Patents by Inventor Irit Alkalay-Snir

Irit Alkalay-Snir has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for identifying compounds that inhibit ubiquitin-mediated proteolysis of i?b
    Patent number: 6905836
    Abstract: Compounds that inhibit ubiquitin-mediated proteolysis of phosphorylated I?B by interfering, directly or indirectly, with the ability of ?-TrCP/E3RS to engage in protein-protein association involving hnRNP-U, are useful as drugs for treating conditions associated with NF-?B activation. Cellular and non-cellular screening methods for identifying such compounds are based on monitoring the association/dissociation of ?-TrCP/E3RS.
    Type: Grant
    Filed: February 10, 2003
    Date of Patent: June 14, 2005
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Yinon Ben-Neriah, Irit Alkalay-Snir, Ada Hatzubai, Etti Ben Shushan, Matti Davis, Avraham Yaron
  • Methods for identifying compounds that inhibit ubiquitin-mediated proteolysis of IkappaB
    Publication number: 20040014026
    Abstract: Compounds that inhibit ubiquitin-mediated proteolysis of phosphorylated I&kgr;B by interfering, directly or indirectly, with the ability of &bgr;-TrCP/E3RS to engage in protein-protein association involving hnRNP-U, are useful as drugs for treating conditions associated with NF-&kgr;B activation. Cellular and non-cellular screening methods for identifying such compounds are based on monitoring the association/dissociation of &bgr;-TrCP/IE3RS.
    Type: Application
    Filed: February 10, 2003
    Publication date: January 22, 2004
    Inventors: Yinon Ben-Neriah, Irit Alkalay-Snir, Ada Hatzubai, Etti Ben Shushan, Matti Davis, Avraham Yaron