Patents by Inventor Isaac Cassar

Isaac Cassar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYSTEMS AND METHODS FOR EVALUATING NEUROMODULATION BASED ON EVOKED POTENTIALS
    Publication number: 20220111213
    Abstract: The present disclosure provides systems and methods relating to neuromodulation. In particular, the present disclosure provides systems and methods for evaluating the efficacy of neuromodulation therapy using evoked potential (EPs). The systems and methods disclosed herein facilitate the evaluation of both parameter-dependent and system-dependent changes in EPs as indicators of therapeutic efficacy.
    Type: Application
    Filed: October 13, 2021
    Publication date: April 14, 2022
    Applicant: Duke University
    Inventors: Isaac CASSAR, Warren GRILL
  • SYSTEMS AND METHODS FOR DETERMINING OPTIMAL TEMPORAL PATTERNS OF NEURAL STIMULATION
    Publication number: 20210322775
    Abstract: Systems and methods for determining optimal temporal patterns of neural stimulation are disclosed. According to an aspect, a method includes selecting a temporal pattern for neural stimulation. The method also includes determining a mutation type for altering a pattern of pulses of the temporal pattern. The method also includes identifying a location within the pattern of pulses of the temporal pattern to alter based on the determined mutation type. The method further includes altering the pattern of pulses of the temporal pattern based on the identified location and mutation type for application of the altered temporal pattern to a subject.
    Type: Application
    Filed: June 22, 2021
    Publication date: October 21, 2021
    Inventors: Warren M. Grill, Isaac Cassar, Nathan Titus
  • Systems and methods for determining optimal temporal patterns of neural stimulation
    Patent number: 11103708
    Abstract: Systems and methods for determining optimal temporal patterns of neural stimulation are disclosed. According to an aspect, a method includes selecting a temporal pattern for neural stimulation. The method also includes determining a mutation type for altering a pattern of pulses of the temporal pattern. The method also includes identifying a location within the pattern of pulses of the temporal pattern to alter based on the determined mutation type. The method further includes altering the pattern of pulses of the temporal pattern based on the identified location and mutation type for application of the altered temporal pattern to a subject.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: August 31, 2021
    Assignee: Duke University
    Inventors: Warren M. Grill, Isaac Cassar, Nathan Titus
  • SYSTEMS AND METHODS FOR DETERMINING OPTIMAL TEMPORAL PATTERNS OF NEURAL STIMULATION
    Publication number: 20200316384
    Abstract: Systems and methods for determining optimal temporal patterns of neural stimulation are disclosed. According to an aspect, a method includes selecting a temporal pattern for neural stimulation. The method also includes determining a mutation type for altering a pattern of pulses of the temporal pattern. The method also includes identifying a location within the pattern of pulses of the temporal pattern to alter based on the determined mutation type. The method further includes altering the pattern of pulses of the temporal pattern based on the identified location and mutation type for application of the altered temporal pattern to a subject.
    Type: Application
    Filed: June 1, 2017
    Publication date: October 8, 2020
    Inventors: Warren M. Grill, Isaac Cassar, Nathan Titus