Patents by Inventor Isaac A. Angres

Isaac A. Angres has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210400979
    Abstract: The invention provides a filter fabric for providing anti pathogenic properties which has been coated with a composition comprising (a) 0.0001-99.9999% by weight of a compound of such as zinc pyrithione and (b) 0.0001-99.9999% by weight of an additional zinc salt selected from the group consisting of zinc acetate, zinc propionate, zinc oxalate, zinc benzoate, zinc gluconate, zinc ascorbate, zinc citrate, zinc lactate, zinc glycolate, zinc maleate, zinc fumarate, zinc polyacrylate and zinc polymaleate.
    Type: Application
    Filed: June 26, 2020
    Publication date: December 30, 2021
    Inventors: Isaac Angres, Carlos Salazar Altamar
  • Patent number: 10663470
    Abstract: The invention provides a method of detecting the presence or absence of a disease in a patient wherein said disease is accompanied by deficient levels of S-adenosylmethionine comprising: identifying a patient that is suspected of having said disease or is at risk of having said disease; obtaining a biological sample from said patient; determining the level of S-adenosylmethionine in said biological sample using an antibody derived from a hapten analog of S-adenosylmethionine; and correlating the level of S-adenosylmethionine in said biological sample with the presence, absence, or severity of said disease. The invention also provides methods for measuring SAH which is used to determine the methylation index (ratio of SAM/SAH) in biological fluids which is indicative of the health status of an individual. Additionally, the invention includes test strips which are useful for determining S-adenosylmethionine and S-adenosylhomocysteine.
    Type: Grant
    Filed: April 30, 2018
    Date of Patent: May 26, 2020
    Assignee: HUNAN SKYWORLD BIOTECHNOLOGIES CO
    Inventors: Xiujuan Hao, Isaac Angres
  • Patent number: 10656159
    Abstract: The invention provides a method of detecting the presence, absence or severity of a disease in a patient wherein said disease is accompanied by decreased level of S-adenosylmethionine, or increased level of S-adenosylhomocysterine, or reduced methylation index comprising: identifying any individual or a patient that is suspected of having said disease or is at risk of having said disease; obtaining a biological sample from said patient; determining the level of SAM in said biological sample using an antibody derived from a hapten analog of SAM, SAH; and correlating the levels of SAM, SAH and MI in said biological sample with the presence, absence, or severity of said disease. The invention also provides methods for determining methylation index in biological fluids which is indicative of the health status of an individual. Additionally, the invention includes colloidal gold test strips and homogenous enzyme immunoassays which are useful for determining S-adenosylmethionine and S-adenosylhomocysteine.
    Type: Grant
    Filed: February 5, 2018
    Date of Patent: May 19, 2020
    Assignee: HUNAN SKYWORLD BIOTECHNOLOGIES CO
    Inventors: Xiujuan Hao, Isaac A Angres
  • Publication number: 20180246110
    Abstract: The invention provides a method of detecting the presence or absence of a disease in a patient wherein said disease is accompanied by deficient levels of S-adenosylmethionine comprising: identifying a patient that is suspected of having said disease or is at risk of having said disease; obtaining a biological sample from said patient; determining the level of S-adenosylmethionine in said biological sample using an antibody derived from a hapten analog of S-adenosylmethionine; and correlating the level of S-adenosylmethionine in said biological sample with the presence, absence, or severity of said disease. The invention also provides methods for measuring SAH which is used to determine the methylation index (ratio of SAM/SAH) in biological fluids which is indicative of the health status of an individual. Additionally, the invention includes test strips which are useful for determining S-adenosylmethionine and S-adenosylhomocysteine.
    Type: Application
    Filed: April 30, 2018
    Publication date: August 30, 2018
    Inventors: Xiujuan Hao, Isaac Angres
  • Publication number: 20180169128
    Abstract: A method of detecting the presence or absence of a disease in a patient wherein said disease is accompanied by deficient levels of S-adenosylmethionine comprising: identifying a patient that is suspected of having said disease or is at risk of having said disease; obtaining a biological sample from said patient; determining the level of S-adenosylmethionine in said biological sample using an antibody derived from a hapten analog of S-adenosylmethionine; and correlating the level of S-adenosylmethionine in said biological sample with the presence or absence of said disease. The invention also provides methods for measuring SAH which is used to determine the methylation index (ratio of SAM/SAH) in biological fluids which is indicative of the health status of an individual.
