. Methods of the invention also include preliminary screening the cells for a marker associated with a risk for cancer, and preferably involves screening for HPV infected cells by in situ hybridization using an HPV probe mixture.
    Type: Grant
    Filed: April 13, 2009
    Date of Patent: October 25, 2011
    Assignee: Vysis, Inc.
    Inventors: Irina A. Sokolova, Steven A. Seelig, Larry E. Morrison, Walter King, Alicia Algeciras-Schimnich
  • Methods for the detection of lung cancer
    Patent number: 7998678
    Abstract: Probe sets and methods of using probes and probe sets for the detection of cancer are described. Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if cancer cells are present the sample. Also included are methods of selecting a combination of probes for the detection of cancer.
    Type: Grant
    Filed: August 6, 2009
    Date of Patent: August 16, 2011
    Assignees: VYSIS, Inc., Mayo Foundation for Medical Education and Research
    Inventors: Larry E. Morrison, Irina A. Sokolova, Steven A. Seelig, Kevin C. Halling
  • Method and probe set for detecting cancer
    Patent number: 7998670
    Abstract: Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.
    Type: Grant
    Filed: May 21, 2007
    Date of Patent: August 16, 2011
    Assignees: Mayo Foundation for Medical Education and Research, Vysis, Inc.
    Inventors: Kevin C. Halling, Robert B. Jenkins, Walter King, Irina A. Sokolova, Steven A. Seelig
  • METHOD AND PROBE SET FOR DETECTING CANCER
    Publication number: 20110177510
    Abstract: Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.
    Type: Application
    Filed: March 31, 2011
    Publication date: July 21, 2011
    Inventors: Kevin C. Halling, Robert B. Jenkins, Walter King, Irina A. Sokolova, Steven A. Seelig
  • METHODS AND PROBES FOR THE DETECTION OF CANCER
    Publication number: 20090298087
    Abstract: Probe sets and methods of using probes and probe sets for the detection of cancer are described. Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if cancer cells are present the sample. Also included are methods of selecting a combination of probes for the detection of cancer.
    Type: Application
    Filed: August 6, 2009
    Publication date: December 3, 2009
    Inventors: Larry E. Morrison, Irina A. Sokolova, Steven A. Seelig, Kevin C. Halling
  • DETECTION OF HIGH GRADE DYSPLASIA IN CERVICAL CELLS
    Publication number: 20090269768
    Abstract: Methods of using probes and probe sets for the detection of high grade dysplasia and carcinoma in cervical cells are described. Methods of the invention include hybridizing one or more chromosomal probes to a biological sample obtained from a subject and detecting the hybridization pattern of the chromosomal probes to the sample to determine whether the subject has high grade dysplasia or carcinoma. Methods of the invention also include preliminary screening the cells for a marker associated with a risk for cancer, and preferably involves screening for HPV infected cells by in situ hybridization using an HPV probe mixture.
    Type: Application
    Filed: April 13, 2009
    Publication date: October 29, 2009
    Applicant: Vysis, Inc.
    Inventors: IRINA A. SOKOLOVA, STEVEN A. SEELIG, LARRY E. MORRISON, WALTER KING, ALICIA ALGECIRAS-SCHIMNICH
  • Detection of high grade dysplasia in cervical cells
    Patent number: 7517645
    Abstract: Methods of using probes and probe sets for the detection of high grade dysplasia and carcinoma in cervical cells are described. Methods of the invention include hybridizing one or more chromosomal probes to a biological sample obtained from a subject and detecting the hybridization pattern of the chromosomal probes to the sample to determine whether the subject has high grade dysplasia or carcinoma. Methods of the invention also include preliminary screening the cells for a marker associated with a risk for cancer, and preferably involves screening for HPV infected cells by in situ hybridization using an HPV probe mixture.
    Type: Grant
    Filed: June 2, 2004
    Date of Patent: April 14, 2009
    Assignee: VYSIS, Inc.
    Inventors: Irina A. Sokolova, Steven A. Seelig, Larry E. Morrison, Walter King, Alicia Algeciras-Schimnich
  • Method and Probe Set for Detecting Cancer
    Publication number: 20080032302
    Abstract: Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.
    Type: Application
    Filed: May 21, 2007
    Publication date: February 7, 2008
    Applicants: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH, VYSIS, INC.
    Inventors: Kevin Halling, Robert Jenkins, Walter King, Irina Sokolova, Steven Seelig
  • Method and probe set for detecting cancer
    Patent number: 7232655
    Abstract: Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.
    Type: Grant
    Filed: April 12, 2002
    Date of Patent: June 19, 2007
    Assignees: Mayo Foundation for Medical Education and Research, Vysis, Inc.
