Patents by Inventor Isabel F. Fernandez

Isabel F. Fernandez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stereospecific synthesis of isocephalosporins and 2-oxa isocephalosporins
    Patent number: 4440682
    Abstract: A process is described whereby a synthetically produced 4-styryl-cis-3,4-azetidinone is converted to an isocephalosporin or its 2-oxa analog. The process is based upon the condensation of enamine and imine synthons. Novel intermediate azetidinones are also disclosed. Control of the stereochemical course of the process allows economical, high yield preparation of the racemic form of the product or when a single enantiomer of the imine synthon derived from the .beta.-hydroxy-.alpha.-amino acid starting material is used, both enantiomers of the product may be prepared and separated without optical resolution.
    Type: Grant
    Filed: April 6, 1981
    Date of Patent: April 3, 1984
    Assignee: Laboratorio Farmaceutico Quimico "LaFarquim, S.A."
    Inventors: Ajay K. Bose, Isabel F. Fernandez, Kanti J. Gala