    Type: Application
    Filed: January 29, 2018
    Publication date: June 21, 2018
    Inventors: Xiujuan Hao, Isaac Angres
  • Publication number: 20180156816
    Abstract: The invention provides a method of detecting the presence, absence or severity of a disease in a patient wherein said disease is accompanied by decreased level of S-adenosylmethionine, or increased level of S-adenosylhomocysterine, or reduced methylation index comprising: identifying any individual or a patient that is suspected of having said disease or is at risk of having said disease; obtaining a biological sample from said patient; determining the level of SAM in said biological sample using an antibody derived from a hapten analog of SAM, SAH; and correlating the levels of SAM, SAH and MI in said biological sample with the presence, absence, or severity of said disease. The invention also provides methods for determining methylation index in biological fluids which is indicative of the health status of an individual. Additionally, the invention includes colloidal gold test strips and homogenous enzyme immunoassays which are useful for determining S-adenosylmethionine and S-adenosylhomocysteine.
    Type: Application
    Filed: February 5, 2018
    Publication date: June 7, 2018
    Inventors: Xiujuan Hao, Isaac A Angres
  • Patent number: 9958447
    Abstract: The invention provides a method of detecting the presence or absence of a disease in a patient wherein said disease is accompanied by deficient levels of S-adenosylmethionine comprising: identifying a patient that is suspected of having said disease or is at risk of having said disease; obtaining a biological sample from said patient; determining the level of S-adenosylmethionine in said biological sample using an antibody derived from a hapten analog of S-adenosylmethionine; and correlating the level of S-adenosylmethionine in said biological sample with the presence, absence, or severity of said disease. The invention also provides methods for measuring SAH which is used to determine the methylation index (ratio of SAM/SAH) in biological fluids which is indicative of the health status of an individual. Additionally, the invention includes test strips which are useful for determining S-adenosylmethionine and S-adenosylhomocysteine.
    Type: Grant
    Filed: August 11, 2014
    Date of Patent: May 1, 2018
    Assignee: HUNAN SKYWORLD BIOTECHNOLOGIES CO
    Inventors: Xiujuan Hao, Isaac A Angres
  • Patent number: 9890988
    Abstract: A robust, durable, easy to use, reusable shipping container is disclosed that is capable of protecting contents from surrounding high temperatures up to 1000 degrees Fahrenheit for a minimum of at least three and a half hours. The container includes an inner chamber surrounded by an outer chamber. A phase change liquid (PCL) is sequestered in a porous support matrix contained in the inner chamber, while the outer chamber is filled with high temperature insulation, forming an outer barrier layer that is designed to reduce heat flux into the inner chamber.
    Type: Grant
    Filed: November 16, 2016
    Date of Patent: February 13, 2018
    Assignee: BAE Systems plc
    Inventors: Charles A Howland, Jeremy Branson, Isaac Angres
  • Patent number: 9885723
    Abstract: The invention provides a method of detecting the presence, absence or severity of a disease in a patient wherein said disease is accompanied by decreased level of S-adenosylmethionine, or increased level of S-adenosylhomocysterine, or reduced methylation index comprising: identifying any individual or a patient that is suspected of having said disease or is at risk of having said disease; obtaining a biological sample from said patient; determining the level of SAM in said biological sample using an antibody derived from a hapten analog of SAM, SAH; and correlating the levels of SAM, SAH and MI in said biological sample with the presence, absence, or severity of said disease. The invention also provides methods for determining methylation index in biological fluids which is indicative of the health status of an individual. Additionally, the invention includes colloidal gold test strips and homogenous enzyme immunoassays which are useful for determining S-adenosylmethionine and S-adenosylhomocysteine.
