Patents by Inventor Isaac Perry
Isaac Perry has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230380743Abstract: Systems, devices, and methods for interfacing with biological tissue are described herein. An example electrode patch as described herein includes a flexible substrate and an electrode array arranged on the flexible substrate. The electrode array includes a plurality of electrodes, where each of the plurality of electrodes is formed of a hydrogel. Additionally, each of the plurality of electrodes defines a raised geometry. Additionally, an example system includes the electrode patch, which is configured to interface with a subject's skin, and an electronics module operably coupled to the electrode array.Type: ApplicationFiled: March 21, 2023Publication date: November 30, 2023Inventors: Isaac Perry Clements, Anna Harrison, Edgar Brown, Amanda Preyer, James David Ross, Andrew Willsie, Maximilian Sonntag
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Patent number: 11654048Abstract: Assemblies for storing, handling, transporting, viewing, evaluating, and/or shipping corneal tissue are provided. The assembly includes a corneal tissue carrier, optimized for DSAEK and UT-DSAEK corneal grafts, within a transport vial, the transport vial removably coupled to a stabilization base, wherein the ease of access to the graft carrier allows administering the corneal tissue sample to a patient in rapid succession so that more surgeries can be performed by a single surgeon in a single day.Type: GrantFiled: February 22, 2022Date of Patent: May 23, 2023Assignee: MIRACLES IN SIGHTInventor: Isaac Perry
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Patent number: 11612344Abstract: Systems, devices, and methods for interfacing with biological tissue are described herein. An example electrode patch as described herein includes a flexible substrate and an electrode array arranged on the flexible substrate. The electrode array includes a plurality of electrodes, where each of the plurality of electrodes is formed of a hydrogel. Additionally, each of the plurality of electrodes defines a raised geometry. Additionally, an example system includes the electrode patch, which is configured to interface with a subject's skin, and an electronics module operably coupled to the electrode array.Type: GrantFiled: November 4, 2019Date of Patent: March 28, 2023Assignee: BioCircuit Technologies, Inc.Inventors: Isaac Perry Clements, Anna Harrison, Edgar Brown, Amanda Preyer, James David Ross, Andrew Willsie, Maximilian Sonntag
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Publication number: 20220349869Abstract: A scalable, real-time, label-free, electrode- or optical-based cell monitoring system for integration into a cell culture incubator is described herein. An example system includes (1) cell culture consumables with integrated electrodes and/or optics for growing and monitoring cells, (2) incubator trays for consumable organization and recording, and (3) a system console, external to the incubator, for connecting multiple incubator trays. Without perturbing the cell culture, the system is capable of monitoring multiple culture attributes for each cell culture consumable simultaneously. These attributes can include, but are not limited to, cell growth, proliferation, morphology, media pH, or media oxygen. The system can support multiple trays, which permits monitoring dozens to hundreds of consumables simultaneously, including a mixture of consumables of various sizes. In addition to monitoring adherent cells, the disclosed technology can be readily adapted for monitoring of cell suspensions.Type: ApplicationFiled: January 27, 2020Publication date: November 3, 2022Inventors: Michael Antony CLEMENTS, Isaac Perry CLEMENTS, Thomas J. O'BRIEN, James David ROSS, Daniel Christopher MILLARD, Andrew WILLSIE, Edgar A. BROWN, Robert Dixon GRIER, Jr., Amanda Jervis PREYER, Denise Danielle SULLIVAN
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Publication number: 20220175509Abstract: Assemblies for storing, handling, transporting, viewing, evaluating, and/or shipping corneal tissue are provided. The assembly includes a corneal tissue carrier, optimized for DSAEK and UT-DSAEK corneal grafts, within a transport vial, the transport vial removably coupled to a stabilization base, wherein the ease of access to the graft carrier allows administering the corneal tissue sample to a patient in rapid succession so that more surgeries can be performed by a single surgeon in a single day.Type: ApplicationFiled: February 22, 2022Publication date: June 9, 2022Inventor: Isaac Perry
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Publication number: 20220054824Abstract: An example device for repairing a tissue is described herein. The device can include a flexible carrier layer, and a support member including a plurality of micro-protrusions extending therefrom. The support member can be at least partially integrated with the flexible carrier layer. Additionally, the flexible carrier layer can be configured to cover at least a portion of the tissue, and the micro-protrusions can be configured to mechanically interface with the tissue.Type: ApplicationFiled: November 5, 2021Publication date: February 24, 2022Inventors: Jonathan Isaacs, Isaac Perry Clements, Andrew Willsie, James David Ross, Alex Weidenbach
