Patents by Inventor Irina Vladimirovna Biryukova

Irina Vladimirovna Biryukova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of Producing L-Amino Acids
    Publication number: 20220010343
    Abstract: A method is described for producing an L-amino acid including the steps of cultivating in a culture medium an L-amino acid-producing bacterium belonging to the family Enterobacteriaceae to produce and accumulate the L-amino acid in the culture medium, cells of the bacterium, or both, and collecting the L-amino acid from the culture medium, the cells, or both, wherein said bacterium has been modified to overexpress a gene encoding a periplasmic adaptor protein.
    Type: Application
    Filed: September 27, 2021
    Publication date: January 13, 2022
    Applicant: AJINOMOTO CO., INC.
    Inventors: Natalia Viktorovna Stoynova, Olga Nikolaevna Igonina, Evgeniya Aleksandrovna Malykh, Natalya Sergeevna Plekhanova, Irena Alexandrovna Kononova, Ivan Alexandrovich Butov, Viktor Vasilievich Samsonov, Irina Vladimirovna Biryukova, Irina Segreevna Shmagina
  • Method for constructing an operon containing translationally coupled genes
    Patent number: 8394610
    Abstract: The present invention provides a method for constructing recombinant translationally coupled operons, a method for producing useful metabolites using the bacterium containing the coupled operons, and a method for monitoring gene expression.
    Type: Grant
    Filed: February 19, 2009
    Date of Patent: March 12, 2013
    Assignee: Ajinomoto Co., Inc.
    Inventors: Andrey Yurievich Gulevich, Aleksandra Yurievna Skorokhodova, Vladimir Yurievich Ermishev, Natalya Igorevna Minaeva, Danila Vadimovich Zimenkov, Aleksandr Aleksandrovich Krylov, Irina Vladimirovna Biryukova, Sergei Vladimirovich Mashko
  • Method for producing a lower alkyl ester of ?-L-aspartyl-L-phenylalanine
    Patent number: 7935506
    Abstract: A method for producing lower alkyl ester of ?-L-aspartyl-L-phenylalanine by cultivating a recombinant Escherichia coli bacterium that has the ability to produce and accumulate an aromatic L-amino acid according in a culture medium to produce and accumulate L-phenylalanine in the medium and synthesizing lower alkyl ester of ?-L-aspartyl-L-phenylalanine from the aspartic acid or its derivative and the obtained L-phenylalanine.
    Type: Grant
    Filed: September 29, 2009
    Date of Patent: May 3, 2011
    Assignee: Ajinomoto Co., Inc.
    Inventors: Maria Viacheslavovna Vitushkina, Vitaliy Arkadyevich Livshits, Sergei Vladimirovich Mashko, Vera Georgievna Doroshenko, Irina Vladimirovna Biryukova, Zhanna Iosifovna Katashkina, Aleksandra Yurievna Skorokhodova, Alla Valentinovna Belareva
  • Method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family with attenuated expression of the ydiN gene or the ydiB gene or combination thereof
    Patent number: 7820415
    Abstract: The present invention provides a method for producing an aromatic L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus Escherichia or Pantoea, which has been modified to attenuate expression of the ydiN gene, the ydiB gene, or both.
    Type: Grant
    Filed: February 17, 2009
    Date of Patent: October 26, 2010
    Assignee: Ajinomoto Co., Inc.
    Inventors: Andrey Yurievich Gulevich, Tatyana Aleksandrovna Gaydenko, Vladimir Yurievich Ermishev, Aleksandra Yurievna Skorokhodova, Irina Vladimirovna Biryukova, Sergei Vladimirovich Mashko
  • Method for producing L-amino acids using bacteria belonging to the genus escherichia
    Publication number: 20100099153
    Abstract: A method for producing lower alkyl ester of ?-L-aspartyl-L-phenylalanine by cultivating a recombinant Escherichia coli bacterium that has the ability to produce and accumulate an aromatic L-amino acid according in a culture medium to produce and accumulate L-phenylalanine in the medium and synthesizing lower alkyl ester of ?-L-aspartyl-L-phenylalanine from the aspartic acid or its derivative and the obtained L-phenylalanine.