    Type: Grant
    Filed: June 7, 2015
    Date of Patent: February 6, 2018
    Assignee: HUNAN SKYWORLD BIOTECHNOLOGIES CO
    Inventors: Xiujuan Hao, Isaac A Angres
  • Patent number: 9877982
    Abstract: A method of detecting the presence or absence of a disease in a patient wherein said disease is accompanied by deficient levels of S-adenosylmethionine comprising: identifying a patient that is suspected of having said disease or is at risk of having said disease; obtaining a biological sample from said patient; determining the level of S-adenosylmethionine in said biological sample using an antibody derived from a hapten analog of S-adenosylmethionine; and correlating the level of S-adenosylmethionine in said biological sample with the presence or absence of said disease. The invention also provides methods for measuring SAH which is used to determine the methylation index (ratio of SAM/SAH) in biological fluids which is indicative of the health status of an individual.
    Type: Grant
    Filed: March 18, 2014
    Date of Patent: January 30, 2018
    Assignee: Hunan SkyWorld Biotechnologies Co. LTD
    Inventors: Xiujuan Hao, Isaac A Angres
  • Publication number: 20170314835
    Abstract: A robust, durable, easy to use, reusable shipping container is disclosed that is capable of protecting contents from surrounding high temperatures up to 1000 degrees Fahrenheit for a minimum of at least three and a half hours. The container includes an inner chamber surrounded by an outer chamber. A phase change liquid (PCL) is sequestered in a porous support matrix contained in the inner chamber, while the outer chamber is filled with high temperature insulation, forming an outer barrier layer that is designed to reduce heat flux into the inner chamber.
    Type: Application
    Filed: November 16, 2016
    Publication date: November 2, 2017
    Inventors: Charles A. Howland, Jeremy Branson, Isaac Angres
  • Publication number: 20160041154
    Abstract: The invention provides a method of detecting the presence, absence or severity of a disease in a patient wherein said disease is accompanied by decreased level of S-adenosylmethionine, or increased level of S-adenosylhomocysterine, or reduced methylation index comprising: identifying any individual or a patient that is suspected of having said disease or is at risk of having said disease; obtaining a biological sample from said patient; determining the level of SAM in said biological sample using an antibody derived from a hapten analog of SAM, SAH; and correlating the levels of SAM, SAH and MI in said biological sample with the presence, absence, or severity of said disease. The invention also provides methods for determining methylation index in biological fluids which is indicative of the health status of an individual. Additionally, the invention includes colloidal gold test strips and homogenous enzyme immunoassays which are useful for determining S-adenosylmethionine and S-adenosylhomocysteine.
    Type: Application
    Filed: June 7, 2015
    Publication date: February 11, 2016
    Inventors: Xiujuan Hao, Isaac A. Angres
  • Publication number: 20150268231
    Abstract: The invention provides a method of detecting the presence or absence of a disease in a patient wherein said disease is accompanied by deficient levels of S-adenosylmethionine comprising: identifying a patient that is suspected of having said disease or is at risk of having said disease; obtaining a biological sample from said patient; determining the level of S-adenosylmethionine in said biological sample using an antibody derived from a hapten analog of S-adenosylmethionine; and correlating the level of S-adenosylmethionine in said biological sample with the presence, absence, or severity of said disease. The invention also provides methods for measuring SAH which is used to determine the methylation index (ratio of SAM/SAH) in biological fluids which is indicative of the health status of an individual. Additionally, the invention includes test strips which are useful for determining S-adenosylmethionine and S-adenosylhomocysteine.
    Type: Application
    Filed: August 11, 2014
    Publication date: September 24, 2015
    Inventors: Xiujuan Hao, Isaac A. Angres
  • Publication number: 20140356423
    Abstract: The present invention provides a pharmaceutical formulation suitable for filling softgel capsules comprising: (a) from about 1% to about 90% by weight of a bisphosphonic acid or a pharmaceutically acceptable salt; (b) from 1% to about 99% by weight of lycopene and (c) from about 40% to about 80% by weight of a liquid carrier comprising 50% to 80% by weight polyethylene glycol; 5% to 15% by weight of glycerin; and 5% to 20% by weight water. The invention also describes a method for preparing alendronate or its pharmaceutical acceptable salts in encapsulated therapeutic dosage form in combination with lycopene.
