Abstract: A spectral imaging device includes an imager, a scanning stage to establish relative motion between the imager and a sample in a scanning direction and an optical system controlling a light characteristic of a light beam constituting an image of the sample to the imager. The optical system includes a light varying element to receive the light beam and provide an output light beam with spatially varying light characteristic over a cross-section thereof. A set of redirecting optical elements direct light rays from the sample to form the light beam, and to focus the output light beam onto the imager. A controller controls the scanning stage and the imager to capture a plurality of image frames with an overlap including a defined shift that is greater than 1 pixel along the scanning direction between consecutive image frames. A computing device consolidates image data to provide an image of the sample.

Abstract: A spectral imaging device includes an imager, a scanning stage to establish relative motion between the imager and a sample in a scanning direction and an optical system controlling a light characteristic of a light beam constituting an image of the sample to the imager. The optical system includes a light varying element to receive the light beam and provide an output light beam with spatially varying light characteristic over a cross-section thereof. A set of redirecting optical elements direct light rays from the sample to form the light beam, and to focus the output light beam onto the imager. A controller controls the scanning stage and the imager to capture a plurality of image frames with an overlap including a defined shift that is greater than 1 pixel along the scanning direction between consecutive image frames. A computing device consolidates image data to provide an image of the sample.

Abstract: The present invention provides a process for classification of specific cancers and tumors origin through the analysis of the expression patterns of specific microRNAs and nucleic acid molecules relating thereto. Classification according to a microRNA expression framework allows optimization of treatment, and determination of specific therapy.

Abstract: The present invention provides a process for classification of specific cancers and tumors origin through the analysis of the expression patterns of specific microRNAs and nucleic acid molecules relating thereto. Classification according to a microRNA expression framework allows optimization of treatment, and determination of specific therapy.

Abstract: The present invention provides nucleic acid sequences that are used for identification, classification and diagnosis of lung cancers. The present invention further provides microRNA molecules, as well as various nucleic acid molecules relating thereto or derived therefrom, associated with specific types of lung cancers.

Abstract: The present invention provides nucleic acid sequences that are used for identification, classification and diagnosis of lung cancers. The present invention further provides microRNA molecules, as well as various nucleic acid molecules relating thereto or derived therefrom, associated with specific types of lung cancers.

Abstract: The present invention provides a process for classification of cancers and tissues of origin through the analysis of the expression patterns of specific microRNAs and nucleic acid molecules relating thereto. Classification according to a microRNA tree-based expression framework allows optimization of treatment, and determination of specific therapy.