Patents by Inventor Isaac J. Pence

Isaac J. Pence has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYSTEM FOR FACILITATING DIFFERENTIATION BETWEEN PARATHYROID TISSUE AND THYROID TISSUE AND APPLICATIONS OF SAME
    Publication number: 20240041388
    Abstract: A system facilitating differentiation between parathyroid tissue and thyroid tissue of a subject comprises a light source for illuminating tissue in a target region in the neck area of the subject; a light delivery device that is optically coupled with the light source for delivering a beam of light from the light source to the tissue; a collection device for collecting optical signals emitted from the tissue responsive to the beam of light; and a detector for detecting the intensities of the optical signals emitted from the tissue, wherein differences in the detected intensities enable a user to differentiate between parathyroid tissue and thyroid tissue.
    Type: Application
    Filed: October 12, 2023
    Publication date: February 8, 2024
    Inventors: Anita Mahadevan-Jansen, Lisa White, John Phay, Constantine A. Paras, Elizabeth Kanter Bartz, Matthew D. Keller, Nicole Mathews, Jennifer Whisenant Amundson, Isaac J. Pence
  • Methods and systems for intra-operatively providing anatomical guidance in surgery
    Patent number: 10258275
    Abstract: In one aspect, the present invention relates to a process for intra-operatively providing anatomical guidance in endocrine surgery. In one embodiment, the process includes the steps of illuminating tissues in the neck area of a living subject with a beam of light having a predetermined wavelength, obtaining Raman data from light scattered from the illuminated tissues, finding Raman signatures corresponding to thyroid or parathyroid tissues from the obtained Raman data, and identifying the thyroid or parathyroid tissues from the corresponding Raman signatures.
    Type: Grant
    Filed: December 27, 2016
    Date of Patent: April 16, 2019
    Assignee: VANDERBILT UNIVERSITY
    Inventors: Anita Mahadevan-Jansen, Lisa White, John Phay, Constantine A. Paras, Elizabeth Kanter Bartz, Matthew D. Keller, Nicole Mathews, Jennifer Whisenant Amundson, Isaac J. Pence
  • Intra-operative use of fluorescence spectroscopy and applications of same
    Patent number: 9687190
    Abstract: In one aspect, the present invention relates to a process for intra-operatively providing anatomical guidance in endocrine surgery. In one embodiment, the process includes the steps of illuminating tissues in the neck area of a living subject with a beam of light having a predetermined wavelength, obtaining Raman data from light scattered from the illuminated tissues, finding Raman signatures corresponding to thyroid or parathyroid tissues from the obtained Raman data, and identifying the thyroid or parathyroid tissues from the corresponding Raman signatures.
    Type: Grant
    Filed: July 30, 2009
    Date of Patent: June 27, 2017
    Assignee: VANDERBILT UNIVERSITY
    Inventors: Anita Mahadevan-Jansen, Lisa White, John Phay, Constantine A. Paras, Elizabeth Kanter Bartz, Matthew D. Keller, Nicole Gasparino, Jennifer Gray Whisenant, Isaac J. Pence
  • INTRA-OPERATIVE USE OF FLUORESCENCE SPECTROSCOPY AND APPLICATIONS OF SAME
    Publication number: 20170105623
    Abstract: In one aspect, the present invention relates to a process for intra-operatively providing anatomical guidance in endocrine surgery. In one embodiment, the process includes the steps of illuminating tissues in the neck area of a living subject with a beam of light having a predetermined wavelength, obtaining Raman data from light scattered from the illuminated tissues, finding Raman signatures corresponding to thyroid or parathyroid tissues from the obtained Raman data, and identifying the thyroid or parathyroid tissues from the corresponding Raman signatures.
    Type: Application
    Filed: December 27, 2016
    Publication date: April 20, 2017
    Inventors: Anita Mahadevan-Jansen, Lisa White, John Phay, Constantine A. Paras, Elizabeth Kanter Bartz, Matthew D. Keller, Nicole Gasparino, Jennifer Gray Whisenant, Isaac J. Pence