    Type: Application
    Filed: May 28, 2013
    Publication date: December 4, 2014
    Inventor: Isaac A. Angres
  • Publication number: 20140271945
    Abstract: A method of detecting the presence or absence of a disease in a patient wherein said disease is accompanied by deficient levels of S-adenosylmethionine comprising: identifying a patient that is suspected of having said disease or is at risk of having said disease; obtaining a biological sample from said patient; determining the level of S-adenosylmethionine in said biological sample using an antibody derived from a hapten analog of S-adenosylmethionine; and correlating the level of S-adenosylmethionine in said biological sample with the presence or absence of said disease. The invention also provides methods for measuring SAH which is used to determine the methylation index (ratio of SAM/SAH) in biological fluids which is indicative of the health status of an individual.
    Type: Application
    Filed: March 18, 2014
    Publication date: September 18, 2014
    Inventors: Xiujuan Hao, Isaac A. Angres
  • Patent number: 8309024
    Abstract: A system for non-destructive determination of the degree of fluorination in carbon monofluoride (CFx) during the process of CFx synthesis is described. The system includes a measuring generator containing a capacitive sensor for measuring a respective capacitance, a base generator containing a capacitive sensor for measuring a base capacitance, and a processor for determining a difference between the respective capacitance and the base capacitance. The system is configured to determine the degree of fluorination based on the difference between the respective capacitance and the base capacitance.
    Type: Grant
    Filed: April 23, 2009
    Date of Patent: November 13, 2012
    Assignee: Enerize Corporation
    Inventors: Volodymyr I Redko, Elena M Shembel, Volodymyr S Khandetskyy, Dayal T Meshri, Isaac A Angres, Robert Adams, Dmytro Sivtsov, Oxana V Redko, Tymofiy V Pastushkin
  • Publication number: 20090267623
    Abstract: The present invention is a method and related automatic system for non-destructive determination of physical-chemical properties of powdered in particular as related to the quality control of powdered materials used in battery industry, for example determination of carbon monofluoride (CFx) degree of fluorination during the process of CFx synthesis.
    Type: Application
    Filed: April 23, 2009
    Publication date: October 29, 2009
    Applicant: Enerize Corporation
    Inventors: Volodymyr I. Redko, Elena M. Shembel, Volodymyr S. Khandetskyy, Dayal T. Meshri, Isaac A. Angres, Robert Adams, Dmytro Sivtsov, Oxana V. Red'ko, Tymofiy V. Pastushkin
  • Patent number: 6890941
    Abstract: The present invention provides pharmaceutical compositions, methods, combinations, and kits for treating a disorder related to elevated serum cholesterol concentration, for example, hypercholesterolemia, atherosclerosis, elevated LDL plasma levels, low HDL plasma levels, hypertriglyceridemia, hyperlipidemia, hypertension, cholesterol gallstones, and lipid storage diseases. The compositions, methods, combinations, and kits of the present invention are pharmaceutical compositions comprising atherapeutically effective amount of a lipid regulating agent, such as a HMG-CoA reductase inhibitor, and compound that inhibits cholesterol synthesis at a point between the formation of acetate and mevalonate. A typical pharmaceutical composition of the invention contains and effective amount of atorvastatin and an effective amount of policosanol.
    Type: Grant
    Filed: December 3, 2003
    Date of Patent: May 10, 2005
    Assignee: Procaps S.A.
    Inventors: Isaac A. Angres, Ruben Minski, Meyer Minski
  • Patent number: 6001828
    Abstract: A pharmaceutical composition comprising: (a) a tumor necrosis factor inhibitor; (b) a compound selected from the group consisting of reverse transcriptase inhibitors, protease inhibitor, a gene inhibitor, myristoylation inhibitors, cell-virus binding inhibitors, LTR promoter site inhibitors, ribosome inactivators, platelet aggregation inhibitors and prophylactic and therapeutic HIV vaccines, and (c) a pharmaceutical inert nontoxic carrier are described.
    Type: Grant
    Filed: October 23, 1997
    Date of Patent: December 14, 1999
    Inventors: Peter Andrulis, Jr., Isaac A. Angres
  • Patent number: 5179097
    Abstract: Novel choline salts of non-steroidal anti-inflammatory carboxylic acids and anti-lipidemic carboxylic acids are described. Additionally, blends of choline salts with the above carboxylic acids are also described. The new salts and compositions offer new therapeutic advantages.
    Type: Grant
    Filed: June 10, 1991
    Date of Patent: January 12, 1993
    Inventor: Isaac A. Angres