Patents by Inventor Irwin Klein

Irwin Klein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Controlled release pharmaceutical compositions of liothyronine and methods of making and using the same
    Publication number: 20060246133
    Abstract: This invention relates to sustained release pharmaceutical compositions comprising liothyronine, or a salt or derivative thereof. Additionally, the present invention is directed to methods of manufacture and methods of using the pharmaceutical compositions of the present invention.
    Type: Application
    Filed: March 31, 2006
    Publication date: November 2, 2006
    Inventors: Martin Beasley, David Hause, Irwin Klein, Charles Pamplin, David Reynolds, Kevin Sills
  • Methods for treating hypothyroidism
    Publication number: 20050176829
    Abstract: The present invention provides methods for treatment of hypothyroidism in an adult comprising the long-term administration of T3 at a dose of 0.005-0.03 ?g/kg body weight/hour/day or a at daily dose of 5-25 ?g T3 in a sustained-release formulation, in the absence of administration of a therapeutic dose of T4.
    Type: Application
    Filed: September 24, 2004
    Publication date: August 11, 2005
    Inventors: Irwin Klein, Kaie Ojamaa, Sara Danzi
  • Compositions of stable T3 and methodes of use thereof
    Publication number: 20050059574
    Abstract: This invention provides a stable composition containing T3, serum albumin and water, wherein the T3 has a half-life of at least five days, particularly at neutral pH. This invention further provides a method for emergency treatment of a patient with cardiac arrest and with cardiac electrical standstill to restore effective cardiac function, comprising administering to the patient a therapeutically effective amount of the stable composition.
    Type: Application
    Filed: November 30, 2001
    Publication date: March 17, 2005
    Inventors: Irwin Klein, Kaie Ojamaa, Leo Rubin
  • Method for treating hypothyroidism
    Publication number: 20040156893
    Abstract: The present invention provides a method for treatment of hypothyroidism in an adult comprising the long-term administration of T3 at a dose of 0.005-0.03 &mgr;g/kg body weight/hour/day.
    Type: Application
    Filed: February 11, 2003
    Publication date: August 12, 2004
    Inventors: Irwin Klein, Kaie Ojamaa, Sara Danzi
  • Method for treating congestive heart failure
    Patent number: 6288117
    Abstract: The present invention provides a method for chronic treatment of congestive heart failure (CHF) in a patient having CHF, by administering daily, over the long-term, an amount of T3 effective to treat the CHF.
    Type: Grant
    Filed: March 23, 2000
    Date of Patent: September 11, 2001
    Assignee: North Shore-Long Island Jewish Research Institute
    Inventors: Irwin Klein, Kaie Ojamaa