Patents by Inventor Isaac Yaniv

Isaac Yaniv has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11045489
    Abstract: Described herein are methods for determining the prognosis of a patient diagnosed with Acute Lymphoblastic Leukemia (ALL), and particularly determining the risk of disease relapse following standard treatment. Also described are systems of treatment that are directed by a health care provider, and which include the described prognostic methods and the treatments recommended for patients determined to have a specific relapse risk.
    Type: Grant
    Filed: September 11, 2019
    Date of Patent: June 29, 2021
    Assignee: MOR RESEARCH APPLICATIONS LTD.
    Inventors: Smadar Avigad, Isaac Yaniv, Keren Shichrur
  • Publication number: 20210180138
    Abstract: Described herein is the correlation between miR-451 expression and the increased benefit of a treatment modality of solid tumors that effects miR-451 modulated metabolic pathways. Such modalities include NAMPT inhibitors and/or PARP inhibitors. Also described herein are methods for treatment of solid tumors that include determining whether treatment of the tumor would benefit from inhibition of NAMPT and/or PARP and if so, treating the patient afflicted with the tumor with NAMPT and/or PARP inhibitors.
    Type: Application
    Filed: November 6, 2018
    Publication date: June 17, 2021
    Applicant: Mor Research Applications Ltd.
    Inventors: Keren SHICHRUR, Isaac YANIV, Smadar AVIGAD
  • Patent number: 10557173
    Abstract: The present invention relates to prognostic methods and kits for the assessment and monitoring of relapse-free or disease-free survival of ALL patients. The detection is based on the use of detecting nucleic acids, specific for determination of the expression of at least one of miR-151-5p and miR-451 in a test sample. The invention thereby also provides methods and kits for monitoring and early diagnosis of cancerous disorders associated with low miR-151-5p and/or miR-451 expression, specifically ALL, and appropriate associated treatments thereof.
    Type: Grant
    Filed: February 3, 2016
    Date of Patent: February 11, 2020
    Assignee: MOR RESEARCH APPLICATIONS LTD.
    Inventors: Smadar Avigad, Isaac Yaniv
  • Publication number: 20190388457
    Abstract: Described herein are methods for determining the prognosis of a patient diagnosed with Acute Lymphoblastic Leukemia (ALL), and particularly determining the risk of disease relapse following standard treatment. Also described are systems of treatment that are directed by a health care provider, and which include the described prognostic methods and the treatments recommended for patients determined to have a specific relapse risk.
    Type: Application
    Filed: September 11, 2019
    Publication date: December 26, 2019
    Applicant: MOR RESEARCH APPLICATIONS LTD.
    Inventors: Smadar AVIGAD, Isaac YANIV, Keren SHICHRUR
  • Publication number: 20190167711
    Abstract: Provided herein is the use of miR-451 as a biomarker in prognosis of anti-ALL treatment modalities, in early diagnosis of ALL relapse risk, and/or in identifying an ALL patient that can benefit from a treatment modality that affects one or more miR-451-related metabolic pathways.
    Type: Application
    Filed: February 11, 2019
    Publication date: June 6, 2019
    Inventors: Smadar AVIGAD, Isaac YANIV, Keren SHICHRUR
  • Publication number: 20180179596
    Abstract: Described herein are methods of cancer diagnosis through monitoring the presence and activity of the KANSL1 gene, and particularly the effects of KANSL1 overexpression on specific histone acetylation. Cancer treatment with histone acetyltransferase inhibitors and deacetylase agents is also described.
    Type: Application
    Filed: June 24, 2016
    Publication date: June 28, 2018
    Inventors: Smadar AVIGAD, Isaac YANIV, Lital SELA-TZURIANO
  • Publication number: 20170268070
    Abstract: Described herein are methods for determining the prognosis of a patient diagnosed with Acute Lymphoblastic Leukemia (ALL), and particularly determining the risk of disease relapse following standard treatment. Also described are systems of treatment that are directed by a health care provider, and which include the described prognostic methods and the treatments recommended for patients determined to have a specific relapse risk.
    Type: Application
    Filed: July 30, 2015
    Publication date: September 21, 2017
    Applicant: MOR RESEARCH APPLICATIONS LTD.
    Inventors: Smadar AVIGAD, Isaac YANIV, Keren SHICHRUR
  • Publication number: 20170252364
    Abstract: Provided herein are compositions for treatment of Acute Lymphoblastic Leukemia (ALL) and methods of their use, including inhibiting ALL relapse. Further provided herein are systems of treatment that are directed by a health care provider, and which combine prognostic methods for determining ALL relapse and the described treatments.
