Patents by Inventor Isaac Djerassi

Isaac Djerassi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4197847
    Abstract: In carrying out the process of this invention, there is a closed bag system comprising a first bag used for sedimenting the red cells and a second bag used for collecting the sedimented red cells. The two bags are connected by a flexible plastic transfer tube. The sedimenting bag has a second transfer tube leading thereto for introducing the packed red and white cells and the Saline solution of a sedimenting agent. A third tube is connected to the sedimenting bag for withdrawing white cells. The red cell bag has a second tube for the addition of plasma and a third tube for returning the plasma and red cells to a vein of the donor. As an optional feature, the withdrawn whole blood passes directly to an interrupted flow centrifuge which spins off the plasma and platelets, and from which the packed red and white cells are pumped to the sedimenting plastic bag.
    Type: Grant
    Filed: October 20, 1977
    Date of Patent: April 15, 1980
    Inventor: Isaac Djerassi
  • Patent number: 4111199
    Abstract: A leukopheresis process comprising removing a quantity of whole blood from the vein of a donor and depositing the blood in a plastic blood collection bag. The bag is then centrifuged in order to separate the red and white cells from the supernatant plasma and platelets. The platelet rich plasma is then expressed from the bag into a satellite bag. A solution comprising a red cell sedimenting agent in Normal Saline is then introduced into the bag containing the red and white cells. Preferably, the sedimenting agent is hydroxyethyl starch. After a short period of time, the red cells sediment to the bottom of the plastic bag, with the white cells, sedimenting agent and Saline remaining as the supernatant. The red cells are then removed from the bag, mixed with the platelet poor plasma, which is obtained by centrifuging the platelet rich plasma and removing the platelets, and the red cells and platelet poor plasma are returned to the donor by infusion into a vein.
    Type: Grant
    Filed: March 31, 1977
    Date of Patent: September 5, 1978
    Inventor: Isaac Djerassi