Patents by Inventor Isa Rizk
Isa Rizk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11877762Abstract: A retrieval device can include inwardly facing protruding features that facilitate engagement and capture of a thrombus or other mass from a body lumen of a patient. The protruding features can deploy from a frame of the retrieval device to extend radially inwardly toward an opposing side of the frame. When deployed into a thrombus, the protruding features engage and urge the thrombus as the retrieval device moves to facilitate capture.Type: GrantFiled: October 30, 2020Date of Patent: January 23, 2024Assignee: REFLOW MEDICAL, INC.Inventors: John Fulkerson, Isa Rizk, Jihad Ali Mustapha, Teodoro S. Jimenez, Jr., Patrick Lo
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Publication number: 20230248558Abstract: Delivery systems for expandable elements, such as stents or scaffolds having spikes, flails, or other protruding features for penetrating target tissue and/or delivering drugs within a human patient are described along with associated methods for using such systems. The delivery systems can be provided with a stent that is positioned over an inflatable balloon for expansion and delivery of the stent to a target delivery location. By positioning the stent over and about the inflatable balloon, the stent is ready to be expanded by the balloon immediately upon unsheathing with respect to the outer shaft. Additionally or alternatively, a stent can be positioned in an axially offset arrangement with respect to a balloon to reduce the need for space required by overlapping components.Type: ApplicationFiled: April 14, 2023Publication date: August 10, 2023Inventors: Teodoro S. Jimenez, Jr., Patrick Lo, John Fulkerson, Isa Rizk, Francisco Aguayo, Jihad Ali Mustapha, Gary Ansel
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Patent number: 11648139Abstract: Delivery systems for expandable elements, such as stents or scaffolds having spikes, flails, or other protruding features for penetrating target tissue and/or delivering drugs within a human patient are described along with associated methods for using such systems. The delivery systems can be provided with a stent that is positioned over an inflatable balloon for expansion and delivery of the stent to a target delivery location. By positioning the stent over and about the inflatable balloon, the stent is ready to be expanded by the balloon immediately upon unsheathing with respect to the outer shaft. Additionally or alternatively, a stent can be positioned in an axially offset arrangement with respect to a balloon to reduce the need for space required by overlapping components.Type: GrantFiled: October 4, 2019Date of Patent: May 16, 2023Assignee: REFLOW MEDICAL, INC.Inventors: Teodoro S. Jimenez, Jr., Patrick Lo, John Fulkerson, Isa Rizk, Francisco Aguayo, Jihad Ali Mustapha, Gary Ansel
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Publication number: 20230109591Abstract: Delivery systems for expandable elements, such as stents or scaffolds are described along with associated methods for using such systems. The delivery systems can be provided with a stent and/or a balloon the is enclosed by a sheath that need not extend an entire length of the delivery system. Instead, the sheath can be coupled to a control wire for retraction and advancement of the sheath. By enclosing the stent and/or balloon with a short sheath, the profile of the delivery system is reduced.Type: ApplicationFiled: September 29, 2022Publication date: April 6, 2023Inventors: Teodoro S. Jimenez, Jr., John Fulkerson, Isa Rizk, Francisco Aguayo
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Publication number: 20230091211Abstract: A delivery system can be provided with an ability to change its configurations to achieve both access to target anatomy and treatment thereof. Such treatments can include directing interventional devices around an occlusion. By providing different functionality at different stages, the need to exchange and replace tools at different stages can be reduced or eliminated. Accordingly, such operations can be completed more rapidly, efficiently, and safely.Type: ApplicationFiled: November 21, 2022Publication date: March 23, 2023Inventors: Outhit Bouasaysy, John Fulkerson, Isa Rizk, Fadi Saab
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Patent number: 11565079Abstract: A delivery device can be provided with a low outer profile and high flexibility for navigating tortuous anatomy. An inner lumen defined by a shaft of the delivery device provides adequate space for delivery devices to target anatomy. Additionally, the delivery device maintains the patency of its lumen even when positioned within tortuous anatomy. The turns of filar(s) forming a coil of the shaft adjust their axial spacing relative to each other to avoiding buckling that would otherwise result in a narrowing of the inner lumen.Type: GrantFiled: August 13, 2020Date of Patent: January 31, 2023Assignee: REFLOW MEDICAL, INC.Inventors: Outhit Bouasaysy, Isa Rizk, John Fulkerson
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Patent number: 11504142Abstract: A delivery system can be provided with an ability to change its configurations to achieve both access to target anatomy and treatment thereof. Such treatments can include directing interventional devices around an occlusion. By providing different functionality at different stages, the need to exchange and replace tools at different stages can be reduced or eliminated. Accordingly, such operations can be completed more rapidly, efficiently, and safely.Type: GrantFiled: August 13, 2020Date of Patent: November 22, 2022Assignee: ReFlow Medical, Inc.Inventors: Outhit Bouasaysy, John Fulkerson, Isa Rizk, Fadi Saab
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Patent number: 11253379Abstract: Expandable elements having drug-delivery features and associated systems and methods are disclosed herein. In one embodiment, a drug-eluting stent includes a radially expandable cylindrical frame having a plurality of struts. The frame is transformable between a low-profile delivery state and an expanded deployed state. A plurality of drug-delivery features are carried by one of the struts and configured to deliver a drug to a treatment site within the patient or piercing through the tissue wall to break the constricting of the vessel wall inwardly. When the frame is in the expanded state within a body lumen of the patient, the drug-delivery features extend radially outwardly away from the strut and are configured to engage and, in some arrangements, pass through a wall of the body lumen.Type: GrantFiled: March 6, 2019Date of Patent: February 22, 2022Assignee: ReFlow Medical, Inc.Inventors: John Fulkerson, Isa Rizk, Jihad Ali Mustapha, Teodoro S. Jimenez, Jr.