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Patent number: 11167131Abstract: An example device for repairing a tissue is described herein. The device can include a flexible carrier layer, and a support member including a plurality of micro-protrusions extending therefrom. The support member can be at least partially integrated with the flexible carrier layer. Additionally, the flexible carrier layer can be configured to cover at least a portion of the tissue, and the micro-protrusions can be configured to mechanically interface with the tissue.Type: GrantFiled: May 3, 2021Date of Patent: November 9, 2021Assignees: BioCircuit Technologies, Inc., Virginia Commonwealth UniversityInventors: Jonathan Isaacs, Isaac Perry Clements, Andrew Willsie, James David Ross, Alex Weidenbach
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Publication number: 20210252282Abstract: An example device for repairing a tissue is described herein. The device can include a flexible carrier layer, and a support member including a plurality of micro-protrusions extending therefrom. The support member can be at least partially integrated with the flexible carrier layer. Additionally, the flexible carrier layer can be configured to cover at least a portion of the tissue, and the micro-protrusions can be configured to mechanically interface with the tissue.Type: ApplicationFiled: May 3, 2021Publication date: August 19, 2021Inventors: Jonathan Isaacs, Isaac Perry Clements, Andrew Willsie, James David Ross, Alex Weidenbach
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Patent number: 10994130Abstract: An example device for repairing a nerve is described herein. The device can include a flexible carrier layer made of a biologic material, and a metallic support member including a plurality of micro-protrusions extending therefrom. The metallic support member can be at least partially integrated with the flexible carrier layer. Additionally, the flexible carrier layer can be configured to cover at least a portion of the nerve, and the micro-protrusions can be configured to attach to a superficial tissue of the nerve.Type: GrantFiled: September 6, 2017Date of Patent: May 4, 2021Assignees: BioCircuit Technologies, Inc., Virginia Commonwealth UniversityInventors: Isaac Perry Clements, Andrew Willsie, James David Ross, Alex Weidenbach, Jonathan Isaacs
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Patent number: 10989703Abstract: An electro-optical stimulation and recording system is disclosed, including a substrate and a plurality of wells coupled to the substrate. The system also includes at least one electrode set disposed proximate a respective one of the plurality of wells, wherein the electrode set comprises at least one electrode configured to collect an electric signal associated with at least a portion of the respective well. The system also includes a light-emitting element set corresponding to a respective one of the wells and configured to deliver optical stimulation to at least a portion of the respective well.Type: GrantFiled: June 7, 2019Date of Patent: April 27, 2021Assignee: Axion BioSystems, Inc.Inventors: Isaac Perry Clements, Amanda Jervis Preyer, Swaminathan Rajaraman, Daniel Christopher Millard, James David Ross
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Publication number: 20200138313Abstract: Systems, devices, and methods for interfacing with biological tissue are described herein. An example electrode patch as described herein includes a flexible substrate and an electrode array arranged on the flexible substrate. The electrode array includes a plurality of electrodes, where each of the plurality of electrodes is formed of a hydrogel. Additionally, each of the plurality of electrodes defines a raised geometry. Additionally, an example system includes the electrode patch, which is configured to interface with a subject's skin, and an electronics module operably coupled to the electrode array.Type: ApplicationFiled: November 4, 2019Publication date: May 7, 2020Inventors: Isaac Perry Clements, Anna Harrison, Edgar Brown, Amanda Preyer, James David Ross, Andrew Willsie, Maximilian Sonntag
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Publication number: 20200003753Abstract: An electro-optical stimulation and recording system is disclosed, including a substrate and a plurality of wells coupled to the substrate. The system also includes at least one electrode set disposed proximate a respective one of the plurality of wells, wherein the electrode set comprises at least one electrode configured to collect an electric signal associated with at least a portion of the respective well. The system also includes a light-emitting element set corresponding to a respective one of the wells and configured to deliver optical stimulation to at least a portion of the respective well.Type: ApplicationFiled: June 7, 2019Publication date: January 2, 2020Inventors: Isaac Perry Clements, Amanda Jervis Preyer, Swaminathan Rajaraman, Daniel Christopher Millard, James David Ross
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Patent number: 10317391Abstract: An electro-optical stimulation and recording system is disclosed, including a substrate and a plurality of wells coupled to the substrate. The system also includes at least one electrode set disposed proximate a respective one of the plurality of wells, wherein the electrode set comprises at least one electrode configured to collect an electric signal associated with at least a portion of the respective well. The system also includes a light-emitting element set corresponding to a respective one of the wells and configured to deliver optical stimulation to at least a portion of the respective well.Type: GrantFiled: June 6, 2016Date of Patent: June 11, 2019Assignee: Axion BioSystems, Inc.Inventors: Isaac Perry Clements, Amanda Jervis Preyer, Swaminathan Rajaraman, Daniel Christopher Millard, James David Ross