    Type: Application
    Filed: July 30, 2015
    Publication date: September 7, 2017
    Inventors: Smadar AVIGAD, Isaac YANIV, Keren SHICHRUR
  • Publication number: 20160222464
    Abstract: The present invention relates to prognostic methods and kits for the assessment and monitoring of relapse-free or disease-free survival of ALL patients. The detection is based on the use of detecting nucleic acids, specific for determination of the expression of at least one of miR-151-5p and miR-451 in a test sample. The invention thereby also provides methods and kits for monitoring and early diagnosis of cancerous disorders associated with low miR-151-5p and/or miR-451 expression, specifically ALL, and appropriate associated treatments thereof.
    Type: Application
    Filed: February 3, 2016
    Publication date: August 4, 2016
    Applicant: Mor Research Applications Ltd.
    Inventors: Smadar Avigad, Isaac Yaniv
  • Publication number: 20130196335
    Abstract: The present invention relates to prognostic methods and kits for the assessment and monitoring of relapse-free or disease-free survival of ALL patients. The detection is based on the use of detecting nucleic acids, specific for determination of the expression of at least one of miR-151-5p and miR-451 in a test sample. The invention thereby also provides methods and kits for monitoring and early diagnosis of cancerous disorders associated with low miR-151-5p and/or miR-451 expression, specifically ALL.
    Type: Application
    Filed: March 19, 2013
    Publication date: August 1, 2013
    Applicant: MOR RESEARCH APPLICATIONS LTD.
    Inventors: Smadar AVIGAD, Isaac Yaniv
  • Publication number: 20110192989
    Abstract: Embodiments of the invention are directed to a system for treatment of material by microwave radiation. The system may include a casing, a waveguide connected to the casing to conduct microwave radiation from a radiation source into the casing, an inner container transparent to microwave radiation, the container having an inlet to receive material to be treated and an outlet to discharge treated material and a transport unit to carry the treated material.
    Type: Application
    Filed: June 18, 2009
    Publication date: August 11, 2011
    Inventors: Isaac Yaniv, Ben Zion Livneh
  • Publication number: 20110146544
    Abstract: Provided is a novel method and system to separate magnetically non-susceptible impurities from coal intended for combustion, and it includes the removal of such impurities together with magnetically susceptible impurities that are collocated within the same lump of coal, prior to the combustion of the coal, by the use of the magnetic properties of the magnetically susceptible impurities. The described subject matter is based on the fact that the former impurities are normally collocated in the same lumps of coal as the latter, especially as far as pyrite and cinnabar are concerned, provided the lumps have not been liberated, in particular, they meet the requirement that at least 50% by mass of the coal lumps should be at least 2 mm in maximum dimension.
    Type: Application
    Filed: July 8, 2008
    Publication date: June 23, 2011
    Applicant: MICROCOAL INC.
    Inventors: Isaac Yaniv, Ben-Zion Livneh
  • Publication number: 20090227464
    Abstract: The present invention provides a method for assessing the prognosis of Ewing's Sarcoma patients comprising determining the expression pattern of a defined set of genes in tumor material obtained from said patients, and assigning said expression pattern to either a good prognosis or poor prognosis group.
    Type: Application
    Filed: June 30, 2004
    Publication date: September 10, 2009
    Inventors: Smadar Avigad, Isaac Yaniv, Rina Zaizov, Haim Marx, Anat Ohali
  • Publication number: 20070158174
    Abstract: Method for managing electric power generated during periods of low demand, in an electric power market where consumption of electric power exhibits periods of different demands. The method includes upgrading solid fossil fuel by electromagnetic radiation (EMR) upgrading during the periods of low demand, storing and utilization of the upgraded fuel. Fuel utilization may include burning for electric power generation during periods of high demand, burning in another heat-consuming industrial process, or trading the fuel with another business entity. The EMR upgrading used in the method includes reducing the inherent moisture content in the upgraded fossil fuel at least in half.
    Type: Application
    Filed: February 5, 2007
    Publication date: July 12, 2007
    Inventors: Ben Livneh, Eli Barnea, Isaac Yaniv
  • Patent number: 6685908
    Abstract: Disclosed is a novel form of particulate precipitated aragonite calcium carbonate and a novel process for producing it.
    Type: Grant
    Filed: March 6, 2000
    Date of Patent: February 3, 2004
    Assignee: 3P Technologies Ltd.
    Inventor: Isaac Yaniv
  • Publication number: 20030213937
    Abstract: Disclosed is a novel form of particulate precipitated aragonite, and a novel process for producing it.
    Type: Application
    Filed: December 9, 2002
    Publication date: November 20, 2003
    Inventor: Isaac Yaniv
  • Publication number: 20030161894
    Abstract: Disclosed is a novel form of particulate precipitated aragonite, and a novel process for producing it.
    Type: Application
    Filed: September 5, 2001
    Publication date: August 28, 2003
    Applicant: 3P TECHNOLOGIES LTD.
    Inventor: Isaac Yaniv
  • Publication number: 20010033820
    Abstract: Disclosed is a novel form of particulate precipitated aragonite, a novel process for producing it and compositions containing it.
    Type: Application
    Filed: February 8, 2001
    Publication date: October 25, 2001
    Inventor: Isaac Yaniv