Patents by Inventor Irit Reichenstein

Irit Reichenstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210369761
    Abstract: A method of treating a subject having MND is provided. The method comprising administering to the subject a therapeutically effective amount of an agent selected from the group consisting of miR-218, miR-218*, precursor thereof and a polynucleotide sequence encoding miR-218 or miR-218* or precursor thereof, thereby treating the MND in the subject. A method of treating a subject having MND, the method comprising administering to the subject a therapeutically effective amount of an agent capable of downregulating an activity or expression of a gene product selected from the group consisting of KCND2, KCNH1, GABRB2, SLC6A1, SLC6A11, KCNA1, CACNB4, GRIA2, GRIK2, GABRG1 and GRIK3, is also provided.
    Type: Application
    Filed: August 2, 2021
    Publication date: December 2, 2021
    Applicant: Yeda Research and Development Co. Ltd.
    Inventors: Eran HORNSTEIN, Irit REICHENSTEIN, Alon CHEN
  • Publication number: 20200246372
    Abstract: A method of treating a subject having MND is provided. The method comprising administering to the subject a therapeutically effective amount of an agent selected from the group consisting of miR-218, miR-218*, precursor thereof and a polynucleotide sequence encoding miR-218 or miR-218* or precursor thereof, thereby treating the MND in the subject. A method of treating a subject having MND, the method comprising administering to the subject a therapeutically effective amount of an agent capable of downregulating an activity or expression of a gene product selected from the group consisting of KCND2, KCNH1, GABRB2, SLC6A1, SLC6A11, KCNA1, CACNB4, GRIA2, GRIK2, GABRG1 and GRIK3, is also provided.
    Type: Application
    Filed: April 22, 2020
    Publication date: August 6, 2020
    Applicant: Yeda Research and Development Co. Ltd.
    Inventors: Eran HORNSTEIN, Irit REICHENSTEIN, Alon CHEN
  • Publication number: 20180064748
    Abstract: A method of treating a subject having MND is provided. The method comprising administering to the subject a therapeutically effective amount of an agent selected from the group consisting of miR-218, miR-218*, precursor thereof and a polynucleotide sequence encoding miR-218 or miR-218* or precursor thereof, thereby treating the MND in the subject. A method of treating a subject having MND, the method comprising administering to the subject a therapeutically effective amount of an agent capable of downregulating an activity or expression of a gene product selected from the group consisting of KCND2, KCNH1, GABRB2, SLC6A1, SLC6A11, KCNA1, CACNB4, GRIA2, GRIK2, GABRG1 and GRIK3, is also provided.
    Type: Application
    Filed: March 27, 2016
    Publication date: March 8, 2018
    Inventors: Eran HORNSTEIN, Irit REICHENSTEIN, Alon CHEN
  • Publication number: 20150197810
    Abstract: A method of diagnosing Amyotrophic Lateral Sclerosis (ALS) is disclosed. The method comprising determining a level of miR-218 in a biological sample of a subject, wherein a down-regulation in the miR-218 is indicative of ALS in the subject.
    Type: Application
    Filed: March 27, 2015
    Publication date: July 16, 2015
    Inventors: Eran HORNSTEIN, Alon Chen, Irit Reichenstein, Anna Maria Emde