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Publication number: 20180064931Abstract: An example device for repairing a nerve is described herein. The device can include a flexible carrier layer made of a biologic material, and a metallic support member including a plurality of micro-protrusions extending therefrom. The metallic support member can be at least partially integrated with the flexible carrier layer. Additionally, the flexible carrier layer can be configured to cover at least a portion of the nerve, and the micro-protrusions can be configured to attach to a superficial tissue of the nerve.Type: ApplicationFiled: September 6, 2017Publication date: March 8, 2018Inventors: Isaac Perry Clements, Andrew Willsie, James David Ross, Alex Weidenbach, Jonathan Isaacs
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Publication number: 20170038361Abstract: An electro-optical stimulation and recording system is disclosed, including a substrate and a plurality of wells coupled to the substrate. The system also includes at least one electrode set disposed proximate a respective one of the plurality of wells, wherein the electrode set comprises at least one electrode configured to collect an electric signal associated with at least a portion of the respective well. The system also includes a light-emitting element set corresponding to a respective one of the wells and configured to deliver optical stimulation to at least a portion of the respective well.Type: ApplicationFiled: June 6, 2016Publication date: February 9, 2017Inventors: Isaac Perry Clements, Amanda Jervis Preyer, Swaminathan Rajaraman, Daniel Christopher Millard, James David Ross
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Publication number: 20160161465Abstract: An electro-optical stimulation and recording system is disclosed, including a substrate and a plurality of wells coupled to the substrate. The system also includes at least one electrode set disposed proximate a respective one of the plurality of wells, wherein the electrode set comprises at least one electrode configured to collect an electric signal associated with at least a portion of the respective well. The system also includes a light-emitting element set corresponding to a respective one of the wells and configured to deliver optical stimulation to at least a portion of the respective well.Type: ApplicationFiled: February 11, 2016Publication date: June 9, 2016Inventors: Isaac Perry Clements, Amanda Jervis Preyer, Swaminathan Rajaraman, Daniel Christopher Millard, James David Ross
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Patent number: 9360469Abstract: An electro-optical stimulation and recording system is disclosed, including a substrate and a plurality of wells coupled to the substrate. The system also includes at least one electrode set disposed proximate a respective one of the plurality of wells, wherein the electrode set comprises at least one electrode configured to collect an electric signal associated with at least a portion of the respective well. The system also includes a light-emitting element set corresponding to a respective one of the wells and configured to deliver optical stimulation to at least a portion of the respective well.Type: GrantFiled: February 11, 2016Date of Patent: June 7, 2016Assignee: Axion BioSystems, Inc.Inventors: Isaac Perry Clements, Amanda Jervis Preyer, Swaminathan Rajaraman, Daniel Christopher Millard, James David Ross
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Patent number: 9279797Abstract: An electro-optical stimulation and recording system is disclosed, including a substrate and a plurality of wells coupled to the substrate. The system also includes at least one electrode set disposed proximate a respective one of the plurality of wells, wherein the electrode set comprises at least one electrode configured to collect an electric signal associated with at least a portion of the respective well. The system also includes a light-emitting element set corresponding to a respective one of the wells and configured to deliver optical stimulation to at least a portion of the respective well.Type: GrantFiled: June 12, 2015Date of Patent: March 8, 2016Assignee: AXION BIOSYSTEMS, INC.Inventors: Isaac Perry Clements, Amanda Jervis Preyer, Swaminathan Rajaraman, Daniel Christopher Millard, James David Ross
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Publication number: 20150362476Abstract: An electro-optical stimulation and recording system is disclosed, including a substrate and a plurality of wells coupled to the substrate. The system also includes at least one electrode set disposed proximate a respective one of the plurality of wells, wherein the electrode set comprises at least one electrode configured to collect an electric signal associated with at least a portion of the respective well. The system also includes a light-emitting element set corresponding to a respective one of the wells and configured to deliver optical stimulation to at least a portion of the respective well.Type: ApplicationFiled: June 12, 2015Publication date: December 17, 2015Inventors: Isaac Perry Clements, Amanda Jervis Preyer, Swaminathan Rajaraman, Daniel Christopher Millard, James David Ross