Patents by Inventor Isaac Yue

Isaac Yue has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of increasing the efficacy of antibiotics by compexing with cyclodextrins
    Patent number: 6699505
    Abstract: The present invention provides methods of increasing the biological activity of a bioactive agent by complexing the bioactive agent with a complexing agent. In one preferred embodiment, the bioactive agent is an antibiotic and the complexing agent is a cyclodextrin. However, the invention may be extended to include any drugs as bioactive agents. In certain preferred embodiments, the bioactive agent fits into a hydrophobic core of a complexing agent.
    Type: Grant
    Filed: October 17, 2001
    Date of Patent: March 2, 2004
    Assignee: Massachusetts Institute of Technology
    Inventors: Venkatram R. Shastri, Isaac Yue, Patrice Hildgen, Ruben Dario Sinisterra, Robert Langer
  • Drug delivery composition and device
    Patent number: 6582717
    Abstract: Drug delivery composition. The composition includes a polymeric material, a complexing agent, and a bioactive agent complexed with the complexing agent. The polymeric material, the complexing agent and the bioactive agent are formed into a delivery matrix. The delivery matrix is particularly adapted for placement below the gum line in a periodontal cavity.
    Type: Grant
    Filed: April 7, 2000
    Date of Patent: June 24, 2003
    Assignee: Massachusetts Institute of Technology
    Inventors: Venkatram R. Shastri, Isaac Yue, Robert S. Langer
  • Method of increasing the efficacy of antibiotics by compexing with cyclodextrins
    Publication number: 20030078215
    Abstract: The present invention provides methods of increasing the biological activity of a bioactive agent by complexing the bioactive agent with a complexing agent. In one preferred embodiment, the bioactive agent is an antibiotic and the complexing agent is a cyclodextrin. However, the invention may be extended to include any drugs as bioactive agents. In certain preferred embodiments, the bioactive agent fits into a hydrophobic core of a complexing agent.
    Type: Application
    Filed: October 17, 2001
    Publication date: April 24, 2003
    Inventors: Venkatram R. Shastri, Isaac Yue, Patrice Hildgen, Ruben Dario Sinisterra, Robert Langer