    Inventors: Kevin C. Halling, Robert B. Jenkins, Walter King, Irina A. Sokolova, Steven A. Seelig
  • Methods and probes for the detection of cancer
    Publication number: 20060063194
    Abstract: Probe sets and methods of using probes and probe sets for the detection of cancer are described. Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if cancer cells are present the sample. Also included are methods of selecting a combination of probes for the detection of cancer.
    Type: Application
    Filed: October 27, 2005
    Publication date: March 23, 2006
    Applicant: Abbott Molecular Inc.
    Inventors: Larry Morrison, Irina Sokolova, Steven Seelig, Kevin Halling
  • Method for producing humic acid salts
    Publication number: 20050069974
    Abstract: Humic acid salts are produced, with a high output of useful products, by a liquid-phase oxidation of the mixture of an alkaline agent with a lignin-containing plant raw material having the total content of dry substances of 12-20%, said oxidation being carried out in two stages. In a first stage, pre-oxidation is carried out at a temperature of 50-190 DEG C. and a pressure of 0.5-3 MPa associated with simultaneous treatment with an oxygen-containing gas until a pH of 10.5-12 is reached. The second stage, i.e. oxidation is carried out in the similar conditions at a temperature of 170-200 DEG C. until a pH of 8.5-10 is reached. The by-product of cellulose production by a sulphite process, i.e. concentrated solutions of lignosulphonate or lignin is used as a lignin-containing plant raw material, said lignin being a by-product of hydrolysis production being continuously oxidised by air oxygen in two stages.
    Type: Application
    Filed: December 16, 2002
    Publication date: March 31, 2005
    Inventors: Oleg Gladkov, Rodion Poloskin, Yuri Polyakov, Irina Sokolova, Nicolay Sorokin, Aleksey Glebov
  • Detection of high grade dysplasia in cervical cells
    Publication number: 20050026190
    Abstract: Methods of using probes and probe sets for the detection of high grade dysplasia and carcinoma in cervical cells are described. Methods of the invention include hybridizing one or more chromosomal probes to a biological sample obtained from a subject and detecting the hybridization pattern of the chromosomal probes to the sample to determine whether the subject has high grade dysplasia or carcinoma. Methods of the invention also include preliminary screening the cells for a marker associated with a risk for cancer, and preferably involves screening for HPV infected cells by in situ hybridization using an HPV probe mixture.
    Type: Application
    Filed: June 2, 2004
    Publication date: February 3, 2005
    Inventors: Irina Sokolova, Steven Seelig, Larry Morrison, Walter King, Alicia Algeciras-Schimnich
  • Detection of high grade dysplasia in cervical cells
    Publication number: 20040248107
    Abstract: Methods of using probes and probe sets for the detection of high grade dysplasia and carcinoma in cervical cells are described. Methods of the invention include hybridizing one or more chromosomal probes to a biological sample obtained from a subject and detecting the hybridization pattern of the chromosomal probes to the sample to determine whether the subject has high grade dysplasia or carcinoma. Methods of the invention also include preliminary screening the cells for a marker associated with a risk for cancer.
    Type: Application
    Filed: June 9, 2003
    Publication date: December 9, 2004
    Inventors: Irina A. Sokolova, Walter King, Larry E. Morrison, Steven A. Seelig
  • Methods and probes for the detection of cancer
    Publication number: 20030087248
    Abstract: Probe sets and methods of using probes and probe sets for the detection of cancer are described. Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if cancer cells are present the sample. Also included are methods of selecting a combination of probes for the detection of cancer.
    Type: Application
    Filed: February 20, 2002
    Publication date: May 8, 2003
    Inventors: Larry E. Morrison, Irina A. Sokolova, Steven A. Seelig, Kevin C. Halling
  • Method and probe set for detecting cancer
    Publication number: 20020160409
    Abstract: Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.
    Type: Application
    Filed: April 12, 2002
    Publication date: October 31, 2002
    Inventors: Kevin C. Halling, Robert B. Jenkins, Walter King, Irina A. Sokolova, Steven A. Seelig
  • Method and probe set for detecting cancer
    Patent number: 6376188
    Abstract: Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.
    Type: Grant
    Filed: July 21, 2000
    Date of Patent: April 23, 2002
    Assignees: Mayo Foundation for Medical Education and Research, Vysis, Inc.
    Inventors: Kevin C. Halling, Robert B. Jenkins, Walter King, Irina A. Sokolova, Steven A. Seelig
  • Method and probe set for detecting cancer
    Patent number: 6174681
    Abstract: Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.
    Type: Grant
    Filed: March 5, 1999
    Date of Patent: January 16, 2001
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Kevin C. Halling, Robert B. Jenkins, Walter King, Irina A. Sokolova, Steven A. Seelig