Patents by Inventor Irishi N.N. Namboothiri

Irishi N.N. Namboothiri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SCALED-UP METHODS FOR PURIFYING ANTIBODIES
    Publication number: 20240140988
    Abstract: A method of isolating an antibody is disclosed. The method comprises contacting a hydrophobic chelator, a non-ionic detergent and metal ions so as to generate an aggregate comprising the hydrophobic chelator, the detergent and the metal ions; and contacting the aggregate with a medium comprising the antibody under conditions that allow partitioning of the antibody into the aggregate. Kits for isolating the antibody are also disclosed.
    Type: Application
    Filed: April 16, 2020
    Publication date: May 2, 2024
    Applicants: Ariel Scientific Innovations Ltd., Yeda Research and Development Co. Ltd.
    Inventors: Guy PATCHORNIK, Mordechai SHEVES, Irishi N. N. NAMBOOTHIRI, Gunasekaran DHANDAPANI
  • METHODS OF PURIFYING ANTIBODIES
    Publication number: 20200102372
    Abstract: A method of isolating an antibody is disclosed. The method comprises contacting a hydrophobic chelator, a non-ionic detergent and metal ions so as to generate an aggregate comprising the hydrophobic chelator, the detergent and the metal ions; and contacting the aggregate with a medium comprising the antibody under conditions that allow partitioning of the antibody into the aggregate. Kits for isolating the antibody are also disclosed.
    Type: Application
    Filed: May 9, 2018
    Publication date: April 2, 2020
    Applicants: Ariel Scientific Innovations Ltd., Yeda Research and Development Co. Ltd.
    Inventors: Guy PATCHORNIK, Irishi N. N. NAMBOOTHIRI, Mordechai SHEVES, Assaf HOWARD, Margalit (Maggie) COHEN
  • METHODS OF ANALYZING CELL MEMBRANES
    Publication number: 20180319849
    Abstract: A method of precipitating cell membrane fragments from a cell lysate is disclosed. The method comprises contacting the cell lysate with a hydrophobic chelator and a metal ion under conditions that allow precipitation of the cell membrane fragments. Kits for precipitating cell membrane fragments are also disclosed.
    Type: Application
    Filed: July 12, 2018
    Publication date: November 8, 2018
    Applicants: Ariel-University Research and Development Company Ltd., Yeda Research and Development Co. Ltd., Indian Institute of Technology Bombay
    Inventors: Mordechai Sheves, Irishi N. N. Namboothiri, Guy Patchornik
  • Methods of analyzing cell membranes
    Patent number: 10030224
    Abstract: A method of precipitating cell membrane fragments from a cell lysate is disclosed. The method comprises contacting the cell lysate with a hydrophobic chelator and a metal ion under conditions that allow precipitation of the cell membrane fragments. Kits for precipitating cell membrane fragments are also disclosed.
    Type: Grant
    Filed: November 1, 2015
    Date of Patent: July 24, 2018
    Assignees: Ariel-University Research and Development Company Ltd., Yeda Research and Development Co. Ltd., Indian Institute of Technology Bombay
    Inventors: Mordechai Sheves, Irishi N. N. Namboothiri, Guy Patchornik
  • METHODS OF ANALYZING CELL MEMBRANES
    Publication number: 20170121668
    Abstract: A method of precipitating cell membrane fragments from a cell lysate is disclosed. The method comprises contacting the cell lysate with a hydrophobic chelator and a metal ion under conditions that allow precipitation of the cell membrane fragments. Kits for precipitating cell membrane fragments are also disclosed.
    Type: Application
    Filed: November 1, 2015
    Publication date: May 4, 2017
    Inventors: Mordechai SHEVES, Irishi N.N. NAMBOOTHIRI, Guy PATCHORNIK
  • Curcumin derivatives
    Patent number: 8410177
    Abstract: A compound has Formula VIII where, X is —C(O)R, —C(O)OR, —CN, —NO2, —S(O)2R?, —P(O)(OR)2; each R is individually H, alkyl, or alkenyl; R? is alkyl or akenyl; R1 is aryl, alkenyl, arylalkenyl, heterocyclyl, or heteroaryl; and R2, R3, R4, R5, R6, R7, R8, R9, R10, and R11 are individually H, alkoxy, or hydroxy. In some cases, X is NO2. Pharmaceutical compositions of the compound of Formula VIII with a pharmaceutically acceptable carrier may be prepared. The compounds may be used for inhibition of cyclooxygenase-2.
    Type: Grant
    Filed: March 4, 2010
    Date of Patent: April 2, 2013
    Assignee: Indian Institute of Technology Bombay
    Inventors: Irishi N. N. Namboothiri, Narasimham Ayyagari, Deena Jose
  • CURCUMIN DERIVATIVES
    Publication number: 20110160276
    Abstract: A compound has Formula VIII where, X is —C(O)R, —C(O)OR, —CN, —NO2, —S(O)2R?, —P(O)(OR)2; each R is individually H, alkyl, or alkenyl; R? is alkyl or akenyl; R1 is aryl, alkenyl, arylalkenyl, heterocyclyl, or heteroaryl; and R2, R3, R4, R5, R6, R7, R8, R9, R10, and R11 are individually H, alkoxy, or hydroxy. In some cases, X is NO2. Pharmaceutical compositions of the compound of Formula VIII with a pharmaceutically acceptable carrier may be prepared. The compounds may be used for inhibition of cyclooxygenase-2.
    Type: Application
    Filed: March 4, 2010
    Publication date: June 30, 2011
    Inventors: Irishi N.N. Namboothiri, Narasimham Ayyagari, Deena Jose