Patents by Inventor Isaac MONREAL

Isaac MONREAL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of membrane inhibitors to enhance vaccine development against enveloped viruses
    Patent number: 12728161
    Abstract: The present application relates to method of vaccinating a subject against infection by an enveloped virus. The method includes providing a compound of the Formula (I) as described herein, and contacting the compound of Formula (I) with an isolated enveloped virus, having a membrane, to inactivate the membrane of the isolated enveloped virus. The subject is then treated with the enveloped virus having an inactivated membrane to vaccinate the subject against the enveloped virus. Further disclosed is an ex vivo vaccine composition including the compound of Formula (I) and an enveloped virus.
    Type: Grant
    Filed: November 6, 2020
    Date of Patent: September 8, 2026
    Assignee: CORNELL UNIVERSITY
    Inventors: Hector Aguilar-Carreno, Isaac Monreal, David Buchholz
  • USE OF MEMBRANE INHIBITORS TO ENHANCE VACCINE DEVELOPMENT AGAINST ENVELOPED VIRUSES
    Publication number: 20220401554
    Abstract: The present application relates to method of vaccinating a subject against infection by an enveloped virus. The method includes providing a compound of the Formula (I) as described herein, and contacting the compound of Formula (I) with an isolated enveloped virus, having a membrane, to inactivate the membrane of the isolated enveloped virus. The subject is then treated with the enveloped virus having an inactivated membrane to vaccinate the subject against the enveloped virus. Further disclosed is an ex vivo vaccine composition including the compound of Formula (I) and an enveloped virus.
    Type: Application
    Filed: November 6, 2020
    Publication date: December 22, 2022
    Inventors: Hector AGUILAR-CARRENO, Isaac MONREAL, David BUCHHOLZ