Patents by Inventor Isaac Cann

Isaac Cann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACEUTICAL COMPOSITION FOR AMELIORATING ACUTE LUNG INJURY AND ACUTE WORSENING OF PULMONARY FIBROSIS
    Publication number: 20260116957
    Abstract: Provided are a monoclonal antibody molecule or a derivative thereof against corisin and a pharmaceutical composition containing the same for ameliorating acute lung injury and acute exacerbation of pulmonary fibrosis. The pharmaceutical composition of the present invention contains a monoclonal antibody molecule or a derivative thereof against corisin, which is a peptide conserved in diverse Staphylococci, such as Staphylococcus nepalensis.
    Type: Application
    Filed: March 18, 2022
    Publication date: April 30, 2026
    Inventors: Esteban Gabazza, Corina Gabazza, Isaac Cann
  • METHODS AND COMPOSITIONS FOR EVALUATING AND TREATING FIBROSIS
    Publication number: 20230357373
    Abstract: Staphylococcus nepalensis releases corisin, a peptide conserved in diverse Staphylococci, that induces apoptosis of lung epithelial cells. Therefore, methods and apparatus for detecting the presence of corisin in a biological sample of a patient are disclosed, as well as pharmaceutical compositions, such as antibodies, and methods for treating patents having or suspected of having fibrosis.
    Type: Application
    Filed: December 16, 2020
    Publication date: November 9, 2023
    Applicants: Mie University, The Board of Trustees of the University of Illinois
    Inventors: Esteban Gabazza, Corina D'Alessandro-Gabazza, Isaac Cann
  • DNA synthetase
    Patent number: 7211647
    Abstract: The object of the invention is to provide proteins that have both DNA primase activity and DNA polymerase activity. This subject is solved by a protein (p41) that has an amino acid sequence shown in SEQ ID NO: 1. This is for the first time that proteins that have both DNA primase activity and DNA polymerase activity were found. A protein (p46) that has amino acid sequence shown in SEQ ID NO: 2 forms a complex with p41, and enforces DNA synthesis activity that is independent and/or dependent from primer of p41.
    Type: Grant
    Filed: July 27, 2001
    Date of Patent: May 1, 2007
    Assignee: Celestar Lexico-Sciences, Inc.
    Inventors: Yoshizumi Ishino, Isaac Cann, Arnaud Bocquier, Lidong Liu
  • Novel dna synthase
    Publication number: 20040014072
    Abstract: The object of the invention is to provide proteins that have both DNA primase activity and DNA polymerase activity. This subject is solved by a protein (p41) that has an amino acid sequence shown in SEQ ID NO: 1. This is for the first time that proteins that have both DNA primase activity and DNA polymerase activity were found. A protein (p46) that has amino acid sequence shown in SEQ ID NO: 2 forms a complex with p41, and enforces DNA synthesis activity that is independent and/or dependent from primer of p41.
    Type: Application
    Filed: July 14, 2003
    Publication date: January 22, 2004
    Inventors: Yoshizumi Ishino, Isaac Cann, Arnaud Bocquier, Lidong Liu