Abstract: Systems and methods for high-bandwidth, minimally invasive brain-computer interfaces (BCIs) are disclosed. The BCIs are configured for deployment and operation in conjunction with a comprehensive interventional electrophysiology procedural suite. Three primary methods of minimally invasive electrode array delivery are disclosed: (1) cortical surface delivery, (2) ventricular delivery, and (3) endovascular delivery. Additionally, systems and methods for interacting with such high-bandwidth electrode arrays are discussed, including real-time imaging, signal processing, and neural decoding. Systems and methods for architectures for accelerating the underlying computational processes (such as graphics processing units or tensor processing units) are also discussed. Multiple applications of BCIs are discussed, with emphasis on restoration, rehabilitation, and augmentation of neurologic function.

Abstract: A glucose fuel cell for reception into a given constrained volume of implantation in a vertebrate in which the glucose fuel cell has access to fluid containing glucose. The fuel cell includes an anode adapted to oxidize the glucose, a cathode adapted to reduce an oxidant, and a membrane disposed between the anode and the cathode and separating the anode from the cathode. At least one of the anode or cathode define a flexible sheet that is geometrically deformed to be receivable into the given constrained volume of implantation and increase volumetric power density. Related methods of making a glucose fuel cell of this type and implantable assemblies including the glucose fuel cell are also disclosed.

Abstract: A glucose fuel cell for reception into a given constrained volume of implantation in a vertebrate in which the glucose fuel cell has access to fluid containing glucose. The fuel cell includes an anode adapted to oxidize the glucose, a cathode adapted to reduce an oxidant, and a membrane disposed between the anode and the cathode and separating the anode from the cathode. At least one of the anode or cathode define a flexible sheet that is geometrically deformed to be receivable into the given constrained volume of implantation and increase volumetric power density. Related methods of making a glucose fuel cell of this type and implantable assemblies including the glucose fuel cell are also disclosed.

Abstract: A portable apparatus for the non-invasive, simultaneous, self-testing of fetal and maternal signals which comprises: a user display means to indicate that the device is operational; an ultrasonic means connected to the device for detecting fetal heart rate; a detection means connected to the device for detecting maternal input signals; signal processing means including a logarithmic amplification means for simultaneously processing fetal heart rate and maternal input signals; and a communication linking mean for the simultaneous transmission of fetal heart rate and maternal input data to a remote output device.

Abstract: A portable apparatus for the non-invasive, simultaneous, self-testing of fetal and maternal signals which comprises: a user display means to indicate that the device is operational, an ultrasonic means to detect fetal heart rate connected to said device, a detection means for maternal input signal connected to said device, wherein the device has signal processing means for simultaneously processing fetal heart rate and maternal input signals, and also has a communication linking means for the simultaneous transmission of fetal heart rate and maternal input data to a remote output device.