Patents by Inventor Irini Manoli

Irini Manoli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biomarkers of organic acidemias
    Patent number: 11372004
    Abstract: Methods of using biomarkers in determining the efficacy of a treatment for an organic acidemia in a subject are disclosed herein. Methods of using biomarkers in determining the efficacy of a liver-directed treatment for an organic acidemia in a subject are likewise disclosed herein.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: June 28, 2022
    Assignee: The United States of America, as represented by the Secretary Department of Health and Human Services
    Inventors: Charles P. Venditti, Irini Manoli
  • N-acetyl mannosammine as a therapeutic agent
    Patent number: 10953026
    Abstract: The invention relates to compositions and methods for treating kidney and muscle dysfunction that involves use of therapeutic amounts of N-acetyl mannosamine.
    Type: Grant
    Filed: May 20, 2019
    Date of Patent: March 23, 2021
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Marjan Huizing, William A. Gahl, Irini Manoli, Enriko Klootwijk
  • ISOTOPIC BIOMARKERS OF ORGANIC ACIDEMIAS
    Publication number: 20200345268
    Abstract: Methods of using isotopic biomarkers in determining the efficacy of a treatment for an organic acidemia in a subject are disclosed herein. Methods of using isotopic biomarkers in determining the efficacy of a liver-directed treatment for an organic acidemia in a subject are likewise disclosed herein.
    Type: Application
    Filed: October 31, 2018
    Publication date: November 5, 2020
    Inventors: Charles P. VENDITTI, Irini MANOLI
  • BIOMARKERS OF ORGANIC ACIDEMIAS
    Publication number: 20200217856
    Abstract: Methods of using biomarkers in determining the efficacy of a treatment for an organic acidemia in a subject are disclosed herein. Methods of using biomarkers in determining the efficacy of a liver-directed treatment for an organic acidemia in a subject are likewise disclosed herein.
    Type: Application
    Filed: September 6, 2018
    Publication date: July 9, 2020
    Inventors: Charles P. VENDITTI, Irini MANOLI
  • N-ACETYL MANNOSAMMINE AS A THERAPEUTIC AGENT
    Publication number: 20190374561
    Abstract: The invention relates to compositions and methods for treating kidney and muscle dysfunction that involves use of therapeutic amounts of N-acetyl mannosamine.
    Type: Application
    Filed: May 20, 2019
    Publication date: December 12, 2019
    Applicant: THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Servic
    Inventors: Marjan Huizing, William A. Gahl, Irini Manoli, Enriko Klootwijk
  • N-acetyl mannosammine as a therapeutic agent
    Patent number: 10335426
    Abstract: The invention relates to compositions and methods for treating kidney and muscle dysfunction that involves use of therapeutic amounts of N-acetyl mannosamine.
    Type: Grant
    Filed: September 12, 2017
    Date of Patent: July 2, 2019
    Assignee: THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services
    Inventors: Marjan Huizing, William A. Gahl, Irini Manoli, Enriko Klootwijk
  • N-ACETYL MANNOSAMMINE AS A THERAPEUTIC AGENT
    Publication number: 20180117072
    Abstract: The invention relates to compositions and methods for treating kidney and muscle dysfunction that involves use of therapeutic amounts of N-acetyl mannosamine.
    Type: Application
    Filed: September 12, 2017
    Publication date: May 3, 2018
    Applicant: The United States of America, as represented by the Secretary, Department of Health and Human
    Inventors: Marjan Huizing, William A. Gahl, Irini Manoli, Enriko Klootwijk
  • N-ACETYL MANNOSAMMINE AS A THERAPEUTIC AGENT
    Publication number: 20150290229
    Abstract: The invention relates to compositions and methods for treating kidney and muscle dysfunction that involves use of therapeutic amounts of N-acetyl mannosamine.
    Type: Application
    Filed: June 29, 2015
    Publication date: October 15, 2015
    Applicant: The United States of America, as represented by the Secretary, Department of Health and Human Serv
    Inventors: Marjan Huizing, William A. Gahl, Irini Manoli, Enriko Klootwijk
  • -acetyl mannosamine as a therapeutic agent
    Patent number: 9095597
    Abstract: The invention relates to compositions and methods for treating kidney and muscle dysfunction that involves use of therapeutic amounts of N-acetyl mannosamine.
    Type: Grant
    Filed: March 8, 2013
    Date of Patent: August 4, 2015
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Marjan Huizing, William A. Gahl, Irini Manoli, Enriko Klootwijk
  • N-acetyl mannosamine as a therapeutic agent
    Patent number: 8410063
    Abstract: The invention relates to compositions and methods for treating kidney and muscle dysfunction that involves use of therapeutic amounts of N-acetyl mannosamine.
    Type: Grant
    Filed: May 30, 2008
    Date of Patent: April 2, 2013
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Marjan Huizing, William A. Gahl, Irini Manoli, Enriko Klootwijk
  • N-ACETYL MANNOSAMINE AS A THERAPEUTIC AGENT
    Publication number: 20100249047
    Abstract: The invention relates to compositions and methods for treating kidney and muscle dysfunction that involves use of therapeutic amounts of N-acetyl mannosamine.
    Type: Application
    Filed: May 30, 2008
    Publication date: September 30, 2010
    Inventors: Marjan Huizing, William A. Gahl, Irini Manoli, Enriko Klootwijk