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Publication number: 20210128330Abstract: A stent can include outwardly facing protruding features that facilitate engagement with a wall of a body vessel. The protruding features can deploy from a frame of the stent to extend radially outwardly. When deployed into a body vessel, the protruding features engage and anchor against the wall of the body vessel to ensure accurate and secure placement of the stent.Type: ApplicationFiled: November 4, 2020Publication date: May 6, 2021Inventors: John Fulkerson, Isa Rizk, Jihad Ali Mustapha, Teodoro S. Jimenez, JR.
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Publication number: 20210128184Abstract: A retrieval device can include inwardly facing protruding features that facilitate engagement and capture of a thrombus or other mass from a body lumen of a patient. The protruding features can deploy from a frame of the retrieval device to extend radially inwardly toward an opposing side of the frame. When deployed into a thrombus, the protruding features engage and urge the thrombus as the retrieval device moves to facilitate capture.Type: ApplicationFiled: October 30, 2020Publication date: May 6, 2021Inventors: John Fulkerson, Isa Rizk, Jihad Ali Mustapha, Teodoro S. Jimenez, JR., Patrick LO
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Publication number: 20210045757Abstract: A delivery system can be provided with an ability to change its configurations to achieve both access to target anatomy and treatment thereof. Such treatments can include directing interventional devices around an occlusion. By providing different functionality at different stages, the need to exchange and replace tools at different stages can be reduced or eliminated. Accordingly, such operations can be completed more rapidly, efficiently, and safely.Type: ApplicationFiled: August 13, 2020Publication date: February 18, 2021Inventors: Outhit Bouasaysy, John Fulkerson, Isa Rizk, Fadi Saab
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Publication number: 20210046279Abstract: A delivery device can be provided with a low outer profile and high flexibility for navigating tortuous anatomy. An inner lumen defined by a shaft of the delivery device provides adequate space for delivery devices to target anatomy. Additionally, the delivery device maintains the patency of its lumen even when positioned within tortuous anatomy. The turns of filar(s) forming a coil of the shaft adjust their axial spacing relative to each other to avoiding buckling that would otherwise result in a narrowing of the inner lumen.Type: ApplicationFiled: August 13, 2020Publication date: February 18, 2021Inventors: Outhit Bouasaysy, Isa Rizk, John Fulkerson
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Patent number: 10799255Abstract: Methods for treating a patient using intravascular devices, systems, and methods are disclosed herein. One aspect of the present technology is directed to an intravascular device having an elongated member coupled to and extending between a handle and an angled distal portion. The distal portion is moveable between a first configuration having a first shape configured for intravascular delivery and a second configuration having a second shape, different than the first shape, that is configured for intravascular delivery.Type: GrantFiled: August 27, 2014Date of Patent: October 13, 2020Assignee: REFLOW MEDICAL, INC.Inventors: Isa Rizk, John Fulkerson, Mahmood Razavi
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Publication number: 20200107947Abstract: Delivery systems for expandable elements, such as stents or scaffolds having spikes, flails, or other protruding features for penetrating target tissue and/or delivering drugs within a human patient are described along with associated methods for using such systems. The delivery systems can be provided with a stent that is positioned over an inflatable balloon for expansion and delivery of the stent to a target delivery location. By positioning the stent over and about the inflatable balloon, the stent is ready to be expanded by the balloon immediately upon unsheathing with respect to the outer shaft. Additionally or alternatively, a stent can be positioned in an axially offset arrangement with respect to a balloon to reduce the need for space required by overlapping components.Type: ApplicationFiled: October 4, 2019Publication date: April 9, 2020Inventors: Teodoro S. Jimenez, JR., Patrick Lo, John Fulkerson, Isa Rizk, Francisco Aguayo, Jihad Ali Mustapha, Gary Ansel
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Publication number: 20190201219Abstract: Expandable elements having drug-delivery features and associated systems and methods are disclosed herein. In one embodiment, a drug-eluting stent includes a radially expandable cylindrical frame having a plurality of struts. The frame is transformable between a low-profile delivery state and an expanded deployed state. A plurality of drug-delivery features are carried by one of the struts and configured to deliver a drug to a treatment site within the patient or piercing through the tissue wall to break the constricting of the vessel wall inwardly. When the frame is in the expanded state within a body lumen of the patient, the drug-delivery features extend radially outwardly away from the strut and are configured to engage and, in some arrangements, pass through a wall of the body lumen.Type: ApplicationFiled: March 6, 2019Publication date: July 4, 2019Inventors: John Fulkerson, Isa Rizk, Jihad Ali Mustapha, Teodoro S. Jimenez
