Abstract: A system generates a visualization that represents progression of a cancer genome. To generate the visualization, the system obtains a genetic dataset derived from cancer cell samples of a patient and clinical data associated with the patient. A genomic data structure is generated to represent the genetic dataset, and clinical event data structures are generated to represent each of a plurality of clinical events based on the clinical data. The visualization includes interactive elements that are populated based on the genomic data structure and the clinical event data structures. When a user input associated with a first interactive element is detected, the system displays information associated with the first interactive element based on the genomic data structure or the clinical event data structures.

Abstract: A method of treating a waste stream comprising feeding a waste stream into a reactor constructed and arranged for a fast start and maintained in a thermophilic temperature regime of between about 50° C. and 62° C. for a HRT of less than or equal to 48 hours, wherein the reactor contents are maintained at a pH less than or equal to 6.5; drawing a portion of the contents of the reactor and feeding the drawn contents into a second reactor which is maintained in a mesophilic temperature regime of between about 28° C. to 38° C. for a HRT of at least thirteen days; and replacing the contents drawn from the first reactor with more waste from the waste stream. Alternately, the waste stream may be initially treated in a mesophilic reactor, followed by treatment in a thermophilic reactor, or a single stage thermophilic reactor may be used.