    Type: Application
    Filed: September 29, 2009
    Publication date: April 22, 2010
    Applicant: Ajinomoto Co., Inc.
    Inventors: Maria Viacheslavovna Vitushkina, Vitaliy Arkadyevich Livshits, Sergei Vladimirovich Mashko, Vera Georgievna Doroshenko, Irina Vladimirovna Biryukova, Zhanna Iosifovna Katashkina, Aleksandra Yurievna Skorokhodova, Alla Valentinovna Belareva
  • bacteria transformed with the yddG gene to enhance L-amino acid producing activity
    Patent number: 7666655
    Abstract: The present invention relates to a method for producing L-amino acid, such as L-phenylalanine and L-tryptophan, is provided using bacterium belonging to the genus Escherichia wherein the L-amino acid productivity of said bacterium is enhanced by enhancing an activity of protein encoded by the yddG gene from Escherichia coli, wherein said protein has an activity to make said bacterium resistant to L-phenylalanine, a phenylalanine analogue, or a tryptophan analogue. The present invention further relates to a method for producing lower alkyl ester of ?-L-aspartyl-L-phenylalanine.
    Type: Grant
    Filed: November 25, 2002
    Date of Patent: February 23, 2010
    Assignee: Ajinomoto Co., Inc.
    Inventors: Maria Viacheslavovna Vitushkina, Vitaliy Arkadyevich Livshits, Sergei Vladimirovich Mashko, Vera Georgievna Doroshenko, Irina Vladimirovna Biryukova, Zhanna Iosifovna Katashkina, Aleksandra Yurievna Skorokhodova, Alla Valentinovna Belareva
  • METHOD FOR CONSTRUCTING AN OPERON CONTAINING TRANSLATIONALLY COUPLED GENES
    Publication number: 20090226919
    Abstract: The present invention provides a method for constructing recombinant translationally coupled operons, a method for producing useful metabolites using the bacterium containing the coupled operons, and a method for monitoring gene expression.
    Type: Application
    Filed: February 19, 2009
    Publication date: September 10, 2009
    Inventors: Andrey Yurievich Gulevich, Aleksandra Yurievna Skorokhodova, Vladimir Yurievich Ermishev, Natalya Igorevna Minaeva, Danila Vadimovich Zimenkov, Aleksandr Aleksandrovich Krylov, Irina Vladimirovna Biryukova, Sergei Vladimirovich Mashko
  • METHOD FOR PRODUCING AN L-AMINO ACID USING A BACTERIUM OF THE ENTEROBACTERIACEAE FAMILY WITH ATTENUATED EXPRESSION OF THE ydiN GENE OR THE ydiB GENE OR COMBINATION THEREOF
    Publication number: 20090191601
    Abstract: The present invention provides a method for producing an aromatic L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus Escherichia or Pantoea, which has been modified to attenuate expression of the ydiN gene, the ydiB gene, or both.
    Type: Application
    Filed: February 17, 2009
    Publication date: July 30, 2009
    Inventors: Andrey Yurievich Gulevich, Tatyana Aleksandrovna Gaydenko, Vladimir Yurievich Ermishev, Aleksandra Yurievna Skorokhodova, Irina Vladimirovna Biryukova, Sergei Vladimirovich Mashko
  • Method for producing L-amino acids using bacteria belonging to the genus escherichia
    Publication number: 20030157667
    Abstract: A method for producing L-amino acid, such as L-phenylalanine and L-tryptophan, is provided using bacterium belonging to the genus Escherichia wherein the L-amino acid productivity of said bacterium is enhanced by enhancing an activity of protein encoded by the yddG gene.
    Type: Application
    Filed: November 25, 2002
    Publication date: August 21, 2003
    Applicant: Ajinomoto Co., Inc.
    Inventors: Maria Viacheslavovna Vitushkina, Vitaliy Arkadyevich Livshits, Sergei Vladimirovich Mashko, Vera Georgievna Doroshenko, Irina Vladimirovna Biryukova, Zhanna Iosifovna Katashkina, Aleksandra Yurievna Skorokhodova, Alla Valentinovna Belareva