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Patent number: 10258487Abstract: Expandable elements having drug-delivery features and associated systems and methods are disclosed herein. In one embodiment, a drug-eluting stent includes a radially expandable cylindrical frame having a plurality of struts. The frame is transformable between a low-profile delivery state and an expanded deployed state. A plurality of drug-delivery features are carried by one of the struts and configured to deliver a drug to a treatment site within the patient or piercing through the tissue wall to break the constricting of the vessel wall inwardly. When the frame is in the expanded state within a body lumen of the patient, the drug-delivery features extend radially outwardly away from the strut and are configured to engage and, in some arrangements, pass through a wall of the body lumen.Type: GrantFiled: March 27, 2017Date of Patent: April 16, 2019Assignee: REFLOW MEDICAL, INC.Inventors: John Fulkerson, Isa Rizk, Jihad Ali Mustapha, Teodoro S. Jimenez, Jr.
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Patent number: 10172729Abstract: Expandable elements having drug-delivery features and associated systems and methods are disclosed herein. In one embodiment, a drug-eluting stent includes a radially expandable cylindrical frame having a plurality of struts. The frame is transformable between a low-profile delivery state and an expanded deployed state. A plurality of drug-delivery features are carried by one of the struts and configured to deliver a drug to a treatment site within the patient or piercing through the tissue wall to break the constricting of the vessel wall inwardly. When the frame is in the expanded state within a body lumen of the patient, the drug-delivery features extend radially outwardly away from the strut and are configured to engage and, in some arrangements, pass through a wall of the body lumen.Type: GrantFiled: October 12, 2016Date of Patent: January 8, 2019Assignee: REFLOW MEDICAL, INC.Inventors: John Fulkerson, Isa Rizk, Jihad Ali Mustapha, Teodoro S. Jimenez, Jr.
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Publication number: 20180289517Abstract: Delivery systems for expandable elements, such as stents or scaffolds having spikes, flails, or other protruding features for delivering drugs and/or penetrating target tissue within a human patient and associated methods for using such systems. The delivery systems can be configured to deliver and position expandable structures within a body lumen (e.g., vessel). In addition, these delivery systems can also be configured to deploy and expand the expandable structures in the body lumen. The delivery systems can further be configured to engage with the expanded structure and collapse the structure for removal from the body lumen. The delivery systems can be configured to deliver another expandable structure or the same expandable structure to another body lumen, or the same body lumen, in a single procedure or during a plurality of procedures.Type: ApplicationFiled: April 6, 2018Publication date: October 11, 2018Inventors: Teodoro S. Jimenez, John Fulkerson, Isa Rizk, Jihad Ali Mustapha
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Publication number: 20170196717Abstract: Expandable elements having drug-delivery features and associated systems and methods are disclosed herein. In one embodiment, a drug-eluting stent includes a radially expandable cylindrical frame having a plurality of struts. The frame is transformable between a low-profile delivery state and an expanded deployed state. A plurality of drug-delivery features are carried by one of the struts and configured to deliver a drug to a treatment site within the patient or piercing through the tissue wall to break the constricting of the vessel wall inwardly. When the frame is in the expanded state within a body lumen of the patient, the drug-delivery features extend radially outwardly away from the strut and are configured to engage and, in some arrangements, pass through a wall of the body lumen.Type: ApplicationFiled: March 27, 2017Publication date: July 13, 2017Inventors: John Fulkerson, Isa Rizk, Jihad Ali Mustapha, Teodoro S. Jimenez, JR.
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Publication number: 20170100266Abstract: Expandable elements having drug-delivery features and associated systems and methods are disclosed herein. In one embodiment, a drug-eluting stent includes a radially expandable cylindrical frame having a plurality of struts. The frame is transformable between a low-profile delivery state and an expanded deployed state. A plurality of drug-delivery features are carried by one of the struts and configured to deliver a drug to a treatment site within the patient or piercing through the tissue wall to break the constricting of the vessel wall inwardly. When the frame is in the expanded state within a body lumen of the patient, the drug-delivery features extend radially outwardly away from the strut and are configured to engage and, in some arrangements, pass through a wall of the body lumen.Type: ApplicationFiled: October 12, 2016Publication date: April 13, 2017Inventors: John Fulkerson, Isa Rizk, Jihad Ali Mustapha, Teodoro S. Jimenez, JR.