Abstract: A cultivator includes at least one cultivator row unit, each of the at least one cultivator row unit having a support assembly for securing the cultivator row unit to a tool bar, a shank, an earth working tool operatively connected to the shank, and at least one assembly for providing discrete incremental adjustment for at least one of (a) an angle of the earth working tool, (b) a depth of the earth working tool, and (c) a gauge wheel depth.

Abstract: An analytic method for improving the efficiency in identifying protein molecular effect information using low resolution x-ray crystallography, by selecting and imaging a protein sample with low resolution x-ray crystallography and assaying the data thus generated as to local ligand strain energy value, followed by calculating a real-space difference density Z for each element and compiling ZDD data therefrom, followed by determining the true protomer/tautomer state of the protein sample by calculating Scorei according to the following equation so that the highest Scorei signifies the molecular effect information: Scorei={((ZDDi??ZDD)/?ZDD)+((SEi??SE)/?SE)}.

Abstract: A cultivator includes at least one cultivator row unit, each of the at least one cultivator row unit having a support assembly for securing the cultivator row unit to a tool bar, a shank, an earth working tool operatively connected to the shank, and at least one assembly for providing discrete incremental adjustment for at least one of (a) an angle of the earth working tool, (b) a depth of the earth working tool, and (c) a gauge wheel depth.

Abstract: The invention is a diagnostic which overlays quantum mechanical analysis to x-ray crystallography or Cryo-EM data from one or more molecules, to assess and identify the real world conformation, protonation and solvent effects of one or more moieties in said molecule. This “overlay” occurs by scoring and identifying the protomer/tautomer or conformational states of the moieties using quantum mechanical analysis. The diagnostic results of the present invention accurately identify protein-ligand binding, rendered as an output to a user of a computer in which the x-ray crystallography or Cryo-EM data is analysed with semi-empirical Hamiltonian quantum mechanics.

Abstract: An analytic method for improving the efficiency in identifying protein molecular effect information using low resolution x-ray crystallography, by selecting and imaging a protein sample with low resolution x-ray crystallography and assaying the data thus generated as to local ligand strain energy value, followed by calculating a real-space difference density Z for each element and compiling ZDD data therefrom, followed by determining the true protomer/tautomer state of the protein sample by calculating Scorei according to the following equation so that the highest Scorei signifies the molecular effect information: Scorei={((ZDDi??ZDD)/?ZDD)+((SEi??SE)/?SE)}.

Abstract: An analytic method for improving the efficiency in identifying protein molecular effect information using low resolution x-ray crystallography, by selecting and imaging a protein sample with low resolution x-ray crystallography and assaying the data thus generated as to local ligand strain energy value, followed by calculating a real-space difference density Z for each element and compiling ZDD data therefrom, followed by determining the true protomer/tautomer state of the protein sample by calculating Scorei according to the following equation so that the highest Scorei signifies the molecuar effect information: Scorei={((ZDDi ??ZDD)/?ZDD)+((SEi ??SE)/?SE)}.

Abstract: The invention is a diagnostic which overlays quantum mechanical analysis to x-ray crystallography data from one or more proteins to assess and identify the real world conformation, protonation and solvent effects of one or more moieties in said protein. This “overlay” occurs by scoring and identifying the protomer/tautomer states of the moieties using quantum mechanical analysis.

Abstract: The invention relates to new antimicrobial compounds derived from nisin. In particular, the compounds are based on the unsubstituted nisin [1-12] structure, wherein said compounds have an antimicrobial activity exceeding the activity of the unsubstituted nisin [1-12] structure.

Abstract: Smoking article inspection systems configured to inspect smoking articles are provided. The systems may include imaging devices configured to capture images of an exterior of the smoking article and an analysis unit configured to analyze the images captured by the imaging devices. The analysis unit may execute an edge detection tool configured to determine a position of the smoking article based on an edge location of the smoking article and a defect detection tool configured to determine whether the smoking article is defective after the position of the smoking article is determined. The imaging devices may be configured to capture images of the smoking articles during the assembly thereof. Thereby, the analysis unit may determine any operations during assembly causing damage to the smoking article from analysis of the images of the smoking article captured during assembly. Related methods are also provided.

Abstract: The invention is a diagnostic which overlays quantum mechanical analysis to x-ray crystallography data from one or more proteins to assess and identify the real world conformation, protonation and solvent effects of one or more moieties in said protein. This “overlay” occurs by scoring and identifying the protomer/tautomer states of the moieties using quantum mechanical analysis.

Abstract: Smoking article inspection systems configured to inspect smoking articles are provided. The systems may include imaging devices configured to capture images of an exterior of the smoking article and an analysis unit configured to analyze the images captured by the imaging devices. The analysis unit may execute an edge detection tool configured to determine a position of the smoking article based on an edge location of the smoking article and a defect detection tool configured to determine whether the smoking article is defective after the position of the smoking article is determined. The imaging devices may be configured to capture images of the smoking articles during the assembly thereof. Thereby, the analysis unit may determine any operations during assembly causing damage to the smoking article from analysis of the images of the smoking article captured during assembly. Related methods are also provided.

Abstract: A speech replication system including a speech generation unit having a program running in a memory of the speech generation unit, the program executing the steps of receiving an audio stream, identifying words within the audio stream, analyzing each word to determine the audio characteristics of the speaker's voice, storing the audio characteristics of the speaker's voice in the memory, receiving text information, converting the text information into an output audio stream using the audio characteristics of the speaker stored in the memory, and playing the output audio stream.

Abstract: A method and apparatus are provided for a graded PECVD process that continuously modulates a set of flow and pressure conditions while the plasma power is turned on and a film is being deposited. A feedback mechanism specific to a give deposition recipe is used to generate, optimize and maintain a dynamic profile for a first input process parameter that produces a desired dynamic profile for a first output process parameter. An iterative approach produces a gradually converging series of dynamic profiles of an input profile parameter, which eventually succeeds in producing the desired dynamic profile for the first output process parameter of the graded PECVD process.

Abstract: Damaged low-density silicon oxide-based films having an Si—O backbone are repaired using a method for driving a self-limiting healing process. According to an example embodiment of the present invention, a deposition precursor and an oxidizer are introduced to a damaged side wall region of a low-density silicon oxide-based film. The unstable damaged portion of the film reacts with the deposition precursor and a thin repair film is grown within the interfacial layer of the damaged film. The repair film provides a strengthened interface, protects the underlying sensitive material from further chemical damage, and can improve the ability to integrate the film.

Abstract: Damaged low-density silicon oxide-based films having an Si-O backbone are repaired using a method for driving a self-limiting healing process. According to an example embodiment of the present invention, a deposition precursor and an oxidizer are introduced to a damaged side wall region of a low-density silicon oxide-based film. The unstable damaged portion of the film reacts with the deposition precursor and a thin repair film is grown within the interfacial layer of the damaged film. The repair film provides a strengthened interface, protects the underlying sensitive material from further chemical damage, and can improve the ability to integrate the film.